| Full name: glucosidase alpha, neutral C | Alias Symbol: | ||
| Type: protein-coding gene | Cytoband: 15q15.1 | ||
| Entrez ID: 2595 | HGNC ID: HGNC:4139 | Ensembl Gene: ENSG00000214013 | OMIM ID: 104180 |
| Drug and gene relationship at DGIdb | |||
Expression of GANC:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | GANC | 2595 | 236077_at | -0.6139 | 0.2596 | |
| GSE26886 | GANC | 2595 | 236077_at | -1.1646 | 0.0001 | |
| GSE45670 | GANC | 2595 | 236077_at | -0.4577 | 0.0343 | |
| GSE53622 | GANC | 2595 | 25843 | -1.2031 | 0.0000 | |
| GSE53624 | GANC | 2595 | 25843 | -1.1957 | 0.0000 | |
| GSE63941 | GANC | 2595 | 236077_at | -0.8097 | 0.0919 | |
| GSE77861 | GANC | 2595 | 236077_at | -0.8863 | 0.0301 | |
| GSE97050 | GANC | 2595 | A_33_P3295108 | -0.3756 | 0.2454 | |
| SRP007169 | GANC | 2595 | RNAseq | -1.1062 | 0.0160 | |
| SRP008496 | GANC | 2595 | RNAseq | -1.5105 | 0.0000 | |
| SRP064894 | GANC | 2595 | RNAseq | -0.7751 | 0.0000 | |
| SRP133303 | GANC | 2595 | RNAseq | -0.5549 | 0.0019 | |
| SRP159526 | GANC | 2595 | RNAseq | -1.1963 | 0.0000 | |
| SRP193095 | GANC | 2595 | RNAseq | -0.4371 | 0.0011 | |
| SRP219564 | GANC | 2595 | RNAseq | -0.7378 | 0.0691 | |
| TCGA | GANC | 2595 | RNAseq | -0.0066 | 0.9184 |
Upregulated datasets: 0; Downregulated datasets: 6.
Survival by GANC expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of GANC:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | GANC | 2595 | 4 | 5 | 21 | |
| GSE20123 | GANC | 2595 | 4 | 6 | 20 | |
| GSE43470 | GANC | 2595 | 4 | 5 | 34 | |
| GSE46452 | GANC | 2595 | 3 | 7 | 49 | |
| GSE47630 | GANC | 2595 | 8 | 11 | 21 | |
| GSE54993 | GANC | 2595 | 4 | 6 | 60 | |
| GSE54994 | GANC | 2595 | 5 | 7 | 41 | |
| GSE60625 | GANC | 2595 | 4 | 0 | 7 | |
| GSE74703 | GANC | 2595 | 4 | 4 | 28 | |
| GSE74704 | GANC | 2595 | 3 | 3 | 14 | |
| TCGA | GANC | 2595 | 11 | 18 | 67 |
Total number of gains: 54; Total number of losses: 72; Total Number of normals: 362.
Somatic mutations of GANC:
Generating mutation plots.
Highly correlated genes for GANC:
Showing top 20/1335 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| GANC | PALMD | 0.77554 | 7 | 0 | 7 |
| GANC | NLRX1 | 0.747208 | 6 | 0 | 6 |
| GANC | TPD52L2 | 0.745797 | 3 | 0 | 3 |
| GANC | KCMF1 | 0.74268 | 3 | 0 | 3 |
| GANC | PDLIM2 | 0.738105 | 6 | 0 | 6 |
| GANC | HUS1 | 0.73213 | 3 | 0 | 3 |
| GANC | RALB | 0.731145 | 4 | 0 | 4 |
| GANC | CCNYL1 | 0.730953 | 6 | 0 | 5 |
| GANC | FCHO2 | 0.727394 | 7 | 0 | 7 |
| GANC | SLC12A6 | 0.726457 | 4 | 0 | 4 |
| GANC | CA13 | 0.726342 | 3 | 0 | 3 |
| GANC | RAB11A | 0.725981 | 7 | 0 | 6 |
| GANC | CNN3 | 0.723209 | 5 | 0 | 5 |
| GANC | MXD1 | 0.722743 | 6 | 0 | 6 |
| GANC | GDPD3 | 0.721744 | 6 | 0 | 6 |
| GANC | CYSRT1 | 0.721023 | 6 | 0 | 6 |
| GANC | VPS37B | 0.720375 | 6 | 0 | 6 |
| GANC | CWH43 | 0.719826 | 6 | 0 | 6 |
| GANC | MAP2K1 | 0.718013 | 7 | 0 | 7 |
| GANC | MTF1 | 0.717637 | 5 | 0 | 5 |
For details and further investigation, click here
