STMN1

 

Full name: stathmin 1 Alias Symbol: SMN|OP18|PR22|PP19|PP17|Lag|FLJ32206
Type: protein-coding gene Cytoband: 1p36.11
Entrez ID: 3925 HGNC ID: HGNC:6510 Ensembl Gene: ENSG00000117632 OMIM ID: 151442
Drug and gene relationship at DGIdb

 

STMN1 involved pathways:

KEGG pathway Description View
hsa04010MAPK signaling pathway

 

Expression of STMN1:

 

Dataset Gene EntrezID Probe Log2FC Adj.pValue Expression
GSE17351 STMN1 3925 200783_s_at 0.9183 0.0201
GSE20347 STMN1 3925 200783_s_at 1.1136 0.0000
GSE23400 STMN1 3925 200783_s_at 0.8358 0.0000
GSE26886 STMN1 3925 200783_s_at 0.3925 0.0205
GSE29001 STMN1 3925 200783_s_at 1.1812 0.0004
GSE38129 STMN1 3925 200783_s_at 1.2986 0.0000
GSE45670 STMN1 3925 200783_s_at 0.7573 0.0031
GSE53622 STMN1 3925 3955 1.2124 0.0000
GSE53624 STMN1 3925 3955 1.4874 0.0000
GSE63941 STMN1 3925 200783_s_at 1.1501 0.0770
GSE77861 STMN1 3925 200783_s_at 0.4563 0.1023
GSE97050 STMN1 3925 A_33_P3317523 1.3312 0.0607
SRP007169 STMN1 3925 RNAseq 1.4750 0.0001
SRP008496 STMN1 3925 RNAseq 1.3039 0.0000
SRP064894 STMN1 3925 RNAseq 1.8982 0.0000
SRP133303 STMN1 3925 RNAseq 1.2199 0.0000
SRP159526 STMN1 3925 RNAseq 1.6887 0.0029
SRP193095 STMN1 3925 RNAseq 0.7062 0.0000
SRP219564 STMN1 3925 RNAseq 1.0279 0.0193
TCGA STMN1 3925 RNAseq 0.6568 0.0000

Upregulated datasets: 11; Downregulated datasets: 0.  

 

Survival by STMN1 expression:

 

GSE53622GSE53624TCGA

 

Note: Click image to view full size file.  

Copy number change of STMN1:

 

Dataset Gene EntrezID Gain Loss Normal Detail
GSE15526 STMN1 3925 0 5 25
GSE20123 STMN1 3925 0 4 26
GSE43470 STMN1 3925 2 6 35
GSE46452 STMN1 3925 5 1 53
GSE47630 STMN1 3925 8 3 29
GSE54993 STMN1 3925 2 1 67
GSE54994 STMN1 3925 10 4 39
GSE60625 STMN1 3925 0 0 11
GSE74703 STMN1 3925 1 4 31
GSE74704 STMN1 3925 0 0 20
TCGA STMN1 3925 9 24 63

Total number of gains: 37; Total number of losses: 52; Total Number of normals: 399.  

 

Somatic mutations of STMN1:

 

Generating mutation plots.

 

Highly correlated genes for STMN1:

 

Showing top 20/1770 corelated genes with mean PCC>0.5.
Gene1 Gene2 Mean PCC Num. Datasets Num. PCC<0 Num. PCC>0.5
STMN1CENPF0.81077613012
STMN1TOP2A0.79799813013
STMN1NEK20.78560213013
STMN1KIF2C0.77941712012
STMN1UCK20.776247303
STMN1CDCA20.769754606
STMN1CBX30.76727110010
STMN1TIMELESS0.76658413013
STMN1DTL0.76484113012
STMN1UBE2C0.76395913012
STMN1CDK10.76183312012
STMN1MMS22L0.758698303
STMN1MCM20.75859512012
STMN1BUB10.75804511010
STMN1DNMT10.75743913012
STMN1GINS10.75564212012
STMN1ASPM0.75532513012
STMN1PRC10.74967813012
STMN1ATAD20.74817112012
STMN1SMCR80.747748303

For details and further investigation, click here