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Multi-Omics Database of ESCC

 

VAMP3

 

Full name: vesicle associated membrane protein 3 Alias Symbol: CEB
Type: protein-coding gene Cytoband: 1p36.23
Entrez ID: 9341 HGNC ID: HGNC:12644 Ensembl Gene: ENSG00000049245 OMIM ID: 603657
Drug and gene relationship at DGIdb

 

Expression of VAMP3:

 

Dataset Gene EntrezID Probe Log2FC Adj.pValue Expression
GSE17351 VAMP3 9341 201336_at -0.1687 0.7211
GSE20347 VAMP3 9341 201336_at -0.6789 0.0000
GSE23400 VAMP3 9341 201336_at -0.1748 0.0059
GSE26886 VAMP3 9341 201336_at -0.2901 0.1602
GSE29001 VAMP3 9341 201336_at -0.5221 0.1347
GSE38129 VAMP3 9341 201336_at -0.5424 0.0000
GSE45670 VAMP3 9341 201336_at -0.2976 0.1036
GSE53622 VAMP3 9341 20097 -0.3053 0.0000
GSE53624 VAMP3 9341 20097 -0.4167 0.0000
GSE63941 VAMP3 9341 201336_at -0.9155 0.0874
GSE77861 VAMP3 9341 201336_at -0.4803 0.1030
GSE97050 VAMP3 9341 A_23_P97532 0.1513 0.5101
SRP007169 VAMP3 9341 RNAseq -1.6110 0.0000
SRP008496 VAMP3 9341 RNAseq -1.2666 0.0000
SRP064894 VAMP3 9341 RNAseq -0.1830 0.1021
SRP133303 VAMP3 9341 RNAseq -0.0522 0.7732
SRP159526 VAMP3 9341 RNAseq -0.6549 0.0003
SRP193095 VAMP3 9341 RNAseq -0.6238 0.0000
SRP219564 VAMP3 9341 RNAseq -0.6376 0.0538
TCGA VAMP3 9341 RNAseq -0.0135 0.7635

Upregulated datasets: 0; Downregulated datasets: 2.  


 

Survival by VAMP3 expression:

 

GSE53622GSE53624TCGA

 

Note: Click image to view full size file.  


Copy number change of VAMP3:

 

Dataset Gene EntrezID Gain Loss Normal Detail
GSE15526 VAMP3 9341 2 5 23
GSE20123 VAMP3 9341 2 4 24
GSE43470 VAMP3 9341 6 5 32
GSE46452 VAMP3 9341 7 1 51
GSE47630 VAMP3 9341 8 4 28
GSE54993 VAMP3 9341 3 2 65
GSE54994 VAMP3 9341 14 3 36
GSE60625 VAMP3 9341 0 0 11
GSE74703 VAMP3 9341 5 3 28
GSE74704 VAMP3 9341 2 0 18
TCGA VAMP3 9341 11 22 63

Total number of gains: 60; Total number of losses: 49; Total Number of normals: 379.  


 

Somatic mutations of VAMP3:

 

Generating mutation plots.

 

Highly correlated genes for VAMP3:

 

Showing top 20/901 corelated genes with mean PCC>0.5.
Gene1 Gene2 Mean PCC Num. Datasets Num. PCC<0 Num. PCC>0.5
VAMP3RHBDD10.821962303
VAMP3LIPT10.811161303
VAMP3NUDT160.794813303
VAMP3ZNF2270.782783303
VAMP3PSMA50.768073303
VAMP3TPRG1L0.767387808
VAMP3HACL10.756887303
VAMP3TRAPPC80.756773404
VAMP3ZCCHC170.739448303
VAMP3HIC20.731603303
VAMP3SCFD10.726714303
VAMP3LYRM10.725106404
VAMP3ZNF120.721078303
VAMP3SLC25A270.72045303
VAMP3IRAK20.719739303
VAMP3C9orf780.715543303
VAMP3GLIS30.71435303
VAMP3PPP2R3C0.708686403
VAMP3ATP11B0.706022504
VAMP3THBS40.704955303

For details and further investigation, click here