| Full name: MAF bZIP transcription factor F | Alias Symbol: hMafF | ||
| Type: protein-coding gene | Cytoband: 22q13.1 | ||
| Entrez ID: 23764 | HGNC ID: HGNC:6780 | Ensembl Gene: ENSG00000185022 | OMIM ID: 604877 |
| Drug and gene relationship at DGIdb | |||
Expression of MAFF:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | MAFF | 23764 | 36711_at | -1.2650 | 0.0979 | |
| GSE20347 | MAFF | 23764 | 36711_at | -1.2939 | 0.0000 | |
| GSE23400 | MAFF | 23764 | 36711_at | -1.5422 | 0.0000 | |
| GSE26886 | MAFF | 23764 | 36711_at | -1.6763 | 0.0001 | |
| GSE29001 | MAFF | 23764 | 36711_at | -1.1035 | 0.0126 | |
| GSE38129 | MAFF | 23764 | 36711_at | -1.2584 | 0.0000 | |
| GSE45670 | MAFF | 23764 | 36711_at | -0.8131 | 0.0216 | |
| GSE53622 | MAFF | 23764 | 67041 | -0.6528 | 0.0000 | |
| GSE53624 | MAFF | 23764 | 67041 | -0.8957 | 0.0000 | |
| GSE63941 | MAFF | 23764 | 36711_at | -0.6637 | 0.5514 | |
| GSE77861 | MAFF | 23764 | 36711_at | -0.9035 | 0.0341 | |
| GSE97050 | MAFF | 23764 | A_23_P103110 | -0.5609 | 0.1581 | |
| SRP007169 | MAFF | 23764 | RNAseq | -2.7434 | 0.0000 | |
| SRP008496 | MAFF | 23764 | RNAseq | -2.9228 | 0.0000 | |
| SRP064894 | MAFF | 23764 | RNAseq | -1.5628 | 0.0000 | |
| SRP133303 | MAFF | 23764 | RNAseq | -1.1230 | 0.0000 | |
| SRP159526 | MAFF | 23764 | RNAseq | -1.4230 | 0.0026 | |
| SRP193095 | MAFF | 23764 | RNAseq | -1.3171 | 0.0000 | |
| SRP219564 | MAFF | 23764 | RNAseq | -1.3223 | 0.0009 | |
| TCGA | MAFF | 23764 | RNAseq | -0.2525 | 0.0033 |
Upregulated datasets: 0; Downregulated datasets: 12.
Survival by MAFF expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of MAFF:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | MAFF | 23764 | 6 | 5 | 19 | |
| GSE20123 | MAFF | 23764 | 6 | 4 | 20 | |
| GSE43470 | MAFF | 23764 | 5 | 5 | 33 | |
| GSE46452 | MAFF | 23764 | 32 | 2 | 25 | |
| GSE47630 | MAFF | 23764 | 9 | 4 | 27 | |
| GSE54993 | MAFF | 23764 | 3 | 6 | 61 | |
| GSE54994 | MAFF | 23764 | 9 | 7 | 37 | |
| GSE60625 | MAFF | 23764 | 5 | 0 | 6 | |
| GSE74703 | MAFF | 23764 | 5 | 4 | 27 | |
| GSE74704 | MAFF | 23764 | 3 | 2 | 15 | |
| TCGA | MAFF | 23764 | 27 | 15 | 54 |
Total number of gains: 110; Total number of losses: 54; Total Number of normals: 324.
Somatic mutations of MAFF:
Generating mutation plots.
Highly correlated genes for MAFF:
Showing top 20/686 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| MAFF | GRIK2 | 0.756662 | 3 | 0 | 3 |
| MAFF | CAMK2A | 0.719568 | 4 | 0 | 3 |
| MAFF | ZNF626 | 0.716623 | 3 | 0 | 3 |
| MAFF | NOL3 | 0.714655 | 3 | 0 | 3 |
| MAFF | KIAA0408 | 0.707961 | 4 | 0 | 3 |
| MAFF | GRPR | 0.706872 | 3 | 0 | 3 |
| MAFF | SLC25A25 | 0.704842 | 4 | 0 | 4 |
| MAFF | PIM1 | 0.69528 | 11 | 0 | 11 |
| MAFF | DUSP5 | 0.690989 | 12 | 0 | 11 |
| MAFF | ZFP36 | 0.688553 | 10 | 0 | 8 |
| MAFF | PDLIM2 | 0.686617 | 9 | 0 | 9 |
| MAFF | ATP6V1C2 | 0.686218 | 4 | 0 | 3 |
| MAFF | VASN | 0.685246 | 6 | 0 | 6 |
| MAFF | PHACTR2 | 0.684595 | 9 | 0 | 9 |
| MAFF | CSRNP1 | 0.67885 | 8 | 0 | 8 |
| MAFF | SERTAD1 | 0.674675 | 5 | 0 | 5 |
| MAFF | MGLL | 0.671948 | 11 | 0 | 10 |
| MAFF | PCA3 | 0.671397 | 3 | 0 | 3 |
| MAFF | ADAL | 0.670771 | 3 | 0 | 3 |
| MAFF | YOD1 | 0.669013 | 10 | 0 | 10 |
For details and further investigation, click here
