| Full name: cytochrome P450 family 4 subfamily F member 3 | Alias Symbol: CYP4F | ||
| Type: protein-coding gene | Cytoband: 19p13.12 | ||
| Entrez ID: 4051 | HGNC ID: HGNC:2646 | Ensembl Gene: ENSG00000186529 | OMIM ID: 601270 |
| Drug and gene relationship at DGIdb | |||
Expression of CYP4F3:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | CYP4F3 | 4051 | 206515_at | -2.4069 | 0.1542 | |
| GSE20347 | CYP4F3 | 4051 | 206515_at | -1.6458 | 0.0042 | |
| GSE23400 | CYP4F3 | 4051 | 206515_at | -0.5148 | 0.0766 | |
| GSE26886 | CYP4F3 | 4051 | 206515_at | -2.4924 | 0.0072 | |
| GSE29001 | CYP4F3 | 4051 | 206515_at | -2.4886 | 0.0039 | |
| GSE38129 | CYP4F3 | 4051 | 206515_at | -0.8697 | 0.1572 | |
| GSE45670 | CYP4F3 | 4051 | 206515_at | -1.0243 | 0.1650 | |
| GSE53622 | CYP4F3 | 4051 | 20325 | -1.8566 | 0.0000 | |
| GSE53624 | CYP4F3 | 4051 | 20325 | -1.6240 | 0.0000 | |
| GSE63941 | CYP4F3 | 4051 | 206515_at | 1.9633 | 0.2490 | |
| GSE77861 | CYP4F3 | 4051 | 206515_at | -0.6605 | 0.5148 | |
| SRP007169 | CYP4F3 | 4051 | RNAseq | -0.0709 | 0.9361 | |
| SRP008496 | CYP4F3 | 4051 | RNAseq | 0.1623 | 0.8606 | |
| SRP064894 | CYP4F3 | 4051 | RNAseq | -1.6694 | 0.0020 | |
| SRP133303 | CYP4F3 | 4051 | RNAseq | -1.5940 | 0.0000 | |
| SRP159526 | CYP4F3 | 4051 | RNAseq | 1.2975 | 0.1809 | |
| SRP193095 | CYP4F3 | 4051 | RNAseq | 0.1078 | 0.7904 | |
| SRP219564 | CYP4F3 | 4051 | RNAseq | -0.3912 | 0.7375 | |
| TCGA | CYP4F3 | 4051 | RNAseq | 0.4239 | 0.3654 |
Upregulated datasets: 0; Downregulated datasets: 7.
Survival by CYP4F3 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of CYP4F3:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | CYP4F3 | 4051 | 4 | 2 | 24 | |
| GSE20123 | CYP4F3 | 4051 | 3 | 1 | 26 | |
| GSE43470 | CYP4F3 | 4051 | 2 | 5 | 36 | |
| GSE46452 | CYP4F3 | 4051 | 47 | 1 | 11 | |
| GSE47630 | CYP4F3 | 4051 | 4 | 7 | 29 | |
| GSE54993 | CYP4F3 | 4051 | 15 | 4 | 51 | |
| GSE54994 | CYP4F3 | 4051 | 6 | 14 | 33 | |
| GSE60625 | CYP4F3 | 4051 | 9 | 0 | 2 | |
| GSE74703 | CYP4F3 | 4051 | 2 | 4 | 30 | |
| GSE74704 | CYP4F3 | 4051 | 0 | 1 | 19 | |
| TCGA | CYP4F3 | 4051 | 20 | 10 | 66 |
Total number of gains: 112; Total number of losses: 49; Total Number of normals: 327.
Somatic mutations of CYP4F3:
Generating mutation plots.
Highly correlated genes for CYP4F3:
Showing top 20/488 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| CYP4F3 | CYP4F2 | 0.816292 | 12 | 0 | 12 |
| CYP4F3 | ALDH3A1 | 0.813706 | 12 | 0 | 12 |
| CYP4F3 | PTGR1 | 0.766784 | 7 | 0 | 7 |
| CYP4F3 | TALDO1 | 0.757492 | 10 | 0 | 9 |
| CYP4F3 | ADH7 | 0.741475 | 12 | 0 | 12 |
| CYP4F3 | SERPINB3 | 0.741063 | 4 | 0 | 4 |
| CYP4F3 | MEGF9 | 0.73757 | 11 | 0 | 11 |
| CYP4F3 | PGD | 0.720227 | 12 | 0 | 12 |
| CYP4F3 | ALDH3A2 | 0.708285 | 12 | 0 | 12 |
| CYP4F3 | AKR1B10 | 0.702597 | 11 | 0 | 11 |
| CYP4F3 | HK1 | 0.697167 | 11 | 0 | 10 |
| CYP4F3 | TSPAN7 | 0.691371 | 11 | 0 | 11 |
| CYP4F3 | GSTA4 | 0.671302 | 10 | 0 | 9 |
| CYP4F3 | NQO1 | 0.666772 | 10 | 0 | 9 |
| CYP4F3 | SUSD4 | 0.665406 | 10 | 0 | 10 |
| CYP4F3 | NAMPT | 0.661432 | 11 | 0 | 11 |
| CYP4F3 | EPHX1 | 0.6613 | 11 | 0 | 10 |
| CYP4F3 | ME1 | 0.657235 | 12 | 0 | 10 |
| CYP4F3 | CES1 | 0.654075 | 12 | 0 | 11 |
| CYP4F3 | CBR3 | 0.653958 | 12 | 0 | 10 |
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