| Full name: mastermind like transcriptional coactivator 1 | Alias Symbol: KIAA0200|Mam-1 | ||
| Type: protein-coding gene | Cytoband: 5q35.3 | ||
| Entrez ID: 9794 | HGNC ID: HGNC:13632 | Ensembl Gene: ENSG00000161021 | OMIM ID: 605424 |
| Drug and gene relationship at DGIdb | |||
MAML1 involved pathways:
| KEGG pathway | Description | View |
|---|---|---|
| hsa04330 | Notch signaling pathway |
Expression of MAML1:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | MAML1 | 9794 | 202360_at | 0.3983 | 0.1301 | |
| GSE20347 | MAML1 | 9794 | 202360_at | 0.2015 | 0.0588 | |
| GSE23400 | MAML1 | 9794 | 202360_at | 0.2077 | 0.0001 | |
| GSE26886 | MAML1 | 9794 | 202360_at | 0.6741 | 0.0012 | |
| GSE29001 | MAML1 | 9794 | 202360_at | 0.2002 | 0.1953 | |
| GSE38129 | MAML1 | 9794 | 202360_at | 0.1563 | 0.1314 | |
| GSE45670 | MAML1 | 9794 | 202360_at | 0.0733 | 0.5012 | |
| GSE53622 | MAML1 | 9794 | 70436 | 0.3024 | 0.0000 | |
| GSE53624 | MAML1 | 9794 | 70436 | 0.2879 | 0.0000 | |
| GSE63941 | MAML1 | 9794 | 202360_at | 0.3571 | 0.2959 | |
| GSE77861 | MAML1 | 9794 | 202360_at | 0.4357 | 0.0177 | |
| GSE97050 | MAML1 | 9794 | A_33_P3220149 | 0.0146 | 0.9552 | |
| SRP007169 | MAML1 | 9794 | RNAseq | 0.0259 | 0.9470 | |
| SRP008496 | MAML1 | 9794 | RNAseq | -0.3132 | 0.1883 | |
| SRP064894 | MAML1 | 9794 | RNAseq | -0.0011 | 0.9947 | |
| SRP133303 | MAML1 | 9794 | RNAseq | 0.2736 | 0.0732 | |
| SRP159526 | MAML1 | 9794 | RNAseq | 0.2854 | 0.3715 | |
| SRP193095 | MAML1 | 9794 | RNAseq | 0.2394 | 0.0332 | |
| SRP219564 | MAML1 | 9794 | RNAseq | 0.2113 | 0.4734 | |
| TCGA | MAML1 | 9794 | RNAseq | 0.0190 | 0.6729 |
Upregulated datasets: 0; Downregulated datasets: 0.
Survival by MAML1 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of MAML1:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | MAML1 | 9794 | 2 | 12 | 16 | |
| GSE20123 | MAML1 | 9794 | 2 | 12 | 16 | |
| GSE43470 | MAML1 | 9794 | 1 | 11 | 31 | |
| GSE46452 | MAML1 | 9794 | 0 | 27 | 32 | |
| GSE47630 | MAML1 | 9794 | 1 | 20 | 19 | |
| GSE54993 | MAML1 | 9794 | 10 | 2 | 58 | |
| GSE54994 | MAML1 | 9794 | 2 | 17 | 34 | |
| GSE60625 | MAML1 | 9794 | 1 | 0 | 10 | |
| GSE74703 | MAML1 | 9794 | 1 | 7 | 28 | |
| GSE74704 | MAML1 | 9794 | 1 | 6 | 13 | |
| TCGA | MAML1 | 9794 | 11 | 34 | 51 |
Total number of gains: 32; Total number of losses: 148; Total Number of normals: 308.
Somatic mutations of MAML1:
Generating mutation plots.
Highly correlated genes for MAML1:
Showing top 20/1003 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| MAML1 | LRRC58 | 0.767468 | 4 | 0 | 4 |
| MAML1 | YWHAG | 0.767277 | 3 | 0 | 3 |
| MAML1 | GNA13 | 0.759836 | 3 | 0 | 3 |
| MAML1 | CCNJ | 0.756985 | 3 | 0 | 3 |
| MAML1 | UHRF1BP1 | 0.751911 | 3 | 0 | 3 |
| MAML1 | TAF1C | 0.724986 | 3 | 0 | 3 |
| MAML1 | WDR81 | 0.720393 | 3 | 0 | 3 |
| MAML1 | TERF2IP | 0.713789 | 3 | 0 | 3 |
| MAML1 | NOM1 | 0.711628 | 4 | 0 | 4 |
| MAML1 | POLR3C | 0.707458 | 3 | 0 | 3 |
| MAML1 | FIP1L1 | 0.706054 | 3 | 0 | 3 |
| MAML1 | C1orf226 | 0.703212 | 3 | 0 | 3 |
| MAML1 | ACBD6 | 0.699272 | 4 | 0 | 4 |
| MAML1 | FBXL19 | 0.692097 | 3 | 0 | 3 |
| MAML1 | USP42 | 0.690788 | 4 | 0 | 4 |
| MAML1 | AGAP1 | 0.688516 | 3 | 0 | 3 |
| MAML1 | PIK3R3 | 0.684183 | 4 | 0 | 3 |
| MAML1 | PBXIP1 | 0.683365 | 3 | 0 | 3 |
| MAML1 | UHMK1 | 0.682356 | 5 | 0 | 4 |
| MAML1 | GPR107 | 0.680681 | 3 | 0 | 3 |
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