| Full name: leukocyte immunoglobulin like receptor A6 | Alias Symbol: ILT8|CD85b | ||
| Type: protein-coding gene | Cytoband: 19q13.42 | ||
| Entrez ID: 79168 | HGNC ID: HGNC:15495 | Ensembl Gene: ENSG00000244482 | OMIM ID: |
| Drug and gene relationship at DGIdb | |||
LILRA6 involved pathways:
| KEGG pathway | Description | View |
|---|---|---|
| hsa04380 | Osteoclast differentiation |
Expression of LILRA6:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | LILRA6 | 79168 | 208594_x_at | 0.1243 | 0.8338 | |
| GSE20347 | LILRA6 | 79168 | 208594_x_at | -0.0730 | 0.3642 | |
| GSE23400 | LILRA6 | 79168 | 208594_x_at | 0.0101 | 0.8034 | |
| GSE26886 | LILRA6 | 79168 | 208594_x_at | -0.2096 | 0.1611 | |
| GSE29001 | LILRA6 | 79168 | 208594_x_at | -0.0893 | 0.5967 | |
| GSE38129 | LILRA6 | 79168 | 208594_x_at | -0.0767 | 0.2497 | |
| GSE45670 | LILRA6 | 79168 | 208594_x_at | 0.0614 | 0.5446 | |
| GSE53622 | LILRA6 | 79168 | 80950 | 0.5671 | 0.0286 | |
| GSE53624 | LILRA6 | 79168 | 80950 | 1.0097 | 0.0000 | |
| GSE63941 | LILRA6 | 79168 | 208594_x_at | 0.2517 | 0.0863 | |
| GSE77861 | LILRA6 | 79168 | 208594_x_at | 0.0498 | 0.6257 | |
| GSE97050 | LILRA6 | A_21_P0011714 | -0.1185 | 0.7898 | ||
| SRP007169 | LILRA6 | 79168 | RNAseq | 2.8632 | 0.0062 | |
| SRP064894 | LILRA6 | 79168 | RNAseq | 0.5716 | 0.1536 | |
| SRP133303 | LILRA6 | 79168 | RNAseq | 1.0040 | 0.0001 | |
| SRP159526 | LILRA6 | 79168 | RNAseq | 2.1490 | 0.0008 | |
| SRP193095 | LILRA6 | 79168 | RNAseq | 1.2524 | 0.0000 | |
| SRP219564 | LILRA6 | 79168 | RNAseq | 0.7551 | 0.2382 | |
| TCGA | LILRA6 | 79168 | RNAseq | 0.2544 | 0.2778 |
Upregulated datasets: 5; Downregulated datasets: 0.
Survival by LILRA6 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of LILRA6:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | LILRA6 | 79168 | 3 | 4 | 23 | |
| GSE20123 | LILRA6 | 79168 | 3 | 3 | 24 | |
| GSE43470 | LILRA6 | 79168 | 2 | 11 | 30 | |
| GSE46452 | LILRA6 | 79168 | 45 | 1 | 13 | |
| GSE47630 | LILRA6 | 79168 | 8 | 6 | 26 | |
| GSE54993 | LILRA6 | 79168 | 17 | 4 | 49 | |
| GSE54994 | LILRA6 | 79168 | 4 | 13 | 36 | |
| GSE60625 | LILRA6 | 79168 | 9 | 0 | 2 | |
| GSE74703 | LILRA6 | 79168 | 2 | 7 | 27 | |
| GSE74704 | LILRA6 | 79168 | 3 | 1 | 16 | |
| TCGA | LILRA6 | 79168 | 19 | 15 | 62 |
Total number of gains: 115; Total number of losses: 65; Total Number of normals: 308.
Somatic mutations of LILRA6:
Generating mutation plots.
Highly correlated genes for LILRA6:
Showing top 20/577 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| LILRA6 | SRGN | 0.761152 | 4 | 0 | 4 |
| LILRA6 | C1orf162 | 0.726617 | 4 | 0 | 4 |
| LILRA6 | C1QB | 0.718896 | 4 | 0 | 4 |
| LILRA6 | C1QA | 0.718579 | 4 | 0 | 4 |
| LILRA6 | GIMAP6 | 0.698888 | 3 | 0 | 3 |
| LILRA6 | C5AR1 | 0.697913 | 6 | 0 | 5 |
| LILRA6 | HSPB6 | 0.694883 | 3 | 0 | 3 |
| LILRA6 | LRRC25 | 0.690765 | 5 | 0 | 4 |
| LILRA6 | SLC2A5 | 0.684652 | 5 | 0 | 5 |
| LILRA6 | PRELP | 0.679533 | 3 | 0 | 3 |
| LILRA6 | IFI44L | 0.67874 | 3 | 0 | 3 |
| LILRA6 | C19orf38 | 0.67656 | 4 | 0 | 3 |
| LILRA6 | MTAP | 0.675127 | 4 | 0 | 3 |
| LILRA6 | CD93 | 0.674648 | 4 | 0 | 3 |
| LILRA6 | PLXNC1 | 0.67146 | 4 | 0 | 3 |
| LILRA6 | CYBB | 0.670274 | 6 | 0 | 6 |
| LILRA6 | MCEMP1 | 0.669393 | 3 | 0 | 3 |
| LILRA6 | MIER2 | 0.668029 | 3 | 0 | 3 |
| LILRA6 | SUCNR1 | 0.666635 | 5 | 0 | 5 |
| LILRA6 | SPI1 | 0.6649 | 5 | 0 | 5 |
For details and further investigation, click here
