| Full name: leucine rich repeat containing 66 | Alias Symbol: | ||
| Type: protein-coding gene | Cytoband: 4q12 | ||
| Entrez ID: 339977 | HGNC ID: HGNC:34299 | Ensembl Gene: ENSG00000188993 | OMIM ID: |
| Drug and gene relationship at DGIdb | |||
Expression of LRRC66:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | LRRC66 | 339977 | 1568634_a_at | -0.0322 | 0.9307 | |
| GSE26886 | LRRC66 | 339977 | 1568634_a_at | -0.0126 | 0.9056 | |
| GSE45670 | LRRC66 | 339977 | 1568634_a_at | -0.0388 | 0.6946 | |
| GSE53622 | LRRC66 | 339977 | 102919 | -0.2477 | 0.1488 | |
| GSE53624 | LRRC66 | 339977 | 102919 | -0.2522 | 0.0780 | |
| GSE63941 | LRRC66 | 339977 | 1568634_a_at | -0.8263 | 0.0000 | |
| GSE77861 | LRRC66 | 339977 | 1568634_a_at | -0.1430 | 0.0601 | |
| SRP133303 | LRRC66 | 339977 | RNAseq | -0.0150 | 0.9638 | |
| TCGA | LRRC66 | 339977 | RNAseq | -2.4606 | 0.0000 |
Upregulated datasets: 0; Downregulated datasets: 1.
Survival by LRRC66 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of LRRC66:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | LRRC66 | 339977 | 4 | 11 | 15 | |
| GSE20123 | LRRC66 | 339977 | 3 | 11 | 16 | |
| GSE43470 | LRRC66 | 339977 | 0 | 14 | 29 | |
| GSE46452 | LRRC66 | 339977 | 1 | 36 | 22 | |
| GSE47630 | LRRC66 | 339977 | 1 | 18 | 21 | |
| GSE54993 | LRRC66 | 339977 | 7 | 0 | 63 | |
| GSE54994 | LRRC66 | 339977 | 2 | 10 | 41 | |
| GSE60625 | LRRC66 | 339977 | 0 | 0 | 11 | |
| GSE74703 | LRRC66 | 339977 | 0 | 12 | 24 | |
| GSE74704 | LRRC66 | 339977 | 2 | 6 | 12 | |
| TCGA | LRRC66 | 339977 | 17 | 29 | 50 |
Total number of gains: 37; Total number of losses: 147; Total Number of normals: 304.
Somatic mutations of LRRC66:
Generating mutation plots.
Highly correlated genes for LRRC66:
Showing all 17 correlated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| LRRC66 | MCOLN2 | 0.648097 | 3 | 0 | 3 |
| LRRC66 | SMPDL3A | 0.647054 | 3 | 0 | 3 |
| LRRC66 | HLA-DPB1 | 0.634495 | 3 | 0 | 3 |
| LRRC66 | VPS9D1 | 0.625903 | 3 | 0 | 3 |
| LRRC66 | CD2 | 0.624161 | 3 | 0 | 3 |
| LRRC66 | MYO1A | 0.610561 | 3 | 0 | 3 |
| LRRC66 | GYPC | 0.602523 | 3 | 0 | 3 |
| LRRC66 | SPATA9 | 0.599643 | 3 | 0 | 3 |
| LRRC66 | TCERG1L | 0.596263 | 3 | 0 | 3 |
| LRRC66 | CTSE | 0.587196 | 4 | 0 | 3 |
| LRRC66 | GBE1 | 0.582735 | 3 | 0 | 3 |
| LRRC66 | DOCK10 | 0.57835 | 3 | 0 | 3 |
| LRRC66 | HIPK2 | 0.56878 | 3 | 0 | 3 |
| LRRC66 | HLA-DQB2 | 0.5652 | 3 | 0 | 3 |
| LRRC66 | RAB2A | 0.553285 | 3 | 0 | 3 |
| LRRC66 | C4BPB | 0.552029 | 3 | 0 | 3 |
| LRRC66 | STS | 0.503207 | 4 | 0 | 3 |
For details and further investigation, click here
