ILF2

 

Full name: interleukin enhancer binding factor 2 Alias Symbol: NF45
Type: protein-coding gene Cytoband: 1q21.3
Entrez ID: 3608 HGNC ID: HGNC:6037 Ensembl Gene: ENSG00000143621 OMIM ID: 603181
Drug and gene relationship at DGIdb
Screen Evidence:

 

Expression of ILF2:

 

Dataset Gene EntrezID Probe Log2FC Adj.pValue Expression
GSE17351 ILF2 3608 200052_s_at 0.8765 0.0200
GSE20347 ILF2 3608 200052_s_at 0.9604 0.0001
GSE23400 ILF2 3608 200052_s_at 1.0420 0.0000
GSE26886 ILF2 3608 200052_s_at -0.4020 0.2328
GSE29001 ILF2 3608 200052_s_at 0.8183 0.1462
GSE38129 ILF2 3608 200052_s_at 1.2846 0.0000
GSE45670 ILF2 3608 200052_s_at 0.4100 0.0427
GSE53622 ILF2 3608 46863 0.9473 0.0000
GSE53624 ILF2 3608 46863 1.0511 0.0000
GSE63941 ILF2 3608 200052_s_at 1.1282 0.0019
GSE77861 ILF2 3608 200052_s_at 0.9618 0.0122
GSE97050 ILF2 3608 A_23_P257956 0.7154 0.1186
SRP007169 ILF2 3608 RNAseq 0.0421 0.8950
SRP008496 ILF2 3608 RNAseq 0.1940 0.3621
SRP064894 ILF2 3608 RNAseq 0.3894 0.0210
SRP133303 ILF2 3608 RNAseq 0.7411 0.0000
SRP159526 ILF2 3608 RNAseq 1.0786 0.0000
SRP193095 ILF2 3608 RNAseq 0.3859 0.0022
SRP219564 ILF2 3608 RNAseq 0.5367 0.1604
TCGA ILF2 3608 RNAseq 0.2596 0.0000

Upregulated datasets: 5; Downregulated datasets: 0.  

 

Survival by ILF2 expression:

 

GSE53622GSE53624TCGA

 

Note: Click image to view full size file.  

Copy number change of ILF2:

 

Dataset Gene EntrezID Gain Loss Normal Detail
GSE15526 ILF2 3608 14 0 16
GSE20123 ILF2 3608 14 0 16
GSE43470 ILF2 3608 7 2 34
GSE46452 ILF2 3608 2 1 56
GSE47630 ILF2 3608 14 0 26
GSE54993 ILF2 3608 0 4 66
GSE54994 ILF2 3608 16 0 37
GSE60625 ILF2 3608 0 0 11
GSE74703 ILF2 3608 6 1 29
GSE74704 ILF2 3608 7 0 13
TCGA ILF2 3608 38 2 56

Total number of gains: 118; Total number of losses: 10; Total Number of normals: 360.  

 

Somatic mutations of ILF2:

 

Generating mutation plots.

 

Highly correlated genes for ILF2:

 

Showing top 20/1659 corelated genes with mean PCC>0.5.
Gene1 Gene2 Mean PCC Num. Datasets Num. PCC<0 Num. PCC>0.5
ILF2DCAF130.832686606
ILF2CCT40.81792111011
ILF2CKS1B0.80411812012
ILF2EFTUD20.795646707
ILF2RANBP10.78815410010
ILF2SSR20.783712012
ILF2NDUFS30.779768303
ILF2SETX0.778797303
ILF2FAM89A0.778117303
ILF2TPX20.77759312012
ILF2RUVBL10.77279512012
ILF2UCK20.770811404
ILF2STARD70.76879411011
ILF2SSRP10.76197611011
ILF2MMS22L0.761351303
ILF2SNRPB0.76006511011
ILF2SIX40.759749606
ILF2UBE2T0.758399808
ILF2NOP560.757052303
ILF2TUBB0.75626812011

For details and further investigation, click here