| Full name: high mobility group nucleosomal binding domain 3 | Alias Symbol: | ||
| Type: protein-coding gene | Cytoband: 6q14.1 | ||
| Entrez ID: 9324 | HGNC ID: HGNC:12312 | Ensembl Gene: ENSG00000118418 | OMIM ID: 604502 |
| Drug and gene relationship at DGIdb | |||
Expression of HMGN3:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | HMGN3 | 9324 | 209377_s_at | -0.1682 | 0.7164 | |
| GSE20347 | HMGN3 | 9324 | 209377_s_at | -0.0066 | 0.9830 | |
| GSE23400 | HMGN3 | 9324 | 209377_s_at | 0.0104 | 0.9040 | |
| GSE26886 | HMGN3 | 9324 | 209377_s_at | 0.2379 | 0.2231 | |
| GSE29001 | HMGN3 | 9324 | 209377_s_at | -0.2052 | 0.3395 | |
| GSE38129 | HMGN3 | 9324 | 209377_s_at | 0.0144 | 0.9410 | |
| GSE45670 | HMGN3 | 9324 | 209377_s_at | -0.0255 | 0.9067 | |
| GSE53622 | HMGN3 | 9324 | 37938 | -0.0492 | 0.5692 | |
| GSE53624 | HMGN3 | 9324 | 37938 | 0.0426 | 0.5365 | |
| GSE63941 | HMGN3 | 9324 | 209377_s_at | 0.6958 | 0.1383 | |
| GSE77861 | HMGN3 | 9324 | 209377_s_at | -0.2402 | 0.5030 | |
| GSE97050 | HMGN3 | 9324 | A_24_P132099 | -0.1365 | 0.5415 | |
| SRP007169 | HMGN3 | 9324 | RNAseq | 0.0911 | 0.8615 | |
| SRP008496 | HMGN3 | 9324 | RNAseq | 0.0690 | 0.8362 | |
| SRP064894 | HMGN3 | 9324 | RNAseq | -0.2962 | 0.0844 | |
| SRP133303 | HMGN3 | 9324 | RNAseq | -0.3582 | 0.0231 | |
| SRP159526 | HMGN3 | 9324 | RNAseq | -0.0446 | 0.8804 | |
| SRP193095 | HMGN3 | 9324 | RNAseq | -0.4444 | 0.0062 | |
| SRP219564 | HMGN3 | 9324 | RNAseq | -0.4338 | 0.2197 | |
| TCGA | HMGN3 | 9324 | RNAseq | -0.0466 | 0.4770 |
Upregulated datasets: 0; Downregulated datasets: 0.
Survival by HMGN3 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of HMGN3:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | HMGN3 | 9324 | 2 | 4 | 24 | |
| GSE20123 | HMGN3 | 9324 | 2 | 3 | 25 | |
| GSE43470 | HMGN3 | 9324 | 2 | 1 | 40 | |
| GSE46452 | HMGN3 | 9324 | 3 | 11 | 45 | |
| GSE47630 | HMGN3 | 9324 | 8 | 6 | 26 | |
| GSE54993 | HMGN3 | 9324 | 3 | 2 | 65 | |
| GSE54994 | HMGN3 | 9324 | 8 | 7 | 38 | |
| GSE60625 | HMGN3 | 9324 | 0 | 1 | 10 | |
| GSE74703 | HMGN3 | 9324 | 2 | 1 | 33 | |
| GSE74704 | HMGN3 | 9324 | 1 | 2 | 17 | |
| TCGA | HMGN3 | 9324 | 6 | 22 | 68 |
Total number of gains: 37; Total number of losses: 60; Total Number of normals: 391.
Somatic mutations of HMGN3:
Generating mutation plots.
Highly correlated genes for HMGN3:
Showing top 20/83 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| HMGN3 | LYPLAL1 | 0.816878 | 3 | 0 | 3 |
| HMGN3 | ZNF655 | 0.763572 | 3 | 0 | 3 |
| HMGN3 | SDR39U1 | 0.759228 | 3 | 0 | 3 |
| HMGN3 | TBCA | 0.734166 | 3 | 0 | 3 |
| HMGN3 | VAPA | 0.724442 | 3 | 0 | 3 |
| HMGN3 | FGFR3 | 0.717109 | 3 | 0 | 3 |
| HMGN3 | PROS1 | 0.714508 | 3 | 0 | 3 |
| HMGN3 | TRPC1 | 0.712533 | 3 | 0 | 3 |
| HMGN3 | JDP2 | 0.708281 | 3 | 0 | 3 |
| HMGN3 | HEATR5B | 0.708229 | 3 | 0 | 3 |
| HMGN3 | FOXO3 | 0.706227 | 3 | 0 | 3 |
| HMGN3 | CLN8 | 0.69786 | 4 | 0 | 3 |
| HMGN3 | MEGF6 | 0.692872 | 4 | 0 | 3 |
| HMGN3 | COX6B1 | 0.680139 | 3 | 0 | 3 |
| HMGN3 | ECHDC1 | 0.679646 | 3 | 0 | 3 |
| HMGN3 | CD164 | 0.678499 | 4 | 0 | 3 |
| HMGN3 | PLS1 | 0.677926 | 3 | 0 | 3 |
| HMGN3 | OCIAD1 | 0.67518 | 4 | 0 | 3 |
| HMGN3 | ASS1 | 0.672561 | 4 | 0 | 3 |
| HMGN3 | DLL1 | 0.671667 | 3 | 0 | 3 |
For details and further investigation, click here
