| Full name: ZFP36 ring finger protein | Alias Symbol: RNF162A|TIS11|G0S24|TTP|NUP475 | ||
| Type: protein-coding gene | Cytoband: 19q13.1 | ||
| Entrez ID: 7538 | HGNC ID: HGNC:12862 | Ensembl Gene: ENSG00000128016 | OMIM ID: 190700 |
| Drug and gene relationship at DGIdb | |||
Expression of ZFP36:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | ZFP36 | 7538 | 201531_at | -1.0743 | 0.2900 | |
| GSE20347 | ZFP36 | 7538 | 201531_at | -1.1806 | 0.0001 | |
| GSE23400 | ZFP36 | 7538 | 201531_at | -1.1355 | 0.0000 | |
| GSE26886 | ZFP36 | 7538 | 201531_at | -1.6162 | 0.0000 | |
| GSE29001 | ZFP36 | 7538 | 201531_at | -1.3508 | 0.0004 | |
| GSE38129 | ZFP36 | 7538 | 201531_at | -1.4782 | 0.0000 | |
| GSE45670 | ZFP36 | 7538 | 201531_at | -0.8655 | 0.0058 | |
| GSE63941 | ZFP36 | 7538 | 201531_at | -0.3018 | 0.6123 | |
| GSE77861 | ZFP36 | 7538 | 201531_at | -0.5727 | 0.2278 | |
| GSE97050 | ZFP36 | 7538 | A_23_P39237 | -0.6910 | 0.2157 | |
| SRP007169 | ZFP36 | 7538 | RNAseq | -3.5842 | 0.0000 | |
| SRP008496 | ZFP36 | 7538 | RNAseq | -3.0717 | 0.0000 | |
| SRP064894 | ZFP36 | 7538 | RNAseq | -1.4691 | 0.0000 | |
| SRP133303 | ZFP36 | 7538 | RNAseq | -0.9926 | 0.0008 | |
| SRP159526 | ZFP36 | 7538 | RNAseq | -1.0666 | 0.0477 | |
| SRP193095 | ZFP36 | 7538 | RNAseq | -0.9317 | 0.0013 | |
| SRP219564 | ZFP36 | 7538 | RNAseq | -0.5720 | 0.2174 | |
| TCGA | ZFP36 | 7538 | RNAseq | -0.2041 | 0.0173 |
Upregulated datasets: 0; Downregulated datasets: 9.
Survival by ZFP36 expression:
 |
| TCGA |
Note: Click image to view full size file.
Copy number change of ZFP36:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | ZFP36 | 7538 | 7 | 4 | 19 | |
| GSE20123 | ZFP36 | 7538 | 7 | 3 | 20 | |
| GSE43470 | ZFP36 | 7538 | 3 | 11 | 29 | |
| GSE46452 | ZFP36 | 7538 | 48 | 1 | 10 | |
| GSE47630 | ZFP36 | 7538 | 9 | 5 | 26 | |
| GSE54993 | ZFP36 | 7538 | 17 | 3 | 50 | |
| GSE54994 | ZFP36 | 7538 | 7 | 9 | 37 | |
| GSE60625 | ZFP36 | 7538 | 9 | 0 | 2 | |
| GSE74703 | ZFP36 | 7538 | 3 | 7 | 26 | |
| GSE74704 | ZFP36 | 7538 | 7 | 1 | 12 | |
| TCGA | ZFP36 | 7538 | 14 | 16 | 66 |
Total number of gains: 131; Total number of losses: 60; Total Number of normals: 297.
Somatic mutations of ZFP36:
Generating mutation plots.
Highly correlated genes for ZFP36:
Showing top 20/588 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| ZFP36 | RDH5 | 0.790364 | 3 | 0 | 3 |
| ZFP36 | DUSP1 | 0.762575 | 11 | 0 | 10 |
| ZFP36 | CSRNP1 | 0.742021 | 6 | 0 | 5 |
| ZFP36 | C9orf47 | 0.698027 | 3 | 0 | 3 |
| ZFP36 | MAFF | 0.688553 | 10 | 0 | 8 |
| ZFP36 | JUNB | 0.687232 | 11 | 0 | 9 |
| ZFP36 | KCNE1 | 0.683441 | 3 | 0 | 3 |
| ZFP36 | PADI1 | 0.680763 | 7 | 0 | 7 |
| ZFP36 | C5orf66-AS1 | 0.68055 | 3 | 0 | 3 |
| ZFP36 | FOSB | 0.680343 | 10 | 0 | 8 |
| ZFP36 | CYSRT1 | 0.671659 | 4 | 0 | 3 |
| ZFP36 | WNK4 | 0.664738 | 3 | 0 | 3 |
| ZFP36 | ULK3 | 0.66304 | 3 | 0 | 3 |
| ZFP36 | KLF6 | 0.662781 | 11 | 0 | 9 |
| ZFP36 | CRYAB | 0.657497 | 9 | 0 | 8 |
| ZFP36 | TOB1 | 0.653524 | 9 | 0 | 8 |
| ZFP36 | ABLIM1 | 0.652447 | 7 | 0 | 6 |
| ZFP36 | DUSP5 | 0.650948 | 9 | 0 | 7 |
| ZFP36 | TJP1 | 0.650297 | 8 | 0 | 8 |
| ZFP36 | GRPR | 0.649991 | 4 | 0 | 3 |
For details and further investigation, click here
