| Full name: loss of heterozygosity, 12, chromosomal region 2 | Alias Symbol: LOH2CR12 | ||
| Type: non-coding RNA | Cytoband: 12p13.2 | ||
| Entrez ID: 503693 | HGNC ID: HGNC:26524 | Ensembl Gene: ENSG00000205791 | OMIM ID: |
| Drug and gene relationship at DGIdb | |||
Expression of LOH12CR2:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | LOH12CR2 | 503693 | 236311_at | -0.6742 | 0.3139 | |
| GSE26886 | LOH12CR2 | 503693 | 236311_at | 0.3031 | 0.0537 | |
| GSE45670 | LOH12CR2 | 503693 | 236311_at | -0.3317 | 0.0620 | |
| GSE53622 | LOH12CR2 | 503693 | 17104 | -0.2014 | 0.2144 | |
| GSE53624 | LOH12CR2 | 503693 | 17104 | -0.1215 | 0.4195 | |
| GSE63941 | LOH12CR2 | 503693 | 236311_at | -1.0986 | 0.0028 | |
| GSE77861 | LOH12CR2 | 503693 | 236311_at | -0.0544 | 0.4938 | |
| SRP064894 | LOH12CR2 | 503693 | RNAseq | -0.2086 | 0.4940 | |
| SRP133303 | LOH12CR2 | 503693 | RNAseq | -0.1788 | 0.5929 | |
| SRP159526 | LOH12CR2 | 503693 | RNAseq | 0.7074 | 0.2459 | |
| TCGA | LOH12CR2 | 503693 | RNAseq | -0.5486 | 0.0096 |
Upregulated datasets: 0; Downregulated datasets: 1.
Survival by LOH12CR2 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of LOH12CR2:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | LOH12CR2 | 503693 | 6 | 2 | 22 | |
| GSE20123 | LOH12CR2 | 503693 | 6 | 2 | 22 | |
| GSE43470 | LOH12CR2 | 503693 | 10 | 4 | 29 | |
| GSE46452 | LOH12CR2 | 503693 | 10 | 1 | 48 | |
| GSE47630 | LOH12CR2 | 503693 | 13 | 2 | 25 | |
| GSE54993 | LOH12CR2 | 503693 | 2 | 9 | 59 | |
| GSE54994 | LOH12CR2 | 503693 | 10 | 2 | 41 | |
| GSE60625 | LOH12CR2 | 503693 | 0 | 1 | 10 | |
| GSE74703 | LOH12CR2 | 503693 | 9 | 3 | 24 | |
| GSE74704 | LOH12CR2 | 503693 | 4 | 1 | 15 | |
| TCGA | LOH12CR2 | 503693 | 39 | 7 | 50 |
Total number of gains: 109; Total number of losses: 34; Total Number of normals: 345.
Somatic mutations of LOH12CR2:
Generating mutation plots.
Highly correlated genes for LOH12CR2:
Showing top 20/233 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| LOH12CR2 | APBB1 | 0.699379 | 4 | 0 | 3 |
| LOH12CR2 | MICU3 | 0.68798 | 4 | 0 | 3 |
| LOH12CR2 | FIBIN | 0.686029 | 3 | 0 | 3 |
| LOH12CR2 | NFASC | 0.675645 | 3 | 0 | 3 |
| LOH12CR2 | BMP4 | 0.665089 | 3 | 0 | 3 |
| LOH12CR2 | PIFO | 0.66289 | 4 | 0 | 3 |
| LOH12CR2 | C3orf18 | 0.653386 | 6 | 0 | 6 |
| LOH12CR2 | SLC25A5-AS1 | 0.653308 | 3 | 0 | 3 |
| LOH12CR2 | RASL12 | 0.649158 | 4 | 0 | 3 |
| LOH12CR2 | SLC45A1 | 0.647209 | 4 | 0 | 3 |
| LOH12CR2 | EBF1 | 0.640232 | 4 | 0 | 4 |
| LOH12CR2 | FAM117A | 0.638216 | 5 | 0 | 4 |
| LOH12CR2 | BEND5 | 0.637661 | 5 | 0 | 5 |
| LOH12CR2 | TRAM2-AS1 | 0.636666 | 5 | 0 | 5 |
| LOH12CR2 | SALL2 | 0.636563 | 4 | 0 | 4 |
| LOH12CR2 | ATP1A1-AS1 | 0.635372 | 4 | 0 | 3 |
| LOH12CR2 | LRRC49 | 0.633949 | 4 | 0 | 3 |
| LOH12CR2 | LRCH2 | 0.632898 | 5 | 0 | 5 |
| LOH12CR2 | PCDH9 | 0.632857 | 3 | 0 | 3 |
| LOH12CR2 | CLIP3 | 0.6324 | 6 | 0 | 6 |
For details and further investigation, click here
