LOXL1-AS1

 

Full name: LOXL1 antisense RNA 1 Alias Symbol: 
Type: non-coding RNA Cytoband: 15q24.1
Entrez ID: 100287616 HGNC ID: HGNC:44169 Ensembl Gene: ENSG00000261801 OMIM ID: 616800
Drug and gene relationship at DGIdb

 

Expression of LOXL1-AS1:

 

Dataset Gene EntrezID Probe Log2FC Adj.pValue Expression
GSE17351 LOXL1-AS1 100287616 232752_at 0.4494 0.5599
GSE26886 LOXL1-AS1 100287616 232752_at 1.8377 0.0002
GSE45670 LOXL1-AS1 100287616 232752_at 0.6968 0.1452
GSE53622 LOXL1-AS1 100287616 89641 0.5292 0.0000
GSE53624 LOXL1-AS1 100287616 89641 0.7600 0.0000
GSE63941 LOXL1-AS1 100287616 232752_at -0.6816 0.5663
GSE77861 LOXL1-AS1 100287616 232752_at 0.7609 0.0263
SRP007169 LOXL1-AS1 100287616 RNAseq 1.8099 0.0233
SRP064894 LOXL1-AS1 100287616 RNAseq 0.2049 0.4103
SRP133303 LOXL1-AS1 100287616 RNAseq 0.6799 0.0078
SRP159526 LOXL1-AS1 100287616 RNAseq 0.9802 0.0000
SRP193095 LOXL1-AS1 100287616 RNAseq 0.7099 0.0001
SRP219564 LOXL1-AS1 100287616 RNAseq 1.0633 0.0147

Upregulated datasets: 3; Downregulated datasets: 0.  


 

Survival by LOXL1-AS1 expression:

 

GSE53622GSE53624

 

Note: Click image to view full size file.  


Copy number change of LOXL1-AS1:

 

Dataset Gene EntrezID Gain Loss Normal Detail
GSE15526 LOXL1-AS1 100287616 8 0 22
GSE20123 LOXL1-AS1 100287616 8 0 22
GSE43470 LOXL1-AS1 100287616 4 6 33
GSE46452 LOXL1-AS1 100287616 3 7 49
GSE47630 LOXL1-AS1 100287616 8 10 22
GSE54993 LOXL1-AS1 100287616 5 6 59
GSE54994 LOXL1-AS1 100287616 5 7 41
GSE60625 LOXL1-AS1 100287616 4 0 7
GSE74703 LOXL1-AS1 100287616 4 3 29
GSE74704 LOXL1-AS1 100287616 4 0 16

Total number of gains: 53; Total number of losses: 39; Total Number of normals: 300.  


 

Somatic mutations of LOXL1-AS1:

 

Generating mutation plots.

 

Highly correlated genes for LOXL1-AS1:

 

Showing top 20/424 corelated genes with mean PCC>0.5.
Gene1 Gene2 Mean PCC Num. Datasets Num. PCC<0 Num. PCC>0.5
LOXL1-AS1SP40.769552303
LOXL1-AS1SEL1L30.766579303
LOXL1-AS1SYT10.755658303
LOXL1-AS1ZXDB0.749641303
LOXL1-AS1UBB0.702578303
LOXL1-AS1ACOT90.689477505
LOXL1-AS1FBRSL10.689204303
LOXL1-AS1SLC6A60.68885303
LOXL1-AS1FYN0.679752303
LOXL1-AS1ZNF2750.678783606
LOXL1-AS1ASAP20.678082303
LOXL1-AS1MXRA70.676295303
LOXL1-AS1SGTB0.672485303
LOXL1-AS1THAP100.672283403
LOXL1-AS1TNKS0.66694303
LOXL1-AS1PDE6D0.659735303
LOXL1-AS1FSTL30.658573303
LOXL1-AS1RILPL20.656543403
LOXL1-AS1SCCPDH0.6529605
LOXL1-AS1KIAA08950.652476303

For details and further investigation, click here