| Full name: THAP domain containing 10 | Alias Symbol: | ||
| Type: protein-coding gene | Cytoband: 15q23 | ||
| Entrez ID: 56906 | HGNC ID: HGNC:23193 | Ensembl Gene: ENSG00000129028 | OMIM ID: 612538 |
| Drug and gene relationship at DGIdb | |||
Expression of THAP10:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | THAP10 | 56906 | 219596_at | 0.1572 | 0.7831 | |
| GSE20347 | THAP10 | 56906 | 219596_at | 1.0822 | 0.0001 | |
| GSE23400 | THAP10 | 56906 | 219596_at | 0.1428 | 0.0030 | |
| GSE26886 | THAP10 | 56906 | 219596_at | 0.5069 | 0.0377 | |
| GSE29001 | THAP10 | 56906 | 219596_at | 0.5752 | 0.1003 | |
| GSE38129 | THAP10 | 56906 | 219596_at | 0.7854 | 0.0000 | |
| GSE45670 | THAP10 | 56906 | 219596_at | 0.4240 | 0.0356 | |
| GSE53622 | THAP10 | 56906 | 36639 | 0.3192 | 0.0334 | |
| GSE53624 | THAP10 | 56906 | 36639 | 0.7670 | 0.0000 | |
| GSE63941 | THAP10 | 56906 | 219596_at | 0.6576 | 0.3427 | |
| GSE77861 | THAP10 | 56906 | 219596_at | 0.5553 | 0.0601 | |
| GSE97050 | THAP10 | 56906 | A_23_P106391 | 0.4317 | 0.1118 | |
| SRP064894 | THAP10 | 56906 | RNAseq | 0.5296 | 0.0111 | |
| SRP133303 | THAP10 | 56906 | RNAseq | 0.7036 | 0.0401 | |
| SRP159526 | THAP10 | 56906 | RNAseq | 0.1244 | 0.7310 | |
| SRP219564 | THAP10 | 56906 | RNAseq | -0.1498 | 0.6378 | |
| TCGA | THAP10 | 56906 | RNAseq | -0.3278 | 0.0017 |
Upregulated datasets: 1; Downregulated datasets: 0.
Survival by THAP10 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of THAP10:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | THAP10 | 56906 | 7 | 1 | 22 | |
| GSE20123 | THAP10 | 56906 | 7 | 1 | 22 | |
| GSE43470 | THAP10 | 56906 | 4 | 6 | 33 | |
| GSE46452 | THAP10 | 56906 | 3 | 7 | 49 | |
| GSE47630 | THAP10 | 56906 | 8 | 10 | 22 | |
| GSE54993 | THAP10 | 56906 | 5 | 6 | 59 | |
| GSE54994 | THAP10 | 56906 | 5 | 8 | 40 | |
| GSE60625 | THAP10 | 56906 | 4 | 4 | 3 | |
| GSE74703 | THAP10 | 56906 | 4 | 3 | 29 | |
| GSE74704 | THAP10 | 56906 | 3 | 1 | 16 | |
| TCGA | THAP10 | 56906 | 10 | 15 | 71 |
Total number of gains: 60; Total number of losses: 62; Total Number of normals: 366.
Somatic mutations of THAP10:
Generating mutation plots.
Highly correlated genes for THAP10:
Showing top 20/1355 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| THAP10 | SGTB | 0.774984 | 3 | 0 | 3 |
| THAP10 | NTRK2 | 0.768531 | 3 | 0 | 3 |
| THAP10 | ZNF567 | 0.764996 | 3 | 0 | 3 |
| THAP10 | PDPR | 0.748 | 3 | 0 | 3 |
| THAP10 | ERI2 | 0.746329 | 3 | 0 | 3 |
| THAP10 | SPTBN1 | 0.73893 | 4 | 0 | 4 |
| THAP10 | DHRSX | 0.732399 | 3 | 0 | 3 |
| THAP10 | NEK3 | 0.732156 | 3 | 0 | 3 |
| THAP10 | MRPL10 | 0.730745 | 3 | 0 | 3 |
| THAP10 | LETM2 | 0.730701 | 3 | 0 | 3 |
| THAP10 | OAF | 0.720586 | 3 | 0 | 3 |
| THAP10 | C1QBP | 0.717725 | 4 | 0 | 3 |
| THAP10 | HERC2 | 0.71259 | 4 | 0 | 4 |
| THAP10 | XPO4 | 0.703971 | 5 | 0 | 4 |
| THAP10 | ABHD2 | 0.701598 | 5 | 0 | 4 |
| THAP10 | NOM1 | 0.698385 | 4 | 0 | 3 |
| THAP10 | C20orf194 | 0.697764 | 3 | 0 | 3 |
| THAP10 | RNF26 | 0.697251 | 4 | 0 | 3 |
| THAP10 | FAM199X | 0.69585 | 4 | 0 | 4 |
| THAP10 | THEM4 | 0.694003 | 4 | 0 | 3 |
For details and further investigation, click here
