| Full name: leucine rich repeat containing 56 | Alias Symbol: FLJ00101|DKFZp761L1518 | ||
| Type: protein-coding gene | Cytoband: 11p15.5 | ||
| Entrez ID: 115399 | HGNC ID: HGNC:25430 | Ensembl Gene: ENSG00000161328 | OMIM ID: 618227 |
| Drug and gene relationship at DGIdb | |||
Expression of LRRC56:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | LRRC56 | 115399 | 232554_at | 0.0766 | 0.7655 | |
| GSE26886 | LRRC56 | 115399 | 232554_at | 0.3321 | 0.0063 | |
| GSE45670 | LRRC56 | 115399 | 232554_at | 0.0978 | 0.3735 | |
| GSE53622 | LRRC56 | 115399 | 92023 | -0.5472 | 0.0010 | |
| GSE53624 | LRRC56 | 115399 | 92023 | -0.2627 | 0.0058 | |
| GSE63941 | LRRC56 | 115399 | 232554_at | -0.0570 | 0.7741 | |
| GSE77861 | LRRC56 | 115399 | 232554_at | -0.1464 | 0.3117 | |
| GSE97050 | LRRC56 | 115399 | A_23_P368996 | 0.0682 | 0.7683 | |
| SRP064894 | LRRC56 | 115399 | RNAseq | 0.1959 | 0.5427 | |
| SRP133303 | LRRC56 | 115399 | RNAseq | -0.4347 | 0.1704 | |
| SRP159526 | LRRC56 | 115399 | RNAseq | -1.0048 | 0.0070 | |
| SRP193095 | LRRC56 | 115399 | RNAseq | -0.1086 | 0.5653 | |
| SRP219564 | LRRC56 | 115399 | RNAseq | 0.2951 | 0.6363 | |
| TCGA | LRRC56 | 115399 | RNAseq | -0.0805 | 0.6295 |
Upregulated datasets: 0; Downregulated datasets: 1.
Survival by LRRC56 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of LRRC56:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | LRRC56 | 115399 | 1 | 11 | 18 | |
| GSE20123 | LRRC56 | 115399 | 1 | 12 | 17 | |
| GSE43470 | LRRC56 | 115399 | 1 | 10 | 32 | |
| GSE46452 | LRRC56 | 115399 | 7 | 8 | 44 | |
| GSE47630 | LRRC56 | 115399 | 4 | 12 | 24 | |
| GSE54993 | LRRC56 | 115399 | 3 | 2 | 65 | |
| GSE54994 | LRRC56 | 115399 | 1 | 12 | 40 | |
| GSE60625 | LRRC56 | 115399 | 0 | 0 | 11 | |
| GSE74703 | LRRC56 | 115399 | 1 | 8 | 27 | |
| GSE74704 | LRRC56 | 115399 | 0 | 8 | 12 | |
| TCGA | LRRC56 | 115399 | 8 | 38 | 50 |
Total number of gains: 27; Total number of losses: 121; Total Number of normals: 340.
Somatic mutations of LRRC56:
Generating mutation plots.
Highly correlated genes for LRRC56:
Showing top 20/175 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| LRRC56 | SH3BP2 | 0.763528 | 3 | 0 | 3 |
| LRRC56 | SUGP1 | 0.71762 | 4 | 0 | 4 |
| LRRC56 | REC8 | 0.711596 | 3 | 0 | 3 |
| LRRC56 | ALKBH6 | 0.700659 | 3 | 0 | 3 |
| LRRC56 | SLC25A29 | 0.693404 | 3 | 0 | 3 |
| LRRC56 | GATA3 | 0.68825 | 3 | 0 | 3 |
| LRRC56 | BRD4 | 0.688199 | 3 | 0 | 3 |
| LRRC56 | CHD7 | 0.684008 | 3 | 0 | 3 |
| LRRC56 | TMEM222 | 0.673902 | 3 | 0 | 3 |
| LRRC56 | CDK18 | 0.671958 | 3 | 0 | 3 |
| LRRC56 | RAB42 | 0.670527 | 3 | 0 | 3 |
| LRRC56 | RAB11B | 0.669854 | 3 | 0 | 3 |
| LRRC56 | PAQR4 | 0.669281 | 3 | 0 | 3 |
| LRRC56 | LY9 | 0.666149 | 3 | 0 | 3 |
| LRRC56 | LIMK1 | 0.665265 | 3 | 0 | 3 |
| LRRC56 | RNF208 | 0.663651 | 4 | 0 | 3 |
| LRRC56 | PLEKHG6 | 0.662182 | 3 | 0 | 3 |
| LRRC56 | SAMD1 | 0.662161 | 4 | 0 | 4 |
| LRRC56 | BARX2 | 0.66057 | 3 | 0 | 3 |
| LRRC56 | CLMN | 0.65996 | 4 | 0 | 4 |
For details and further investigation, click here
