| Full name: C9orf72-SMCR8 complex subunit | Alias Symbol: MGC23980|DENNL72|DENND9 | ||
| Type: protein-coding gene | Cytoband: 9p21.2 | ||
| Entrez ID: 203228 | HGNC ID: HGNC:28337 | Ensembl Gene: ENSG00000147894 | OMIM ID: 614260 |
Expression of C9orf72:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | C9orf72 | 203228 | 225919_s_at | -0.3430 | 0.5062 | |
| GSE26886 | C9orf72 | 203228 | 225919_s_at | -0.6887 | 0.0232 | |
| GSE45670 | C9orf72 | 203228 | 225919_s_at | -0.6341 | 0.0626 | |
| GSE53622 | C9orf72 | 203228 | 17039 | -0.2504 | 0.0029 | |
| GSE53624 | C9orf72 | 203228 | 17039 | -0.4531 | 0.0000 | |
| GSE63941 | C9orf72 | 203228 | 225919_s_at | -0.2075 | 0.7631 | |
| GSE77861 | C9orf72 | 203228 | 225919_s_at | 0.0303 | 0.9724 | |
| GSE97050 | C9orf72 | 203228 | A_23_P405873 | -0.0252 | 0.9224 | |
| SRP007169 | C9orf72 | 203228 | RNAseq | -0.6176 | 0.1843 | |
| SRP008496 | C9orf72 | 203228 | RNAseq | -0.3108 | 0.4009 | |
| SRP064894 | C9orf72 | 203228 | RNAseq | -0.4286 | 0.1842 | |
| SRP133303 | C9orf72 | 203228 | RNAseq | -0.0880 | 0.6683 | |
| SRP159526 | C9orf72 | 203228 | RNAseq | -0.5824 | 0.1169 | |
| SRP193095 | C9orf72 | 203228 | RNAseq | -0.4976 | 0.0036 | |
| SRP219564 | C9orf72 | 203228 | RNAseq | -0.5006 | 0.1480 | |
| TCGA | C9orf72 | 203228 | RNAseq | -0.1858 | 0.0960 |
Upregulated datasets: 0; Downregulated datasets: 0.
Survival by C9orf72 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of C9orf72:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | C9orf72 | 203228 | 2 | 14 | 14 | |
| GSE20123 | C9orf72 | 203228 | 2 | 14 | 14 | |
| GSE43470 | C9orf72 | 203228 | 1 | 11 | 31 | |
| GSE46452 | C9orf72 | 203228 | 6 | 18 | 35 | |
| GSE47630 | C9orf72 | 203228 | 1 | 22 | 17 | |
| GSE54993 | C9orf72 | 203228 | 7 | 0 | 63 | |
| GSE54994 | C9orf72 | 203228 | 7 | 14 | 32 | |
| GSE60625 | C9orf72 | 203228 | 0 | 0 | 11 | |
| GSE74703 | C9orf72 | 203228 | 1 | 8 | 27 | |
| GSE74704 | C9orf72 | 203228 | 0 | 11 | 9 | |
| TCGA | C9orf72 | 203228 | 15 | 46 | 35 |
Total number of gains: 42; Total number of losses: 158; Total Number of normals: 288.
Somatic mutations of C9orf72:
Generating mutation plots.
Highly correlated genes for C9orf72:
Showing top 20/205 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| C9orf72 | ZNF215 | 0.79316 | 3 | 0 | 3 |
| C9orf72 | CHUK | 0.745855 | 3 | 0 | 3 |
| C9orf72 | LMCD1 | 0.742714 | 3 | 0 | 3 |
| C9orf72 | TFPI | 0.725574 | 4 | 0 | 3 |
| C9orf72 | SATB1 | 0.724923 | 3 | 0 | 3 |
| C9orf72 | LRRC55 | 0.723926 | 3 | 0 | 3 |
| C9orf72 | EIF3L | 0.71814 | 3 | 0 | 3 |
| C9orf72 | MAP3K8 | 0.709206 | 4 | 0 | 3 |
| C9orf72 | CRNKL1 | 0.705755 | 3 | 0 | 3 |
| C9orf72 | IGFBP5 | 0.705684 | 3 | 0 | 3 |
| C9orf72 | SLC38A5 | 0.700666 | 3 | 0 | 3 |
| C9orf72 | MSI2 | 0.69772 | 3 | 0 | 3 |
| C9orf72 | APPL1 | 0.687104 | 3 | 0 | 3 |
| C9orf72 | POLI | 0.684117 | 4 | 0 | 4 |
| C9orf72 | SMAD5 | 0.681528 | 3 | 0 | 3 |
| C9orf72 | TMEM150C | 0.677349 | 4 | 0 | 3 |
| C9orf72 | CAAP1 | 0.67207 | 6 | 0 | 5 |
| C9orf72 | SLC12A6 | 0.670131 | 3 | 0 | 3 |
| C9orf72 | NOTCH2 | 0.669735 | 4 | 0 | 4 |
| C9orf72 | LARP7 | 0.668823 | 3 | 0 | 3 |
For details and further investigation, click here
