| Full name: LSM6 homolog, U6 small nuclear RNA and mRNA degradation associated | Alias Symbol: YDR378C | ||
| Type: protein-coding gene | Cytoband: 4q31.22 | ||
| Entrez ID: 11157 | HGNC ID: HGNC:17017 | Ensembl Gene: ENSG00000164167 | OMIM ID: 607286 |
| Drug and gene relationship at DGIdb | |||
Expression of LSM6:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | LSM6 | 11157 | 205036_at | 0.6139 | 0.0275 | |
| GSE20347 | LSM6 | 11157 | 205036_at | 0.4096 | 0.0015 | |
| GSE23400 | LSM6 | 11157 | 205036_at | 0.3447 | 0.0000 | |
| GSE26886 | LSM6 | 11157 | 205036_at | 0.2343 | 0.2637 | |
| GSE29001 | LSM6 | 11157 | 205036_at | 0.4866 | 0.1260 | |
| GSE38129 | LSM6 | 11157 | 205036_at | 0.4785 | 0.0001 | |
| GSE45670 | LSM6 | 11157 | 205036_at | 0.2905 | 0.0445 | |
| GSE53622 | LSM6 | 11157 | 105413 | 0.2599 | 0.0015 | |
| GSE53624 | LSM6 | 11157 | 105413 | 0.5517 | 0.0000 | |
| GSE63941 | LSM6 | 11157 | 205036_at | 0.6179 | 0.0696 | |
| GSE77861 | LSM6 | 11157 | 205036_at | 0.1090 | 0.6314 | |
| GSE97050 | LSM6 | 11157 | A_23_P259451 | 0.3589 | 0.3441 | |
| SRP007169 | LSM6 | 11157 | RNAseq | 0.0949 | 0.8090 | |
| SRP008496 | LSM6 | 11157 | RNAseq | 0.2039 | 0.5192 | |
| SRP064894 | LSM6 | 11157 | RNAseq | 0.2645 | 0.2462 | |
| SRP133303 | LSM6 | 11157 | RNAseq | 0.6066 | 0.0058 | |
| SRP159526 | LSM6 | 11157 | RNAseq | 0.4686 | 0.1040 | |
| SRP193095 | LSM6 | 11157 | RNAseq | 0.0652 | 0.6092 | |
| SRP219564 | LSM6 | 11157 | RNAseq | 0.4086 | 0.2839 | |
| TCGA | LSM6 | 11157 | RNAseq | 0.3071 | 0.0001 |
Upregulated datasets: 0; Downregulated datasets: 0.
Survival by LSM6 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of LSM6:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | LSM6 | 11157 | 0 | 12 | 18 | |
| GSE20123 | LSM6 | 11157 | 0 | 12 | 18 | |
| GSE43470 | LSM6 | 11157 | 0 | 13 | 30 | |
| GSE46452 | LSM6 | 11157 | 1 | 36 | 22 | |
| GSE47630 | LSM6 | 11157 | 0 | 22 | 18 | |
| GSE54993 | LSM6 | 11157 | 10 | 0 | 60 | |
| GSE54994 | LSM6 | 11157 | 2 | 11 | 40 | |
| GSE60625 | LSM6 | 11157 | 0 | 1 | 10 | |
| GSE74703 | LSM6 | 11157 | 0 | 11 | 25 | |
| GSE74704 | LSM6 | 11157 | 0 | 7 | 13 | |
| TCGA | LSM6 | 11157 | 12 | 32 | 52 |
Total number of gains: 25; Total number of losses: 157; Total Number of normals: 306.
Somatic mutations of LSM6:
Generating mutation plots.
Highly correlated genes for LSM6:
Showing top 20/1110 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| LSM6 | CPT1C | 0.779624 | 3 | 0 | 3 |
| LSM6 | SMCR8 | 0.751212 | 3 | 0 | 3 |
| LSM6 | SRPK1 | 0.743776 | 3 | 0 | 3 |
| LSM6 | INTS10 | 0.724893 | 4 | 0 | 3 |
| LSM6 | SLC7A6OS | 0.72249 | 3 | 0 | 3 |
| LSM6 | PHF6 | 0.702274 | 3 | 0 | 3 |
| LSM6 | RPS16 | 0.691134 | 3 | 0 | 3 |
| LSM6 | CENPBD1 | 0.687248 | 4 | 0 | 3 |
| LSM6 | FAM167B | 0.68699 | 3 | 0 | 3 |
| LSM6 | RNASET2 | 0.686108 | 4 | 0 | 4 |
| LSM6 | SORD | 0.686008 | 3 | 0 | 3 |
| LSM6 | MAD2L1 | 0.681752 | 11 | 0 | 10 |
| LSM6 | OAF | 0.680008 | 3 | 0 | 3 |
| LSM6 | PREX1 | 0.669245 | 3 | 0 | 3 |
| LSM6 | ILF2 | 0.668059 | 11 | 0 | 9 |
| LSM6 | VAC14 | 0.666811 | 5 | 0 | 4 |
| LSM6 | MITD1 | 0.663063 | 4 | 0 | 4 |
| LSM6 | SLC25A19 | 0.662451 | 4 | 0 | 4 |
| LSM6 | SAAL1 | 0.662269 | 5 | 0 | 4 |
| LSM6 | FMNL3 | 0.662135 | 5 | 0 | 4 |
For details and further investigation, click here
