| Full name: transmembrane protein 246 | Alias Symbol: MGC12992 | ||
| Type: protein-coding gene | Cytoband: 9q31.1 | ||
| Entrez ID: 84302 | HGNC ID: HGNC:28180 | Ensembl Gene: ENSG00000165152 | OMIM ID: |
Expression of TMEM246:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | TMEM246 | 84302 | 224458_at | -0.8357 | 0.2928 | |
| GSE20347 | TMEM246 | 84302 | 213386_at | -1.3137 | 0.0000 | |
| GSE23400 | TMEM246 | 84302 | 213386_at | -0.5991 | 0.0000 | |
| GSE26886 | TMEM246 | 84302 | 224458_at | -0.9083 | 0.0108 | |
| GSE29001 | TMEM246 | 84302 | 213386_at | -0.9189 | 0.0035 | |
| GSE38129 | TMEM246 | 84302 | 213386_at | -1.2313 | 0.0000 | |
| GSE45670 | TMEM246 | 84302 | 224458_at | -0.4364 | 0.0770 | |
| GSE53622 | TMEM246 | 84302 | 146958 | -1.1019 | 0.0000 | |
| GSE53624 | TMEM246 | 84302 | 146958 | -0.8837 | 0.0000 | |
| GSE63941 | TMEM246 | 84302 | 224458_at | 1.1425 | 0.4967 | |
| GSE77861 | TMEM246 | 84302 | 224458_at | -0.0625 | 0.7138 |
Upregulated datasets: 0; Downregulated datasets: 3.
Survival by TMEM246 expression:
 |  |
| GSE53622 | GSE53624 |
Note: Click image to view full size file.
Copy number change of TMEM246:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | TMEM246 | 84302 | 4 | 10 | 16 | |
| GSE20123 | TMEM246 | 84302 | 5 | 9 | 16 | |
| GSE43470 | TMEM246 | 84302 | 6 | 3 | 34 | |
| GSE46452 | TMEM246 | 84302 | 6 | 13 | 40 | |
| GSE47630 | TMEM246 | 84302 | 1 | 17 | 22 | |
| GSE54993 | TMEM246 | 84302 | 3 | 3 | 64 | |
| GSE54994 | TMEM246 | 84302 | 9 | 11 | 33 | |
| GSE60625 | TMEM246 | 84302 | 0 | 0 | 11 | |
| GSE74703 | TMEM246 | 84302 | 5 | 3 | 28 | |
| GSE74704 | TMEM246 | 84302 | 2 | 6 | 12 | |
| TCGA | TMEM246 | 84302 | 28 | 21 | 47 |
Total number of gains: 69; Total number of losses: 96; Total Number of normals: 323.
Somatic mutations of TMEM246:
Generating mutation plots.
Highly correlated genes for TMEM246:
Showing top 20/708 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| TMEM246 | MEGF9 | 0.709207 | 9 | 0 | 9 |
| TMEM246 | GALNT12 | 0.701804 | 9 | 0 | 9 |
| TMEM246 | MANSC1 | 0.699411 | 9 | 0 | 8 |
| TMEM246 | ZDHHC3 | 0.695625 | 10 | 0 | 10 |
| TMEM246 | ADH7 | 0.694133 | 10 | 0 | 9 |
| TMEM246 | TALDO1 | 0.687198 | 7 | 0 | 7 |
| TMEM246 | ALDH3A1 | 0.67669 | 10 | 0 | 10 |
| TMEM246 | PPP2R5A | 0.673175 | 9 | 0 | 8 |
| TMEM246 | PPL | 0.672338 | 10 | 0 | 10 |
| TMEM246 | NUCB2 | 0.671176 | 9 | 0 | 9 |
| TMEM246 | PTGR1 | 0.661679 | 6 | 0 | 5 |
| TMEM246 | CEACAM5 | 0.660452 | 10 | 0 | 10 |
| TMEM246 | CYP2C18 | 0.658652 | 10 | 0 | 9 |
| TMEM246 | MGLL | 0.656452 | 10 | 0 | 10 |
| TMEM246 | ELOVL6 | 0.656269 | 10 | 0 | 10 |
| TMEM246 | SCNN1A | 0.65609 | 9 | 0 | 9 |
| TMEM246 | BAIAP2 | 0.655571 | 8 | 0 | 8 |
| TMEM246 | CES2 | 0.652334 | 7 | 0 | 7 |
| TMEM246 | FLG-AS1 | 0.651968 | 5 | 0 | 5 |
| TMEM246 | RHOG | 0.647383 | 4 | 0 | 3 |
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