| Full name: follistatin like 3 | Alias Symbol: FLRG|FSRP | ||
| Type: protein-coding gene | Cytoband: 19p13.3 | ||
| Entrez ID: 10272 | HGNC ID: HGNC:3973 | Ensembl Gene: ENSG00000070404 | OMIM ID: 605343 |
| Drug and gene relationship at DGIdb | |||
Expression of FSTL3:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | FSTL3 | 10272 | 203592_s_at | 0.7428 | 0.2180 | |
| GSE20347 | FSTL3 | 10272 | 203592_s_at | 0.7326 | 0.0001 | |
| GSE23400 | FSTL3 | 10272 | 203592_s_at | 0.2843 | 0.0023 | |
| GSE26886 | FSTL3 | 10272 | 203592_s_at | 1.3247 | 0.0000 | |
| GSE29001 | FSTL3 | 10272 | 203592_s_at | 0.7054 | 0.0070 | |
| GSE38129 | FSTL3 | 10272 | 203592_s_at | 0.4412 | 0.0602 | |
| GSE45670 | FSTL3 | 10272 | 203592_s_at | -0.0197 | 0.9421 | |
| GSE53622 | FSTL3 | 10272 | 31513 | 0.2146 | 0.0549 | |
| GSE53624 | FSTL3 | 10272 | 31513 | 0.4171 | 0.0000 | |
| GSE63941 | FSTL3 | 10272 | 203592_s_at | -0.5606 | 0.3204 | |
| GSE77861 | FSTL3 | 10272 | 203592_s_at | 0.3408 | 0.2219 | |
| GSE97050 | FSTL3 | 10272 | A_33_P3318796 | 0.0621 | 0.8515 | |
| SRP007169 | FSTL3 | 10272 | RNAseq | 4.1871 | 0.0000 | |
| SRP008496 | FSTL3 | 10272 | RNAseq | 3.3627 | 0.0000 | |
| SRP064894 | FSTL3 | 10272 | RNAseq | 1.4325 | 0.0000 | |
| SRP133303 | FSTL3 | 10272 | RNAseq | 1.8297 | 0.0000 | |
| SRP159526 | FSTL3 | 10272 | RNAseq | 0.4843 | 0.3694 | |
| SRP193095 | FSTL3 | 10272 | RNAseq | 2.7414 | 0.0000 | |
| TCGA | FSTL3 | 10272 | RNAseq | 0.0915 | 0.5547 |
Upregulated datasets: 6; Downregulated datasets: 0.
Survival by FSTL3 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of FSTL3:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | FSTL3 | 10272 | 4 | 6 | 20 | |
| GSE20123 | FSTL3 | 10272 | 4 | 5 | 21 | |
| GSE43470 | FSTL3 | 10272 | 1 | 10 | 32 | |
| GSE46452 | FSTL3 | 10272 | 47 | 1 | 11 | |
| GSE47630 | FSTL3 | 10272 | 5 | 7 | 28 | |
| GSE54993 | FSTL3 | 10272 | 13 | 4 | 53 | |
| GSE54994 | FSTL3 | 10272 | 8 | 15 | 30 | |
| GSE60625 | FSTL3 | 10272 | 9 | 0 | 2 | |
| GSE74703 | FSTL3 | 10272 | 1 | 7 | 28 | |
| GSE74704 | FSTL3 | 10272 | 3 | 3 | 14 | |
| TCGA | FSTL3 | 10272 | 8 | 25 | 63 |
Total number of gains: 103; Total number of losses: 83; Total Number of normals: 302.
Somatic mutations of FSTL3:
Generating mutation plots.
Highly correlated genes for FSTL3:
Showing top 20/506 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| FSTL3 | PRIM2 | 0.703914 | 3 | 0 | 3 |
| FSTL3 | TBX15 | 0.701292 | 3 | 0 | 3 |
| FSTL3 | SFXN3 | 0.698844 | 9 | 0 | 9 |
| FSTL3 | INHBA | 0.69371 | 11 | 0 | 10 |
| FSTL3 | FARSA | 0.68634 | 3 | 0 | 3 |
| FSTL3 | ACOT9 | 0.681379 | 9 | 0 | 9 |
| FSTL3 | CEP78 | 0.67729 | 3 | 0 | 3 |
| FSTL3 | HSPBAP1 | 0.670349 | 3 | 0 | 3 |
| FSTL3 | ITGA5 | 0.669575 | 11 | 0 | 10 |
| FSTL3 | DNMT1 | 0.66663 | 4 | 0 | 4 |
| FSTL3 | TMC8 | 0.666207 | 3 | 0 | 3 |
| FSTL3 | POU6F2-AS2 | 0.664044 | 3 | 0 | 3 |
| FSTL3 | LOXL1-AS1 | 0.658573 | 3 | 0 | 3 |
| FSTL3 | AGMAT | 0.654208 | 3 | 0 | 3 |
| FSTL3 | COPRS | 0.64993 | 4 | 0 | 3 |
| FSTL3 | TNFRSF12A | 0.649555 | 12 | 0 | 11 |
| FSTL3 | FKBP11 | 0.646676 | 4 | 0 | 3 |
| FSTL3 | FAM189B | 0.645249 | 5 | 0 | 4 |
| FSTL3 | CMC2 | 0.644905 | 4 | 0 | 3 |
| FSTL3 | PMEPA1 | 0.64314 | 13 | 0 | 9 |
For details and further investigation, click here
