| Full name: mucolipin 2 | Alias Symbol: TRPML2|FLJ36691|TRP-ML2 | ||
| Type: protein-coding gene | Cytoband: 1p22.3 | ||
| Entrez ID: 255231 | HGNC ID: HGNC:13357 | Ensembl Gene: ENSG00000153898 | OMIM ID: 607399 |
| Drug and gene relationship at DGIdb | |||
Expression of MCOLN2:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | MCOLN2 | 255231 | 230110_at | 0.2560 | 0.8123 | |
| GSE26886 | MCOLN2 | 255231 | 230110_at | -0.4693 | 0.0556 | |
| GSE45670 | MCOLN2 | 255231 | 230110_at | -0.0278 | 0.9079 | |
| GSE53622 | MCOLN2 | 255231 | 134835 | 0.2682 | 0.0913 | |
| GSE53624 | MCOLN2 | 255231 | 134835 | 0.0149 | 0.9207 | |
| GSE63941 | MCOLN2 | 255231 | 230110_at | -1.9803 | 0.0070 | |
| GSE77861 | MCOLN2 | 255231 | 1555465_at | -0.1332 | 0.1019 | |
| GSE97050 | MCOLN2 | 255231 | A_23_P23639 | 0.5040 | 0.1965 | |
| SRP007169 | MCOLN2 | 255231 | RNAseq | -0.4150 | 0.5974 | |
| SRP064894 | MCOLN2 | 255231 | RNAseq | -0.0427 | 0.8806 | |
| SRP133303 | MCOLN2 | 255231 | RNAseq | -0.0590 | 0.7650 | |
| SRP159526 | MCOLN2 | 255231 | RNAseq | -0.9326 | 0.1963 | |
| SRP193095 | MCOLN2 | 255231 | RNAseq | -0.0386 | 0.8363 | |
| SRP219564 | MCOLN2 | 255231 | RNAseq | 0.0074 | 0.9903 | |
| TCGA | MCOLN2 | 255231 | RNAseq | 0.2066 | 0.4632 |
Upregulated datasets: 0; Downregulated datasets: 1.
Survival by MCOLN2 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of MCOLN2:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | MCOLN2 | 255231 | 0 | 8 | 22 | |
| GSE20123 | MCOLN2 | 255231 | 0 | 8 | 22 | |
| GSE43470 | MCOLN2 | 255231 | 2 | 2 | 39 | |
| GSE46452 | MCOLN2 | 255231 | 0 | 1 | 58 | |
| GSE47630 | MCOLN2 | 255231 | 8 | 5 | 27 | |
| GSE54993 | MCOLN2 | 255231 | 0 | 0 | 70 | |
| GSE54994 | MCOLN2 | 255231 | 6 | 3 | 44 | |
| GSE60625 | MCOLN2 | 255231 | 0 | 0 | 11 | |
| GSE74703 | MCOLN2 | 255231 | 1 | 2 | 33 | |
| GSE74704 | MCOLN2 | 255231 | 0 | 5 | 15 | |
| TCGA | MCOLN2 | 255231 | 7 | 23 | 66 |
Total number of gains: 24; Total number of losses: 57; Total Number of normals: 407.
Somatic mutations of MCOLN2:
Generating mutation plots.
Highly correlated genes for MCOLN2:
Showing top 20/116 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| MCOLN2 | MAP4K1 | 0.702481 | 4 | 0 | 3 |
| MCOLN2 | CFB | 0.685239 | 3 | 0 | 3 |
| MCOLN2 | PSMB8-AS1 | 0.681442 | 3 | 0 | 3 |
| MCOLN2 | BEND6 | 0.67752 | 3 | 0 | 3 |
| MCOLN2 | ITGB2-AS1 | 0.677058 | 4 | 0 | 3 |
| MCOLN2 | SNX20 | 0.652399 | 6 | 0 | 6 |
| MCOLN2 | ITGA4 | 0.650575 | 4 | 0 | 4 |
| MCOLN2 | LRRC66 | 0.648097 | 3 | 0 | 3 |
| MCOLN2 | AKNA | 0.640542 | 4 | 0 | 3 |
| MCOLN2 | HSH2D | 0.637508 | 4 | 0 | 3 |
| MCOLN2 | GPR171 | 0.627186 | 5 | 0 | 4 |
| MCOLN2 | DSPP | 0.627038 | 3 | 0 | 3 |
| MCOLN2 | CD48 | 0.62638 | 8 | 0 | 7 |
| MCOLN2 | STAT3 | 0.625126 | 3 | 0 | 3 |
| MCOLN2 | CD3E | 0.623794 | 5 | 0 | 4 |
| MCOLN2 | SLA2 | 0.623593 | 4 | 0 | 3 |
| MCOLN2 | KLRB1 | 0.622731 | 5 | 0 | 3 |
| MCOLN2 | IL21R | 0.621533 | 7 | 0 | 5 |
| MCOLN2 | IL12A | 0.620856 | 3 | 0 | 3 |
| MCOLN2 | BIN2 | 0.609247 | 4 | 0 | 3 |
For details and further investigation, click here
