| Full name: patatin like phospholipase domain containing 4 | Alias Symbol: DXS1283E|GS2|iPLA2eta | ||
| Type: protein-coding gene | Cytoband: Xp22.31 | ||
| Entrez ID: 8228 | HGNC ID: HGNC:24887 | Ensembl Gene: ENSG00000006757 | OMIM ID: 300102 |
| Drug and gene relationship at DGIdb | |||
Expression of PNPLA4:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | PNPLA4 | 8228 | 209739_s_at | -0.1856 | 0.8164 | |
| GSE20347 | PNPLA4 | 8228 | 209739_s_at | -0.8468 | 0.0006 | |
| GSE23400 | PNPLA4 | 8228 | 209739_s_at | -0.1188 | 0.0387 | |
| GSE26886 | PNPLA4 | 8228 | 209739_s_at | -0.9934 | 0.0002 | |
| GSE29001 | PNPLA4 | 8228 | 209739_s_at | -0.4079 | 0.2473 | |
| GSE38129 | PNPLA4 | 8228 | 209739_s_at | -0.5843 | 0.0040 | |
| GSE45670 | PNPLA4 | 8228 | 209739_s_at | -0.3040 | 0.1555 | |
| GSE53622 | PNPLA4 | 8228 | 46856 | -1.1416 | 0.0000 | |
| GSE53624 | PNPLA4 | 8228 | 46856 | -1.1292 | 0.0000 | |
| GSE63941 | PNPLA4 | 8228 | 209739_s_at | 0.6296 | 0.3823 | |
| GSE77861 | PNPLA4 | 8228 | 209739_s_at | -0.4326 | 0.0256 | |
| SRP007169 | PNPLA4 | 8228 | RNAseq | -1.3201 | 0.0230 | |
| SRP008496 | PNPLA4 | 8228 | RNAseq | -1.3856 | 0.0000 | |
| SRP064894 | PNPLA4 | 8228 | RNAseq | -0.4900 | 0.0672 | |
| SRP133303 | PNPLA4 | 8228 | RNAseq | -0.0415 | 0.8161 | |
| SRP159526 | PNPLA4 | 8228 | RNAseq | -0.5656 | 0.0622 | |
| SRP193095 | PNPLA4 | 8228 | RNAseq | -0.3617 | 0.0007 | |
| SRP219564 | PNPLA4 | 8228 | RNAseq | -0.5422 | 0.3134 | |
| TCGA | PNPLA4 | 8228 | RNAseq | -0.3577 | 0.0001 |
Upregulated datasets: 0; Downregulated datasets: 4.
Survival by PNPLA4 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of PNPLA4:
No record found for this gene.
Somatic mutations of PNPLA4:
Generating mutation plots.
Highly correlated genes for PNPLA4:
Showing top 20/578 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| PNPLA4 | SDHB | 0.729391 | 3 | 0 | 3 |
| PNPLA4 | MRPS11 | 0.71554 | 4 | 0 | 3 |
| PNPLA4 | VDAC3 | 0.698031 | 3 | 0 | 3 |
| PNPLA4 | NRAP | 0.677105 | 3 | 0 | 3 |
| PNPLA4 | A2ML1 | 0.675722 | 3 | 0 | 3 |
| PNPLA4 | FAM83D | 0.67062 | 3 | 0 | 3 |
| PNPLA4 | DENND2C | 0.664887 | 3 | 0 | 3 |
| PNPLA4 | ANKRD22 | 0.658298 | 3 | 0 | 3 |
| PNPLA4 | CERS3 | 0.654181 | 4 | 0 | 3 |
| PNPLA4 | CD9 | 0.651715 | 3 | 0 | 3 |
| PNPLA4 | DYNLL1 | 0.645453 | 6 | 0 | 6 |
| PNPLA4 | OXSM | 0.640294 | 6 | 0 | 5 |
| PNPLA4 | HMGCS1 | 0.638825 | 5 | 0 | 4 |
| PNPLA4 | MRPL23 | 0.638634 | 5 | 0 | 4 |
| PNPLA4 | ABHD17C | 0.636762 | 4 | 0 | 3 |
| PNPLA4 | MCHR2 | 0.634787 | 3 | 0 | 3 |
| PNPLA4 | DHRS7B | 0.634531 | 3 | 0 | 3 |
| PNPLA4 | SYAP1 | 0.633977 | 7 | 0 | 6 |
| PNPLA4 | NACA | 0.632324 | 4 | 0 | 3 |
| PNPLA4 | LRRC61 | 0.632258 | 3 | 0 | 3 |
For details and further investigation, click here
