| Full name: lipin 1 | Alias Symbol: KIAA0188 | ||
| Type: protein-coding gene | Cytoband: 2p25.1 | ||
| Entrez ID: 23175 | HGNC ID: HGNC:13345 | Ensembl Gene: ENSG00000134324 | OMIM ID: 605518 |
| Drug and gene relationship at DGIdb | |||
Expression of LPIN1:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | LPIN1 | 23175 | 212274_at | -1.1752 | 0.1811 | |
| GSE20347 | LPIN1 | 23175 | 212274_at | -1.5189 | 0.0000 | |
| GSE23400 | LPIN1 | 23175 | 212274_at | -2.1936 | 0.0000 | |
| GSE26886 | LPIN1 | 23175 | 212274_at | -2.8628 | 0.0000 | |
| GSE29001 | LPIN1 | 23175 | 212274_at | -1.5027 | 0.0021 | |
| GSE38129 | LPIN1 | 23175 | 212276_at | -1.7027 | 0.0000 | |
| GSE45670 | LPIN1 | 23175 | 212274_at | -1.2430 | 0.0047 | |
| GSE53622 | LPIN1 | 23175 | 37913 | -3.1387 | 0.0000 | |
| GSE53624 | LPIN1 | 23175 | 55553 | -1.9995 | 0.0000 | |
| GSE63941 | LPIN1 | 23175 | 212276_at | -2.4449 | 0.0076 | |
| GSE77861 | LPIN1 | 23175 | 212276_at | -2.2237 | 0.0009 | |
| GSE97050 | LPIN1 | 23175 | A_33_P3356075 | -0.8599 | 0.1403 | |
| SRP007169 | LPIN1 | 23175 | RNAseq | -4.0549 | 0.0000 | |
| SRP008496 | LPIN1 | 23175 | RNAseq | -3.8580 | 0.0000 | |
| SRP064894 | LPIN1 | 23175 | RNAseq | -3.5497 | 0.0000 | |
| SRP133303 | LPIN1 | 23175 | RNAseq | -2.1793 | 0.0000 | |
| SRP159526 | LPIN1 | 23175 | RNAseq | -1.6160 | 0.0000 | |
| SRP193095 | LPIN1 | 23175 | RNAseq | -2.7176 | 0.0000 | |
| SRP219564 | LPIN1 | 23175 | RNAseq | -1.2954 | 0.0825 | |
| TCGA | LPIN1 | 23175 | RNAseq | -0.2140 | 0.0112 |
Upregulated datasets: 0; Downregulated datasets: 16.
Survival by LPIN1 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of LPIN1:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | LPIN1 | 23175 | 10 | 2 | 18 | |
| GSE20123 | LPIN1 | 23175 | 10 | 2 | 18 | |
| GSE43470 | LPIN1 | 23175 | 2 | 1 | 40 | |
| GSE46452 | LPIN1 | 23175 | 3 | 4 | 52 | |
| GSE47630 | LPIN1 | 23175 | 7 | 0 | 33 | |
| GSE54993 | LPIN1 | 23175 | 0 | 7 | 63 | |
| GSE54994 | LPIN1 | 23175 | 11 | 0 | 42 | |
| GSE60625 | LPIN1 | 23175 | 0 | 3 | 8 | |
| GSE74703 | LPIN1 | 23175 | 2 | 0 | 34 | |
| GSE74704 | LPIN1 | 23175 | 9 | 1 | 10 | |
| TCGA | LPIN1 | 23175 | 34 | 5 | 57 |
Total number of gains: 88; Total number of losses: 25; Total Number of normals: 375.
Somatic mutations of LPIN1:
Generating mutation plots.
Highly correlated genes for LPIN1:
Showing top 20/1292 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| LPIN1 | UPK3B | 0.842371 | 3 | 0 | 3 |
| LPIN1 | VSIG10L | 0.839092 | 7 | 0 | 7 |
| LPIN1 | C5orf66-AS1 | 0.838211 | 5 | 0 | 5 |
| LPIN1 | VSIG2 | 0.83724 | 6 | 0 | 6 |
| LPIN1 | FAM214A | 0.828845 | 6 | 0 | 5 |
| LPIN1 | SH3BGRL2 | 0.825458 | 7 | 0 | 7 |
| LPIN1 | GYS2 | 0.824787 | 10 | 0 | 10 |
| LPIN1 | ATG9B | 0.822136 | 7 | 0 | 7 |
| LPIN1 | FAM3B | 0.819575 | 5 | 0 | 5 |
| LPIN1 | UPK1A | 0.818668 | 11 | 0 | 11 |
| LPIN1 | TMPRSS11B | 0.817338 | 7 | 0 | 7 |
| LPIN1 | FAM3D | 0.817287 | 7 | 0 | 6 |
| LPIN1 | KLB | 0.816057 | 5 | 0 | 5 |
| LPIN1 | NCCRP1 | 0.814521 | 3 | 0 | 3 |
| LPIN1 | GDPD3 | 0.814254 | 11 | 0 | 10 |
| LPIN1 | IL36A | 0.804565 | 11 | 0 | 10 |
| LPIN1 | UBL3 | 0.801435 | 11 | 0 | 10 |
| LPIN1 | YOD1 | 0.799352 | 10 | 0 | 10 |
| LPIN1 | A2ML1 | 0.797592 | 7 | 0 | 6 |
| LPIN1 | SPNS2 | 0.796693 | 5 | 0 | 5 |
For details and further investigation, click here
