| Full name: membrane bound O-acyltransferase domain containing 2 | Alias Symbol: FLJ14415|FLJ90298 | ||
| Type: protein-coding gene | Cytoband: 2p25.1 | ||
| Entrez ID: 129642 | HGNC ID: HGNC:25193 | Ensembl Gene: ENSG00000143797 | OMIM ID: 611949 |
| Drug and gene relationship at DGIdb | |||
Expression of MBOAT2:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | MBOAT2 | 129642 | 226726_at | -0.8278 | 0.4370 | |
| GSE20347 | MBOAT2 | 129642 | 213288_at | -0.8711 | 0.0001 | |
| GSE23400 | MBOAT2 | 129642 | 213288_at | -0.4324 | 0.0000 | |
| GSE26886 | MBOAT2 | 129642 | 226726_at | -2.2297 | 0.0000 | |
| GSE29001 | MBOAT2 | 129642 | 213288_at | -0.8176 | 0.0126 | |
| GSE38129 | MBOAT2 | 129642 | 213288_at | -0.5065 | 0.0627 | |
| GSE45670 | MBOAT2 | 129642 | 226726_at | 0.0484 | 0.8983 | |
| GSE53622 | MBOAT2 | 129642 | 135921 | -0.3950 | 0.0014 | |
| GSE53624 | MBOAT2 | 129642 | 135921 | -0.7098 | 0.0000 | |
| GSE63941 | MBOAT2 | 129642 | 226726_at | -1.2212 | 0.1237 | |
| GSE77861 | MBOAT2 | 129642 | 226726_at | -0.6326 | 0.0781 | |
| GSE97050 | MBOAT2 | 129642 | A_24_P114255 | -0.0028 | 0.9932 | |
| SRP007169 | MBOAT2 | 129642 | RNAseq | -1.7809 | 0.0000 | |
| SRP008496 | MBOAT2 | 129642 | RNAseq | -1.6962 | 0.0000 | |
| SRP064894 | MBOAT2 | 129642 | RNAseq | -1.1953 | 0.0000 | |
| SRP133303 | MBOAT2 | 129642 | RNAseq | -0.3804 | 0.0948 | |
| SRP159526 | MBOAT2 | 129642 | RNAseq | -0.8773 | 0.0215 | |
| SRP193095 | MBOAT2 | 129642 | RNAseq | -0.7472 | 0.0018 | |
| SRP219564 | MBOAT2 | 129642 | RNAseq | -0.5876 | 0.3938 | |
| TCGA | MBOAT2 | 129642 | RNAseq | 0.2715 | 0.0395 |
Upregulated datasets: 0; Downregulated datasets: 4.
Survival by MBOAT2 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of MBOAT2:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | MBOAT2 | 129642 | 10 | 2 | 18 | |
| GSE20123 | MBOAT2 | 129642 | 10 | 2 | 18 | |
| GSE43470 | MBOAT2 | 129642 | 2 | 1 | 40 | |
| GSE46452 | MBOAT2 | 129642 | 3 | 4 | 52 | |
| GSE47630 | MBOAT2 | 129642 | 7 | 0 | 33 | |
| GSE54993 | MBOAT2 | 129642 | 0 | 7 | 63 | |
| GSE54994 | MBOAT2 | 129642 | 11 | 0 | 42 | |
| GSE60625 | MBOAT2 | 129642 | 0 | 3 | 8 | |
| GSE74703 | MBOAT2 | 129642 | 2 | 0 | 34 | |
| GSE74704 | MBOAT2 | 129642 | 9 | 1 | 10 | |
| TCGA | MBOAT2 | 129642 | 35 | 5 | 56 |
Total number of gains: 89; Total number of losses: 25; Total Number of normals: 374.
Somatic mutations of MBOAT2:
Generating mutation plots.
Highly correlated genes for MBOAT2:
Showing top 20/995 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| MBOAT2 | UBE2D2 | 0.788045 | 4 | 0 | 4 |
| MBOAT2 | SLC16A14 | 0.78456 | 3 | 0 | 3 |
| MBOAT2 | APOB | 0.783595 | 3 | 0 | 3 |
| MBOAT2 | LRRC28 | 0.778103 | 3 | 0 | 3 |
| MBOAT2 | IMPACT | 0.747115 | 3 | 0 | 3 |
| MBOAT2 | PPM1K | 0.74144 | 4 | 0 | 4 |
| MBOAT2 | ARL16 | 0.736622 | 3 | 0 | 3 |
| MBOAT2 | PXMP4 | 0.732413 | 3 | 0 | 3 |
| MBOAT2 | ACTR2 | 0.72623 | 5 | 0 | 5 |
| MBOAT2 | WBP2 | 0.723115 | 4 | 0 | 4 |
| MBOAT2 | SULT2B1 | 0.722698 | 8 | 0 | 8 |
| MBOAT2 | CAPNS2 | 0.721321 | 4 | 0 | 4 |
| MBOAT2 | HDHD2 | 0.715194 | 3 | 0 | 3 |
| MBOAT2 | CSNK1G3 | 0.714774 | 3 | 0 | 3 |
| MBOAT2 | ID1 | 0.711245 | 3 | 0 | 3 |
| MBOAT2 | UBE2E2 | 0.707782 | 4 | 0 | 3 |
| MBOAT2 | GJB2 | 0.703274 | 4 | 0 | 3 |
| MBOAT2 | CSDE1 | 0.702805 | 3 | 0 | 3 |
| MBOAT2 | ZNF185 | 0.702616 | 9 | 0 | 8 |
| MBOAT2 | SIAE | 0.69737 | 4 | 0 | 3 |
For details and further investigation, click here
