| Full name: NAD kinase | Alias Symbol: FLJ13052 | ||
| Type: protein-coding gene | Cytoband: 1p36.33 | ||
| Entrez ID: 65220 | HGNC ID: HGNC:29831 | Ensembl Gene: ENSG00000008130 | OMIM ID: 611616 |
| Drug and gene relationship at DGIdb | |||
Screen Evidence:
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Expression of NADK:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | NADK | 65220 | 208918_s_at | 0.7748 | 0.1458 | |
| GSE20347 | NADK | 65220 | 208918_s_at | 0.5531 | 0.0062 | |
| GSE23400 | NADK | 65220 | 208919_s_at | 0.3471 | 0.0000 | |
| GSE26886 | NADK | 65220 | 208918_s_at | 1.4136 | 0.0000 | |
| GSE29001 | NADK | 65220 | 208918_s_at | 0.6182 | 0.0315 | |
| GSE38129 | NADK | 65220 | 208918_s_at | 0.6468 | 0.0002 | |
| GSE45670 | NADK | 65220 | 208918_s_at | 0.7881 | 0.0000 | |
| GSE53622 | NADK | 65220 | 713 | 0.1503 | 0.0451 | |
| GSE53624 | NADK | 65220 | 713 | 0.1414 | 0.0141 | |
| GSE63941 | NADK | 65220 | 208918_s_at | 0.8985 | 0.0671 | |
| GSE77861 | NADK | 65220 | 208918_s_at | 0.0761 | 0.7661 | |
| GSE97050 | NADK | 65220 | A_23_P200056 | 0.0630 | 0.8269 | |
| SRP007169 | NADK | 65220 | RNAseq | 0.5037 | 0.3560 | |
| SRP008496 | NADK | 65220 | RNAseq | 0.2288 | 0.5101 | |
| SRP064894 | NADK | 65220 | RNAseq | 0.7334 | 0.0000 | |
| SRP133303 | NADK | 65220 | RNAseq | 0.4222 | 0.0061 | |
| SRP159526 | NADK | 65220 | RNAseq | 0.4110 | 0.0319 | |
| SRP193095 | NADK | 65220 | RNAseq | 0.1384 | 0.4433 | |
| SRP219564 | NADK | 65220 | RNAseq | 0.2727 | 0.4238 | |
| TCGA | NADK | 65220 | RNAseq | -0.1482 | 0.0012 |
Upregulated datasets: 1; Downregulated datasets: 0.
Survival by NADK expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of NADK:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | NADK | 65220 | 3 | 7 | 20 | |
| GSE20123 | NADK | 65220 | 3 | 6 | 21 | |
| GSE43470 | NADK | 65220 | 3 | 5 | 35 | |
| GSE46452 | NADK | 65220 | 7 | 1 | 51 | |
| GSE47630 | NADK | 65220 | 8 | 4 | 28 | |
| GSE54993 | NADK | 65220 | 2 | 2 | 66 | |
| GSE54994 | NADK | 65220 | 15 | 2 | 36 | |
| GSE60625 | NADK | 65220 | 0 | 0 | 11 | |
| GSE74703 | NADK | 65220 | 3 | 3 | 30 | |
| GSE74704 | NADK | 65220 | 3 | 0 | 17 | |
| TCGA | NADK | 65220 | 14 | 20 | 62 |
Total number of gains: 61; Total number of losses: 50; Total Number of normals: 377.
Somatic mutations of NADK:
Generating mutation plots.
Highly correlated genes for NADK:
Showing top 20/899 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| NADK | SSBP4 | 0.811004 | 3 | 0 | 3 |
| NADK | WDR81 | 0.783341 | 3 | 0 | 3 |
| NADK | CACNA1B | 0.776343 | 3 | 0 | 3 |
| NADK | ACBD6 | 0.772089 | 3 | 0 | 3 |
| NADK | RICTOR | 0.758982 | 3 | 0 | 3 |
| NADK | LEMD2 | 0.737728 | 3 | 0 | 3 |
| NADK | DHX37 | 0.734721 | 5 | 0 | 5 |
| NADK | MICA | 0.73412 | 3 | 0 | 3 |
| NADK | NTPCR | 0.728503 | 3 | 0 | 3 |
| NADK | TMEM63B | 0.725966 | 3 | 0 | 3 |
| NADK | FLVCR1 | 0.724512 | 3 | 0 | 3 |
| NADK | NCOA6 | 0.721568 | 4 | 0 | 3 |
| NADK | LYRM4 | 0.720313 | 4 | 0 | 3 |
| NADK | ANAPC10 | 0.717972 | 4 | 0 | 4 |
| NADK | LINC01128 | 0.716408 | 4 | 0 | 4 |
| NADK | TGIF2 | 0.715057 | 3 | 0 | 3 |
| NADK | PEX14 | 0.715052 | 3 | 0 | 3 |
| NADK | RIOK1 | 0.714302 | 4 | 0 | 3 |
| NADK | SFMBT1 | 0.713363 | 3 | 0 | 3 |
| NADK | ROMO1 | 0.710927 | 3 | 0 | 3 |
For details and further investigation, click here
