| Full name: protein phosphatase 1 regulatory subunit 13 like | Alias Symbol: RAI|IASPP | ||
| Type: protein-coding gene | Cytoband: 19q13.32 | ||
| Entrez ID: 10848 | HGNC ID: HGNC:18838 | Ensembl Gene: ENSG00000104881 | OMIM ID: 607463 |
| Drug and gene relationship at DGIdb | |||
Expression of PPP1R13L:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | PPP1R13L | 10848 | 218849_s_at | -0.8717 | 0.2981 | |
| GSE20347 | PPP1R13L | 10848 | 218849_s_at | -1.1817 | 0.0000 | |
| GSE23400 | PPP1R13L | 10848 | 218849_s_at | -0.5030 | 0.0000 | |
| GSE26886 | PPP1R13L | 10848 | 218849_s_at | -0.3369 | 0.2445 | |
| GSE29001 | PPP1R13L | 10848 | 218849_s_at | -0.9762 | 0.0027 | |
| GSE38129 | PPP1R13L | 10848 | 218849_s_at | -0.4434 | 0.2399 | |
| GSE45670 | PPP1R13L | 10848 | 218849_s_at | -0.3781 | 0.2008 | |
| GSE53622 | PPP1R13L | 10848 | 160637 | -0.5659 | 0.0004 | |
| GSE53624 | PPP1R13L | 10848 | 160637 | -0.9339 | 0.0000 | |
| GSE63941 | PPP1R13L | 10848 | 218849_s_at | 2.5167 | 0.0000 | |
| GSE77861 | PPP1R13L | 10848 | 218849_s_at | -0.7666 | 0.0578 | |
| GSE97050 | PPP1R13L | 10848 | A_23_P119095 | 0.5070 | 0.3375 | |
| SRP007169 | PPP1R13L | 10848 | RNAseq | -2.2175 | 0.0000 | |
| SRP008496 | PPP1R13L | 10848 | RNAseq | -2.5547 | 0.0000 | |
| SRP064894 | PPP1R13L | 10848 | RNAseq | -0.7202 | 0.0380 | |
| SRP133303 | PPP1R13L | 10848 | RNAseq | -0.8743 | 0.0012 | |
| SRP159526 | PPP1R13L | 10848 | RNAseq | -1.5399 | 0.0000 | |
| SRP193095 | PPP1R13L | 10848 | RNAseq | -0.8965 | 0.0031 | |
| SRP219564 | PPP1R13L | 10848 | RNAseq | -1.0324 | 0.2047 | |
| TCGA | PPP1R13L | 10848 | RNAseq | 0.4694 | 0.0000 |
Upregulated datasets: 1; Downregulated datasets: 4.
Survival by PPP1R13L expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of PPP1R13L:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | PPP1R13L | 10848 | 4 | 5 | 21 | |
| GSE20123 | PPP1R13L | 10848 | 4 | 4 | 22 | |
| GSE43470 | PPP1R13L | 10848 | 3 | 11 | 29 | |
| GSE46452 | PPP1R13L | 10848 | 45 | 1 | 13 | |
| GSE47630 | PPP1R13L | 10848 | 8 | 6 | 26 | |
| GSE54993 | PPP1R13L | 10848 | 17 | 4 | 49 | |
| GSE54994 | PPP1R13L | 10848 | 6 | 12 | 35 | |
| GSE60625 | PPP1R13L | 10848 | 9 | 0 | 2 | |
| GSE74703 | PPP1R13L | 10848 | 3 | 7 | 26 | |
| GSE74704 | PPP1R13L | 10848 | 4 | 2 | 14 | |
| TCGA | PPP1R13L | 10848 | 15 | 16 | 65 |
Total number of gains: 118; Total number of losses: 68; Total Number of normals: 302.
Somatic mutations of PPP1R13L:
Generating mutation plots.
Highly correlated genes for PPP1R13L:
Showing top 20/1147 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| PPP1R13L | NIPAL1 | 0.818371 | 3 | 0 | 3 |
| PPP1R13L | ELOVL1 | 0.800776 | 3 | 0 | 3 |
| PPP1R13L | SLC25A39 | 0.794911 | 3 | 0 | 3 |
| PPP1R13L | ARAP2 | 0.756227 | 3 | 0 | 3 |
| PPP1R13L | C19orf33 | 0.753546 | 9 | 0 | 9 |
| PPP1R13L | DGKA | 0.751006 | 12 | 0 | 11 |
| PPP1R13L | LPAR5 | 0.749956 | 5 | 0 | 5 |
| PPP1R13L | ZDHHC5 | 0.748959 | 4 | 0 | 4 |
| PPP1R13L | RAB25 | 0.740084 | 11 | 0 | 11 |
| PPP1R13L | SH3GL1 | 0.736167 | 11 | 0 | 11 |
| PPP1R13L | PKP3 | 0.735833 | 12 | 0 | 11 |
| PPP1R13L | GNA15 | 0.735592 | 13 | 0 | 13 |
| PPP1R13L | DUOX1 | 0.734119 | 12 | 0 | 12 |
| PPP1R13L | CKMT1A | 0.729466 | 3 | 0 | 3 |
| PPP1R13L | RGS14 | 0.727743 | 10 | 0 | 9 |
| PPP1R13L | EPGN | 0.724164 | 3 | 0 | 3 |
| PPP1R13L | CNKSR1 | 0.723717 | 12 | 0 | 12 |
| PPP1R13L | LTA4H | 0.720198 | 3 | 0 | 3 |
| PPP1R13L | S100A11 | 0.719145 | 12 | 0 | 11 |
| PPP1R13L | VAV3 | 0.717061 | 10 | 0 | 10 |
For details and further investigation, click here
