MYO1B

 

Full name: myosin IB Alias Symbol: myr1
Type: protein-coding gene Cytoband: 2q32.3
Entrez ID: 4430 HGNC ID: HGNC:7596 Ensembl Gene: ENSG00000128641 OMIM ID: 606537
Drug and gene relationship at DGIdb

 

Expression of MYO1B:

 

Dataset Gene EntrezID Probe Log2FC Adj.pValue Expression
GSE17351 MYO1B 4430 212365_at 1.4320 0.1378
GSE20347 MYO1B 4430 212364_at 1.4121 0.0002
GSE23400 MYO1B 4430 212365_at 0.9961 0.0000
GSE26886 MYO1B 4430 212364_at 1.1393 0.0017
GSE29001 MYO1B 4430 212364_at 1.1453 0.0007
GSE38129 MYO1B 4430 212364_at 1.6302 0.0000
GSE45670 MYO1B 4430 212365_at 2.1248 0.0000
GSE53622 MYO1B 4430 49636 1.8572 0.0000
GSE53624 MYO1B 4430 74779 1.7440 0.0000
GSE63941 MYO1B 4430 212365_at -0.3572 0.6542
GSE77861 MYO1B 4430 212364_at 1.4865 0.0040
GSE97050 MYO1B 4430 A_24_P7143 1.7245 0.1163
SRP007169 MYO1B 4430 RNAseq 0.8195 0.0716
SRP008496 MYO1B 4430 RNAseq 0.2517 0.5130
SRP064894 MYO1B 4430 RNAseq 1.5451 0.0000
SRP133303 MYO1B 4430 RNAseq 2.2450 0.0000
SRP159526 MYO1B 4430 RNAseq 0.9697 0.0000
SRP193095 MYO1B 4430 RNAseq 1.7833 0.0000
SRP219564 MYO1B 4430 RNAseq 0.9973 0.0641
TCGA MYO1B 4430 RNAseq 0.4906 0.0000

Upregulated datasets: 11; Downregulated datasets: 0.  

 

Survival by MYO1B expression:

 

GSE53622GSE53624TCGA

 

Note: Click image to view full size file.  

Copy number change of MYO1B:

 

Dataset Gene EntrezID Gain Loss Normal Detail
GSE15526 MYO1B 4430 8 2 20
GSE20123 MYO1B 4430 8 2 20
GSE43470 MYO1B 4430 3 1 39
GSE46452 MYO1B 4430 1 4 54
GSE47630 MYO1B 4430 4 5 31
GSE54993 MYO1B 4430 0 5 65
GSE54994 MYO1B 4430 12 6 35
GSE60625 MYO1B 4430 0 3 8
GSE74703 MYO1B 4430 2 1 33
GSE74704 MYO1B 4430 3 2 15
TCGA MYO1B 4430 25 7 64

Total number of gains: 66; Total number of losses: 38; Total Number of normals: 384.  

 

Somatic mutations of MYO1B:

 

Generating mutation plots.

 

Highly correlated genes for MYO1B:

 

Showing top 20/1629 corelated genes with mean PCC>0.5.
Gene1 Gene2 Mean PCC Num. Datasets Num. PCC<0 Num. PCC>0.5
MYO1BCDH30.7985810010
MYO1BDCBLD10.76777807
MYO1BWDR660.763153707
MYO1BITGA60.74860112012
MYO1BLAMC20.74359312012
MYO1BEME10.74032505
MYO1BFSCN10.72764412010
MYO1BUHRF10.727487707
MYO1BSPRR2G0.725437403
MYO1BXPR10.722853706
MYO1BIGF2BP20.72250710010
MYO1BKIF140.71830911010
MYO1BPLAU0.71457413012
MYO1BTMC80.7144404
MYO1BFAM91A10.709447606
MYO1BANLN0.708384707
MYO1BMSANTD30.707731606
MYO1BVCAM10.707192303
MYO1BCTHRC10.705062706
MYO1BMPLKIP0.702522606

For details and further investigation, click here