| Full name: SLIT and NTRK like family member 6 | Alias Symbol: FLJ22774 | ||
| Type: protein-coding gene | Cytoband: 13q31.1 | ||
| Entrez ID: 84189 | HGNC ID: HGNC:23503 | Ensembl Gene: ENSG00000184564 | OMIM ID: 609681 |
| Drug and gene relationship at DGIdb | |||
Expression of SLITRK6:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | SLITRK6 | 84189 | 232481_s_at | -0.7772 | 0.6027 | |
| GSE26886 | SLITRK6 | 84189 | 232481_s_at | 0.3887 | 0.6372 | |
| GSE45670 | SLITRK6 | 84189 | 232481_s_at | 0.5524 | 0.2506 | |
| GSE53622 | SLITRK6 | 84189 | 26371 | -0.8075 | 0.0047 | |
| GSE53624 | SLITRK6 | 84189 | 42328 | -0.4631 | 0.0214 | |
| GSE63941 | SLITRK6 | 84189 | 232481_s_at | -0.3798 | 0.8446 | |
| GSE77861 | SLITRK6 | 84189 | 232481_s_at | 0.3434 | 0.7472 | |
| GSE97050 | SLITRK6 | 84189 | A_33_P3230189 | 0.8458 | 0.1678 | |
| SRP007169 | SLITRK6 | 84189 | RNAseq | -0.9303 | 0.3709 | |
| SRP064894 | SLITRK6 | 84189 | RNAseq | 1.3866 | 0.0010 | |
| SRP133303 | SLITRK6 | 84189 | RNAseq | 0.2105 | 0.6996 | |
| SRP159526 | SLITRK6 | 84189 | RNAseq | 0.3057 | 0.7233 | |
| SRP193095 | SLITRK6 | 84189 | RNAseq | 0.0835 | 0.8354 | |
| TCGA | SLITRK6 | 84189 | RNAseq | 0.7782 | 0.0082 |
Upregulated datasets: 1; Downregulated datasets: 0.
Survival by SLITRK6 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of SLITRK6:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | SLITRK6 | 84189 | 3 | 11 | 16 | |
| GSE20123 | SLITRK6 | 84189 | 3 | 10 | 17 | |
| GSE43470 | SLITRK6 | 84189 | 2 | 12 | 29 | |
| GSE46452 | SLITRK6 | 84189 | 0 | 32 | 27 | |
| GSE47630 | SLITRK6 | 84189 | 3 | 27 | 10 | |
| GSE54993 | SLITRK6 | 84189 | 11 | 3 | 56 | |
| GSE54994 | SLITRK6 | 84189 | 3 | 15 | 35 | |
| GSE60625 | SLITRK6 | 84189 | 0 | 3 | 8 | |
| GSE74703 | SLITRK6 | 84189 | 1 | 10 | 25 | |
| GSE74704 | SLITRK6 | 84189 | 1 | 9 | 10 | |
| TCGA | SLITRK6 | 84189 | 13 | 34 | 49 |
Total number of gains: 40; Total number of losses: 166; Total Number of normals: 282.
Somatic mutations of SLITRK6:
Generating mutation plots.
Highly correlated genes for SLITRK6:
Showing top 20/75 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| SLITRK6 | PEG10 | 0.816962 | 3 | 0 | 3 |
| SLITRK6 | FAM107B | 0.783164 | 3 | 0 | 3 |
| SLITRK6 | PIP4K2A | 0.764872 | 3 | 0 | 3 |
| SLITRK6 | ELOVL5 | 0.74576 | 3 | 0 | 3 |
| SLITRK6 | PTPRB | 0.736747 | 3 | 0 | 3 |
| SLITRK6 | LIPT1 | 0.731098 | 3 | 0 | 3 |
| SLITRK6 | TCF7L2 | 0.73008 | 3 | 0 | 3 |
| SLITRK6 | ICK | 0.72969 | 3 | 0 | 3 |
| SLITRK6 | LIFR | 0.723485 | 3 | 0 | 3 |
| SLITRK6 | DCTN6 | 0.716256 | 3 | 0 | 3 |
| SLITRK6 | CXCR4 | 0.714913 | 3 | 0 | 3 |
| SLITRK6 | SOCS2 | 0.710356 | 3 | 0 | 3 |
| SLITRK6 | GBGT1 | 0.7098 | 3 | 0 | 3 |
| SLITRK6 | PRPS2 | 0.707636 | 3 | 0 | 3 |
| SLITRK6 | SGCE | 0.702987 | 3 | 0 | 3 |
| SLITRK6 | CSGALNACT1 | 0.695474 | 4 | 0 | 4 |
| SLITRK6 | SPON1 | 0.692383 | 3 | 0 | 3 |
| SLITRK6 | PTPRM | 0.69199 | 3 | 0 | 3 |
| SLITRK6 | MAN1A1 | 0.69025 | 3 | 0 | 3 |
| SLITRK6 | FAR2 | 0.688541 | 4 | 0 | 4 |
For details and further investigation, click here
