| Full name: glucosaminyl (N-acetyl) transferase 3, mucin type | Alias Symbol: C2GnT-M|C2/4GnT|C2GnT2 | ||
| Type: protein-coding gene | Cytoband: 15q22.2 | ||
| Entrez ID: 9245 | HGNC ID: HGNC:4205 | Ensembl Gene: ENSG00000140297 | OMIM ID: 606836 |
| Drug and gene relationship at DGIdb | |||
Expression of GCNT3:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | GCNT3 | 9245 | 219508_at | -1.3441 | 0.2542 | |
| GSE20347 | GCNT3 | 9245 | 219508_at | -1.3333 | 0.0000 | |
| GSE23400 | GCNT3 | 9245 | 219508_at | -0.8734 | 0.0000 | |
| GSE26886 | GCNT3 | 9245 | 219508_at | -3.4412 | 0.0000 | |
| GSE29001 | GCNT3 | 9245 | 219508_at | -2.2643 | 0.0008 | |
| GSE38129 | GCNT3 | 9245 | 219508_at | -1.1037 | 0.0015 | |
| GSE45670 | GCNT3 | 9245 | 219508_at | -1.2333 | 0.0117 | |
| GSE53622 | GCNT3 | 9245 | 2140 | -2.9618 | 0.0000 | |
| GSE53624 | GCNT3 | 9245 | 2140 | -3.3904 | 0.0000 | |
| GSE63941 | GCNT3 | 9245 | 219508_at | 1.5009 | 0.4030 | |
| GSE77861 | GCNT3 | 9245 | 219508_at | -1.0823 | 0.0757 | |
| GSE97050 | GCNT3 | 9245 | A_23_P420209 | -0.3614 | 0.4276 | |
| SRP007169 | GCNT3 | 9245 | RNAseq | -2.0426 | 0.0298 | |
| SRP008496 | GCNT3 | 9245 | RNAseq | -2.7827 | 0.0031 | |
| SRP064894 | GCNT3 | 9245 | RNAseq | -2.8184 | 0.0000 | |
| SRP133303 | GCNT3 | 9245 | RNAseq | -1.1170 | 0.0012 | |
| SRP159526 | GCNT3 | 9245 | RNAseq | -2.4768 | 0.0035 | |
| SRP193095 | GCNT3 | 9245 | RNAseq | -0.9169 | 0.0049 | |
| SRP219564 | GCNT3 | 9245 | RNAseq | -2.5553 | 0.0081 | |
| TCGA | GCNT3 | 9245 | RNAseq | -0.7028 | 0.0661 |
Upregulated datasets: 0; Downregulated datasets: 13.
Survival by GCNT3 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of GCNT3:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | GCNT3 | 9245 | 6 | 4 | 20 | |
| GSE20123 | GCNT3 | 9245 | 6 | 3 | 21 | |
| GSE43470 | GCNT3 | 9245 | 4 | 4 | 35 | |
| GSE46452 | GCNT3 | 9245 | 3 | 7 | 49 | |
| GSE47630 | GCNT3 | 9245 | 8 | 10 | 22 | |
| GSE54993 | GCNT3 | 9245 | 5 | 6 | 59 | |
| GSE54994 | GCNT3 | 9245 | 6 | 8 | 39 | |
| GSE60625 | GCNT3 | 9245 | 4 | 0 | 7 | |
| GSE74703 | GCNT3 | 9245 | 4 | 3 | 29 | |
| GSE74704 | GCNT3 | 9245 | 2 | 3 | 15 | |
| TCGA | GCNT3 | 9245 | 10 | 17 | 69 |
Total number of gains: 58; Total number of losses: 65; Total Number of normals: 365.
Somatic mutations of GCNT3:
Generating mutation plots.
Highly correlated genes for GCNT3:
Showing top 20/1269 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| GCNT3 | CEACAM5 | 0.788117 | 13 | 0 | 13 |
| GCNT3 | LIPH | 0.78719 | 8 | 0 | 7 |
| GCNT3 | GDPD3 | 0.778308 | 11 | 0 | 11 |
| GCNT3 | FAM3D | 0.776034 | 9 | 0 | 8 |
| GCNT3 | SMIM5 | 0.773154 | 6 | 0 | 6 |
| GCNT3 | SDCBP2 | 0.773073 | 3 | 0 | 3 |
| GCNT3 | TPRG1 | 0.772874 | 6 | 0 | 6 |
| GCNT3 | CEACAM6 | 0.770248 | 13 | 0 | 13 |
| GCNT3 | UPK3B | 0.769633 | 3 | 0 | 3 |
| GCNT3 | SMAGP | 0.762693 | 12 | 0 | 11 |
| GCNT3 | KRT78 | 0.762081 | 7 | 0 | 7 |
| GCNT3 | CAPN14 | 0.760922 | 6 | 0 | 6 |
| GCNT3 | TTC9 | 0.759293 | 12 | 0 | 12 |
| GCNT3 | EVPL | 0.755727 | 11 | 0 | 11 |
| GCNT3 | CEACAM1 | 0.752672 | 11 | 0 | 11 |
| GCNT3 | PAX9 | 0.752349 | 13 | 0 | 13 |
| GCNT3 | FUT3 | 0.750377 | 13 | 0 | 13 |
| GCNT3 | ATP13A4 | 0.747655 | 8 | 0 | 7 |
| GCNT3 | BNIPL | 0.747212 | 7 | 0 | 7 |
| GCNT3 | POF1B | 0.746662 | 11 | 0 | 11 |
For details and further investigation, click here
