| Full name: lymphocyte antigen 6 family member K | Alias Symbol: HSJ001348|FLJ35226|CT97 | ||
| Type: protein-coding gene | Cytoband: 8q24.3 | ||
| Entrez ID: 54742 | HGNC ID: HGNC:24225 | Ensembl Gene: ENSG00000160886 | OMIM ID: 615093 |
| Drug and gene relationship at DGIdb | |||
Expression of LY6K:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | LY6K | 54742 | 223687_s_at | 1.2180 | 0.4370 | |
| GSE26886 | LY6K | 54742 | 223687_s_at | 0.5485 | 0.4280 | |
| GSE45670 | LY6K | 54742 | 223687_s_at | 0.7667 | 0.0114 | |
| GSE63941 | LY6K | 54742 | 223687_s_at | 2.5060 | 0.1562 | |
| GSE77861 | LY6K | 54742 | 223687_s_at | 0.2584 | 0.6790 | |
| GSE97050 | LY6K | 54742 | A_23_P397293 | 1.1414 | 0.1424 | |
| SRP007169 | LY6K | 54742 | RNAseq | -0.9293 | 0.1130 | |
| SRP008496 | LY6K | 54742 | RNAseq | -0.9376 | 0.0140 | |
| SRP064894 | LY6K | 54742 | RNAseq | 1.1135 | 0.0398 | |
| SRP133303 | LY6K | 54742 | RNAseq | 0.4742 | 0.1174 | |
| SRP159526 | LY6K | 54742 | RNAseq | -0.5265 | 0.4548 | |
| SRP219564 | LY6K | 54742 | RNAseq | 1.5187 | 0.1100 | |
| TCGA | LY6K | 54742 | RNAseq | 1.2541 | 0.0000 |
Upregulated datasets: 2; Downregulated datasets: 0.
Survival by LY6K expression:
 |
| TCGA |
Note: Click image to view full size file.
Copy number change of LY6K:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | LY6K | 54742 | 16 | 1 | 13 | |
| GSE20123 | LY6K | 54742 | 17 | 1 | 12 | |
| GSE43470 | LY6K | 54742 | 17 | 2 | 24 | |
| GSE46452 | LY6K | 54742 | 27 | 0 | 32 | |
| GSE47630 | LY6K | 54742 | 23 | 1 | 16 | |
| GSE54993 | LY6K | 54742 | 0 | 25 | 45 | |
| GSE54994 | LY6K | 54742 | 39 | 1 | 13 | |
| GSE60625 | LY6K | 54742 | 3 | 4 | 4 | |
| GSE74703 | LY6K | 54742 | 15 | 1 | 20 | |
| GSE74704 | LY6K | 54742 | 10 | 0 | 10 | |
| TCGA | LY6K | 54742 | 63 | 2 | 31 |
Total number of gains: 230; Total number of losses: 38; Total Number of normals: 220.
Somatic mutations of LY6K:
Generating mutation plots.
Highly correlated genes for LY6K:
Showing top 20/134 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| LY6K | NOP14 | 0.772669 | 3 | 0 | 3 |
| LY6K | STMN1 | 0.729299 | 3 | 0 | 3 |
| LY6K | ANKRD36 | 0.718181 | 3 | 0 | 3 |
| LY6K | B4GALT7 | 0.716795 | 3 | 0 | 3 |
| LY6K | GTPBP4 | 0.714511 | 3 | 0 | 3 |
| LY6K | PPP1R14B | 0.712624 | 3 | 0 | 3 |
| LY6K | BRMS1 | 0.697752 | 3 | 0 | 3 |
| LY6K | CCNE2 | 0.697668 | 3 | 0 | 3 |
| LY6K | PPP1R13L | 0.696256 | 3 | 0 | 3 |
| LY6K | LMNB1 | 0.673648 | 3 | 0 | 3 |
| LY6K | TOP1 | 0.669756 | 4 | 0 | 3 |
| LY6K | CNKSR1 | 0.665313 | 3 | 0 | 3 |
| LY6K | MYO1B | 0.659674 | 3 | 0 | 3 |
| LY6K | PNP | 0.657485 | 3 | 0 | 3 |
| LY6K | RFC3 | 0.654581 | 3 | 0 | 3 |
| LY6K | ARL10 | 0.654376 | 3 | 0 | 3 |
| LY6K | PPARD | 0.653254 | 4 | 0 | 4 |
| LY6K | CDCA7 | 0.652603 | 3 | 0 | 3 |
| LY6K | IL32 | 0.651839 | 3 | 0 | 3 |
| LY6K | LYAR | 0.650113 | 4 | 0 | 4 |
For details and further investigation, click here
