| Full name: leucine rich repeat transmembrane neuronal 2 | Alias Symbol: KIAA0416 | ||
| Type: protein-coding gene | Cytoband: 5q31.2 | ||
| Entrez ID: 26045 | HGNC ID: HGNC:19409 | Ensembl Gene: ENSG00000146006 | OMIM ID: 610868 |
| Drug and gene relationship at DGIdb | |||
Expression of LRRTM2:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | LRRTM2 | 26045 | 206408_at | -0.1744 | 0.3202 | |
| GSE20347 | LRRTM2 | 26045 | 206408_at | 0.2832 | 0.0086 | |
| GSE23400 | LRRTM2 | 26045 | 206408_at | -0.0706 | 0.0378 | |
| GSE26886 | LRRTM2 | 26045 | 206408_at | 0.4631 | 0.0016 | |
| GSE29001 | LRRTM2 | 26045 | 206408_at | -0.0058 | 0.9818 | |
| GSE38129 | LRRTM2 | 26045 | 206408_at | 0.1692 | 0.3570 | |
| GSE45670 | LRRTM2 | 26045 | 206408_at | 0.1056 | 0.4355 | |
| GSE53622 | LRRTM2 | 26045 | 55507 | 0.1140 | 0.3002 | |
| GSE53624 | LRRTM2 | 26045 | 55507 | -0.1973 | 0.0200 | |
| GSE63941 | LRRTM2 | 26045 | 206408_at | -0.1901 | 0.3195 | |
| GSE77861 | LRRTM2 | 26045 | 206408_at | -0.1050 | 0.1796 | |
| GSE97050 | LRRTM2 | 26045 | A_24_P140569 | -0.2103 | 0.5537 | |
| SRP007169 | LRRTM2 | 26045 | RNAseq | 1.0046 | 0.2289 | |
| SRP133303 | LRRTM2 | 26045 | RNAseq | 0.3424 | 0.2770 | |
| SRP193095 | LRRTM2 | 26045 | RNAseq | -0.4186 | 0.0345 | |
| TCGA | LRRTM2 | 26045 | RNAseq | -0.1712 | 0.4390 |
Upregulated datasets: 0; Downregulated datasets: 0.
Survival by LRRTM2 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of LRRTM2:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | LRRTM2 | 26045 | 3 | 11 | 16 | |
| GSE20123 | LRRTM2 | 26045 | 4 | 11 | 15 | |
| GSE43470 | LRRTM2 | 26045 | 4 | 5 | 34 | |
| GSE46452 | LRRTM2 | 26045 | 0 | 27 | 32 | |
| GSE47630 | LRRTM2 | 26045 | 0 | 21 | 19 | |
| GSE54993 | LRRTM2 | 26045 | 9 | 1 | 60 | |
| GSE54994 | LRRTM2 | 26045 | 3 | 13 | 37 | |
| GSE60625 | LRRTM2 | 26045 | 0 | 0 | 11 | |
| GSE74703 | LRRTM2 | 26045 | 3 | 4 | 29 | |
| GSE74704 | LRRTM2 | 26045 | 3 | 5 | 12 | |
| TCGA | LRRTM2 | 26045 | 3 | 37 | 56 |
Total number of gains: 32; Total number of losses: 135; Total Number of normals: 321.
Somatic mutations of LRRTM2:
Generating mutation plots.
Highly correlated genes for LRRTM2:
Showing top 20/132 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| LRRTM2 | RGN | 0.718719 | 4 | 0 | 4 |
| LRRTM2 | WIPF3 | 0.703137 | 3 | 0 | 3 |
| LRRTM2 | RXRG | 0.696139 | 3 | 0 | 3 |
| LRRTM2 | MTIF3 | 0.677442 | 3 | 0 | 3 |
| LRRTM2 | CACNG5 | 0.675902 | 3 | 0 | 3 |
| LRRTM2 | CCDC30 | 0.673312 | 5 | 0 | 4 |
| LRRTM2 | RCVRN | 0.671766 | 4 | 0 | 3 |
| LRRTM2 | HSPB6 | 0.666005 | 3 | 0 | 3 |
| LRRTM2 | ZNF33B | 0.665983 | 4 | 0 | 4 |
| LRRTM2 | DAPK1 | 0.661332 | 3 | 0 | 3 |
| LRRTM2 | PRDM5 | 0.660686 | 3 | 0 | 3 |
| LRRTM2 | ZNF287 | 0.658288 | 3 | 0 | 3 |
| LRRTM2 | YTHDC2 | 0.649669 | 3 | 0 | 3 |
| LRRTM2 | PLXNA4 | 0.639178 | 3 | 0 | 3 |
| LRRTM2 | ART4 | 0.636897 | 4 | 0 | 3 |
| LRRTM2 | NRXN2 | 0.629597 | 5 | 0 | 4 |
| LRRTM2 | PLCB1 | 0.621819 | 3 | 0 | 3 |
| LRRTM2 | CRHR2 | 0.620586 | 3 | 0 | 3 |
| LRRTM2 | EXD3 | 0.620322 | 3 | 0 | 3 |
| LRRTM2 | ELSPBP1 | 0.618282 | 3 | 0 | 3 |
For details and further investigation, click here
