| Full name: MyoD family inhibitor | Alias Symbol: I-mfa | ||
| Type: protein-coding gene | Cytoband: 6p21.1 | ||
| Entrez ID: 4188 | HGNC ID: HGNC:6967 | Ensembl Gene: ENSG00000112559 | OMIM ID: 604971 |
| Drug and gene relationship at DGIdb | |||
Expression of MDFI:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | MDFI | 4188 | 205375_at | 0.4857 | 0.5143 | |
| GSE20347 | MDFI | 4188 | 205375_at | -0.0777 | 0.4456 | |
| GSE23400 | MDFI | 4188 | 205375_at | 0.0199 | 0.8334 | |
| GSE26886 | MDFI | 4188 | 205375_at | 0.2805 | 0.0339 | |
| GSE29001 | MDFI | 4188 | 205375_at | -0.1100 | 0.6531 | |
| GSE38129 | MDFI | 4188 | 205375_at | 0.1822 | 0.3042 | |
| GSE45670 | MDFI | 4188 | 205375_at | 0.4972 | 0.0014 | |
| GSE53622 | MDFI | 4188 | 72727 | 0.2230 | 0.0005 | |
| GSE53624 | MDFI | 4188 | 72727 | 0.1136 | 0.1481 | |
| GSE63941 | MDFI | 4188 | 205375_at | 0.8948 | 0.0139 | |
| GSE77861 | MDFI | 4188 | 205375_at | 0.1365 | 0.6145 | |
| GSE97050 | MDFI | 4188 | A_33_P3246418 | -0.1046 | 0.6741 | |
| SRP007169 | MDFI | 4188 | RNAseq | -0.8228 | 0.0313 | |
| SRP008496 | MDFI | 4188 | RNAseq | -0.4563 | 0.1383 | |
| SRP064894 | MDFI | 4188 | RNAseq | 0.6556 | 0.0192 | |
| SRP133303 | MDFI | 4188 | RNAseq | 0.8201 | 0.0127 | |
| SRP219564 | MDFI | 4188 | RNAseq | 0.5938 | 0.3916 | |
| TCGA | MDFI | 4188 | RNAseq | 1.0323 | 0.0000 |
Upregulated datasets: 1; Downregulated datasets: 0.
Survival by MDFI expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of MDFI:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | MDFI | 4188 | 6 | 1 | 23 | |
| GSE20123 | MDFI | 4188 | 6 | 1 | 23 | |
| GSE43470 | MDFI | 4188 | 6 | 0 | 37 | |
| GSE46452 | MDFI | 4188 | 2 | 9 | 48 | |
| GSE47630 | MDFI | 4188 | 8 | 4 | 28 | |
| GSE54993 | MDFI | 4188 | 3 | 2 | 65 | |
| GSE54994 | MDFI | 4188 | 11 | 4 | 38 | |
| GSE60625 | MDFI | 4188 | 0 | 1 | 10 | |
| GSE74703 | MDFI | 4188 | 6 | 0 | 30 | |
| GSE74704 | MDFI | 4188 | 3 | 1 | 16 | |
| TCGA | MDFI | 4188 | 21 | 13 | 62 |
Total number of gains: 72; Total number of losses: 36; Total Number of normals: 380.
Somatic mutations of MDFI:
Generating mutation plots.
Highly correlated genes for MDFI:
Showing top 20/261 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| MDFI | SPTAN1 | 0.766851 | 3 | 0 | 3 |
| MDFI | PIP5K1A | 0.735635 | 3 | 0 | 3 |
| MDFI | NRL | 0.719971 | 4 | 0 | 4 |
| MDFI | LINC00520 | 0.717886 | 3 | 0 | 3 |
| MDFI | LEPROTL1 | 0.694409 | 3 | 0 | 3 |
| MDFI | FAM83B | 0.693505 | 3 | 0 | 3 |
| MDFI | RCOR2 | 0.691335 | 3 | 0 | 3 |
| MDFI | TAOK2 | 0.678989 | 5 | 0 | 5 |
| MDFI | SH3BP1 | 0.678485 | 6 | 0 | 6 |
| MDFI | CDRT15 | 0.674765 | 3 | 0 | 3 |
| MDFI | GCM2 | 0.6745 | 5 | 0 | 5 |
| MDFI | RAPGEF3 | 0.67024 | 4 | 0 | 4 |
| MDFI | CC2D1B | 0.668287 | 3 | 0 | 3 |
| MDFI | BNC1 | 0.667336 | 4 | 0 | 3 |
| MDFI | DCTN1 | 0.665911 | 4 | 0 | 3 |
| MDFI | LEMD2 | 0.664822 | 3 | 0 | 3 |
| MDFI | CDH24 | 0.663376 | 4 | 0 | 3 |
| MDFI | TMEM54 | 0.653254 | 4 | 0 | 3 |
| MDFI | SLC25A53 | 0.650353 | 3 | 0 | 3 |
| MDFI | PLA2G4F | 0.648279 | 3 | 0 | 3 |
For details and further investigation, click here
