| Full name: multiple EGF like domains 9 | Alias Symbol: | ||
| Type: protein-coding gene | Cytoband: 9q33.2 | ||
| Entrez ID: 1955 | HGNC ID: HGNC:3234 | Ensembl Gene: ENSG00000106780 | OMIM ID: 604268 |
| Drug and gene relationship at DGIdb | |||
Expression of MEGF9:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | MEGF9 | 1955 | 212830_at | -0.8951 | 0.1075 | |
| GSE20347 | MEGF9 | 1955 | 212830_at | -1.0721 | 0.0003 | |
| GSE23400 | MEGF9 | 1955 | 212830_at | -0.4517 | 0.0003 | |
| GSE26886 | MEGF9 | 1955 | 212830_at | -1.0878 | 0.0081 | |
| GSE29001 | MEGF9 | 1955 | 212830_at | -1.2122 | 0.0050 | |
| GSE38129 | MEGF9 | 1955 | 212830_at | -0.8079 | 0.0006 | |
| GSE45670 | MEGF9 | 1955 | 212830_at | -0.5132 | 0.0474 | |
| GSE53622 | MEGF9 | 1955 | 63258 | -0.9208 | 0.0000 | |
| GSE53624 | MEGF9 | 1955 | 63258 | -0.9511 | 0.0000 | |
| GSE63941 | MEGF9 | 1955 | 212830_at | -2.7306 | 0.0168 | |
| GSE77861 | MEGF9 | 1955 | 212830_at | -0.7012 | 0.1859 | |
| GSE97050 | MEGF9 | 1955 | A_32_P129894 | -1.0313 | 0.0631 | |
| SRP007169 | MEGF9 | 1955 | RNAseq | -0.9996 | 0.0725 | |
| SRP008496 | MEGF9 | 1955 | RNAseq | -0.5535 | 0.0790 | |
| SRP064894 | MEGF9 | 1955 | RNAseq | -1.3708 | 0.0000 | |
| SRP133303 | MEGF9 | 1955 | RNAseq | -0.7320 | 0.0002 | |
| SRP159526 | MEGF9 | 1955 | RNAseq | 0.1616 | 0.5503 | |
| SRP193095 | MEGF9 | 1955 | RNAseq | -0.7640 | 0.0007 | |
| SRP219564 | MEGF9 | 1955 | RNAseq | -1.1146 | 0.0436 | |
| TCGA | MEGF9 | 1955 | RNAseq | -0.0219 | 0.8089 |
Upregulated datasets: 0; Downregulated datasets: 6.
Survival by MEGF9 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of MEGF9:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | MEGF9 | 1955 | 4 | 7 | 19 | |
| GSE20123 | MEGF9 | 1955 | 4 | 7 | 19 | |
| GSE43470 | MEGF9 | 1955 | 5 | 4 | 34 | |
| GSE46452 | MEGF9 | 1955 | 6 | 13 | 40 | |
| GSE47630 | MEGF9 | 1955 | 3 | 16 | 21 | |
| GSE54993 | MEGF9 | 1955 | 3 | 3 | 64 | |
| GSE54994 | MEGF9 | 1955 | 9 | 10 | 34 | |
| GSE60625 | MEGF9 | 1955 | 0 | 0 | 11 | |
| GSE74703 | MEGF9 | 1955 | 5 | 3 | 28 | |
| GSE74704 | MEGF9 | 1955 | 2 | 5 | 13 | |
| TCGA | MEGF9 | 1955 | 27 | 25 | 44 |
Total number of gains: 68; Total number of losses: 93; Total Number of normals: 327.
Somatic mutations of MEGF9:
Generating mutation plots.
Highly correlated genes for MEGF9:
Showing top 20/1147 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| MEGF9 | GBP6 | 0.766164 | 4 | 0 | 4 |
| MEGF9 | CYP4F3 | 0.73757 | 11 | 0 | 11 |
| MEGF9 | TALDO1 | 0.734589 | 11 | 0 | 11 |
| MEGF9 | KDM3A | 0.72925 | 4 | 0 | 4 |
| MEGF9 | PTGR1 | 0.723515 | 9 | 0 | 8 |
| MEGF9 | HUS1 | 0.717405 | 3 | 0 | 3 |
| MEGF9 | HBP1 | 0.717352 | 9 | 0 | 9 |
| MEGF9 | ATG4A | 0.714144 | 6 | 0 | 5 |
| MEGF9 | SENP8 | 0.714018 | 3 | 0 | 3 |
| MEGF9 | TMEM246 | 0.709207 | 9 | 0 | 9 |
| MEGF9 | GPBP1 | 0.70235 | 3 | 0 | 3 |
| MEGF9 | SAMD5 | 0.700824 | 9 | 0 | 9 |
| MEGF9 | PPIP5K2 | 0.700341 | 6 | 0 | 6 |
| MEGF9 | DRAM2 | 0.69906 | 3 | 0 | 3 |
| MEGF9 | SLC22A15 | 0.698382 | 5 | 0 | 5 |
| MEGF9 | MTMR10 | 0.697025 | 7 | 0 | 6 |
| MEGF9 | CCNYL1 | 0.696643 | 5 | 0 | 4 |
| MEGF9 | C11orf54 | 0.696102 | 4 | 0 | 4 |
| MEGF9 | LYSMD3 | 0.695536 | 5 | 0 | 4 |
| MEGF9 | PGD | 0.6955 | 11 | 0 | 11 |
For details and further investigation, click here
