IFI44L

 

Full name: interferon induced protein 44 like Alias Symbol: GS3686
Type: protein-coding gene Cytoband: 1p31.1
Entrez ID: 10964 HGNC ID: HGNC:17817 Ensembl Gene: ENSG00000137959 OMIM ID: 613975
Drug and gene relationship at DGIdb

 

Expression of IFI44L:

 

Dataset Gene EntrezID Probe Log2FC Adj.pValue Expression
GSE17351 IFI44L 10964 204439_at 0.4186 0.8691
GSE20347 IFI44L 10964 204439_at 2.3340 0.0002
GSE23400 IFI44L 10964 204439_at 1.2578 0.0000
GSE26886 IFI44L 10964 204439_at 2.4371 0.0112
GSE29001 IFI44L 10964 204439_at 2.6937 0.0005
GSE38129 IFI44L 10964 204439_at 1.4998 0.0016
GSE45670 IFI44L 10964 204439_at 2.1321 0.0088
GSE53622 IFI44L 10964 1664 1.3743 0.0000
GSE53624 IFI44L 10964 1664 1.9888 0.0000
GSE63941 IFI44L 10964 204439_at -0.0287 0.9895
GSE77861 IFI44L 10964 204439_at 0.4580 0.4287
GSE97050 IFI44L 10964 A_23_P45871 0.3428 0.5336
SRP007169 IFI44L 10964 RNAseq 3.8264 0.0000
SRP008496 IFI44L 10964 RNAseq 3.6503 0.0000
SRP064894 IFI44L 10964 RNAseq 2.7078 0.0000
SRP133303 IFI44L 10964 RNAseq 1.2184 0.0030
SRP159526 IFI44L 10964 RNAseq -0.1675 0.8411
SRP193095 IFI44L 10964 RNAseq 2.2820 0.0000
SRP219564 IFI44L 10964 RNAseq 1.8781 0.0541
TCGA IFI44L 10964 RNAseq 0.5001 0.0128

Upregulated datasets: 13; Downregulated datasets: 0.  

 

Survival by IFI44L expression:

 

GSE53622GSE53624TCGA

 

Note: Click image to view full size file.  

Copy number change of IFI44L:

 

Dataset Gene EntrezID Gain Loss Normal Detail
GSE15526 IFI44L 10964 0 7 23
GSE20123 IFI44L 10964 0 7 23
GSE43470 IFI44L 10964 4 2 37
GSE46452 IFI44L 10964 0 1 58
GSE47630 IFI44L 10964 8 6 26
GSE54993 IFI44L 10964 0 0 70
GSE54994 IFI44L 10964 6 3 44
GSE60625 IFI44L 10964 0 0 11
GSE74703 IFI44L 10964 3 2 31
GSE74704 IFI44L 10964 0 4 16
TCGA IFI44L 10964 9 24 63

Total number of gains: 30; Total number of losses: 56; Total Number of normals: 402.  

 

Somatic mutations of IFI44L:

 

Generating mutation plots.

 

Highly correlated genes for IFI44L:

 

Showing top 20/571 corelated genes with mean PCC>0.5.
Gene1 Gene2 Mean PCC Num. Datasets Num. PCC<0 Num. PCC>0.5
IFI44LIFI440.87208113013
IFI44LIFIT10.85324513013
IFI44LRSAD20.83732613013
IFI44LIFIT30.81259313013
IFI44LIFI60.80703213013
IFI44LDDX600.78932613012
IFI44LIFI350.77664513013
IFI44LIFITM10.7759641009
IFI44LCMPK20.768257907
IFI44LEPSTI10.765964807
IFI44LUSP410.757283303
IFI44LXAF10.75277513012
IFI44LHERC50.74550113011
IFI44LFCGR3A0.742095303
IFI44LUSP180.74141312012
IFI44LISG150.73656613011
IFI44LOAS20.73503613012
IFI44LMX10.7303812010
IFI44LIFIH10.71659311010
IFI44LIRF90.7088011009

For details and further investigation, click here