| Full name: transmembrane and immunoglobulin domain containing 2 | Alias Symbol: MGC23244|CD28H|IGPR-1 | ||
| Type: protein-coding gene | Cytoband: 19p13.3 | ||
| Entrez ID: 126259 | HGNC ID: HGNC:28324 | Ensembl Gene: ENSG00000167664 | OMIM ID: 614715 |
| Drug and gene relationship at DGIdb | |||
Expression of TMIGD2:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | TMIGD2 | 126259 | 244716_x_at | -0.1108 | 0.5383 | |
| GSE26886 | TMIGD2 | 126259 | 244716_x_at | 0.0379 | 0.7584 | |
| GSE45670 | TMIGD2 | 126259 | 244716_x_at | -0.0091 | 0.9363 | |
| GSE53622 | TMIGD2 | 126259 | 88179 | -0.3251 | 0.0087 | |
| GSE53624 | TMIGD2 | 126259 | 88179 | -0.3476 | 0.0014 | |
| GSE63941 | TMIGD2 | 126259 | 244716_x_at | 0.1721 | 0.4577 | |
| GSE77861 | TMIGD2 | 126259 | 244716_x_at | -0.0118 | 0.9325 | |
| GSE97050 | TMIGD2 | 126259 | A_33_P3415698 | 0.1393 | 0.4552 | |
| SRP133303 | TMIGD2 | 126259 | RNAseq | -0.0988 | 0.7712 | |
| SRP219564 | TMIGD2 | 126259 | RNAseq | -0.4765 | 0.5036 | |
| TCGA | TMIGD2 | 126259 | RNAseq | 0.2183 | 0.7270 |
Upregulated datasets: 0; Downregulated datasets: 0.
Survival by TMIGD2 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of TMIGD2:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | TMIGD2 | 126259 | 5 | 3 | 22 | |
| GSE20123 | TMIGD2 | 126259 | 4 | 2 | 24 | |
| GSE43470 | TMIGD2 | 126259 | 1 | 8 | 34 | |
| GSE46452 | TMIGD2 | 126259 | 47 | 1 | 11 | |
| GSE47630 | TMIGD2 | 126259 | 5 | 7 | 28 | |
| GSE54993 | TMIGD2 | 126259 | 16 | 3 | 51 | |
| GSE54994 | TMIGD2 | 126259 | 6 | 16 | 31 | |
| GSE60625 | TMIGD2 | 126259 | 9 | 0 | 2 | |
| GSE74703 | TMIGD2 | 126259 | 1 | 5 | 30 | |
| GSE74704 | TMIGD2 | 126259 | 1 | 2 | 17 | |
| TCGA | TMIGD2 | 126259 | 11 | 18 | 67 |
Total number of gains: 106; Total number of losses: 65; Total Number of normals: 317.
Somatic mutations of TMIGD2:
Generating mutation plots.
Highly correlated genes for TMIGD2:
Showing top 20/42 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| TMIGD2 | IQCD | 0.744433 | 3 | 0 | 3 |
| TMIGD2 | CD247 | 0.742172 | 3 | 0 | 3 |
| TMIGD2 | FXYD2 | 0.740995 | 3 | 0 | 3 |
| TMIGD2 | IL17RC | 0.727999 | 3 | 0 | 3 |
| TMIGD2 | MFNG | 0.705371 | 3 | 0 | 3 |
| TMIGD2 | IL21 | 0.693349 | 3 | 0 | 3 |
| TMIGD2 | CARD9 | 0.684804 | 3 | 0 | 3 |
| TMIGD2 | TNRC6C-AS1 | 0.651605 | 3 | 0 | 3 |
| TMIGD2 | PRF1 | 0.636617 | 3 | 0 | 3 |
| TMIGD2 | ZNF226 | 0.628296 | 3 | 0 | 3 |
| TMIGD2 | RGL4 | 0.624868 | 4 | 0 | 3 |
| TMIGD2 | S1PR4 | 0.623317 | 3 | 0 | 3 |
| TMIGD2 | STAP1 | 0.59307 | 3 | 0 | 3 |
| TMIGD2 | MS4A1 | 0.591578 | 3 | 0 | 3 |
| TMIGD2 | CD52 | 0.588813 | 4 | 0 | 3 |
| TMIGD2 | FBF1 | 0.586524 | 4 | 0 | 3 |
| TMIGD2 | PDIA2 | 0.583485 | 4 | 0 | 3 |
| TMIGD2 | ZNF831 | 0.58189 | 4 | 0 | 3 |
| TMIGD2 | CNGB1 | 0.579992 | 6 | 0 | 4 |
| TMIGD2 | MASP2 | 0.576755 | 4 | 0 | 3 |
For details and further investigation, click here
