| Full name: major facilitator superfamily domain containing 12 | Alias Symbol: MGC20700|PP3501 | ||
| Type: protein-coding gene | Cytoband: 19p13.3 | ||
| Entrez ID: 126321 | HGNC ID: HGNC:28299 | Ensembl Gene: ENSG00000161091 | OMIM ID: 617745 |
Expression of MFSD12:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | MFSD12 | 126321 | 226516_at | 0.3039 | 0.2777 | |
| GSE20347 | MFSD12 | 126321 | 220178_at | 0.7136 | 0.0003 | |
| GSE23400 | MFSD12 | 126321 | 220178_at | 0.1875 | 0.0005 | |
| GSE26886 | MFSD12 | 126321 | 226516_at | 0.2498 | 0.0733 | |
| GSE29001 | MFSD12 | 126321 | 220178_at | 0.4080 | 0.0315 | |
| GSE38129 | MFSD12 | 126321 | 220178_at | 0.5819 | 0.0005 | |
| GSE45670 | MFSD12 | 126321 | 226516_at | 0.0464 | 0.7557 | |
| GSE53622 | MFSD12 | 126321 | 17225 | 0.8842 | 0.0000 | |
| GSE53624 | MFSD12 | 126321 | 17225 | 1.3450 | 0.0000 | |
| GSE63941 | MFSD12 | 126321 | 226516_at | -0.0813 | 0.6430 | |
| GSE77861 | MFSD12 | 126321 | 226516_at | -0.0503 | 0.8233 | |
| SRP007169 | MFSD12 | 126321 | RNAseq | 1.1998 | 0.0145 | |
| SRP008496 | MFSD12 | 126321 | RNAseq | 1.1296 | 0.0011 | |
| SRP064894 | MFSD12 | 126321 | RNAseq | 1.4181 | 0.0000 | |
| SRP133303 | MFSD12 | 126321 | RNAseq | 0.8770 | 0.0000 | |
| SRP159526 | MFSD12 | 126321 | RNAseq | 0.6102 | 0.0122 | |
| SRP193095 | MFSD12 | 126321 | RNAseq | 1.2549 | 0.0000 | |
| SRP219564 | MFSD12 | 126321 | RNAseq | 1.7172 | 0.0017 |
Upregulated datasets: 6; Downregulated datasets: 0.
Survival by MFSD12 expression:
 |  |
| GSE53622 | GSE53624 |
Note: Click image to view full size file.
Copy number change of MFSD12:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | MFSD12 | 126321 | 5 | 4 | 21 | |
| GSE20123 | MFSD12 | 126321 | 4 | 3 | 23 | |
| GSE43470 | MFSD12 | 126321 | 1 | 9 | 33 | |
| GSE46452 | MFSD12 | 126321 | 47 | 1 | 11 | |
| GSE47630 | MFSD12 | 126321 | 5 | 7 | 28 | |
| GSE54993 | MFSD12 | 126321 | 16 | 3 | 51 | |
| GSE54994 | MFSD12 | 126321 | 8 | 16 | 29 | |
| GSE60625 | MFSD12 | 126321 | 9 | 0 | 2 | |
| GSE74703 | MFSD12 | 126321 | 1 | 6 | 29 | |
| GSE74704 | MFSD12 | 126321 | 1 | 3 | 16 | |
| TCGA | MFSD12 | 126321 | 10 | 19 | 67 |
Total number of gains: 107; Total number of losses: 71; Total Number of normals: 310.
Somatic mutations of MFSD12:
Generating mutation plots.
Highly correlated genes for MFSD12:
Showing top 20/750 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| MFSD12 | NSUN2 | 0.692759 | 3 | 0 | 3 |
| MFSD12 | TMEM102 | 0.681608 | 3 | 0 | 3 |
| MFSD12 | GPR84 | 0.679127 | 3 | 0 | 3 |
| MFSD12 | C1QTNF6 | 0.673266 | 5 | 0 | 4 |
| MFSD12 | SLC25A32 | 0.670988 | 5 | 0 | 5 |
| MFSD12 | GALNT18 | 0.670487 | 3 | 0 | 3 |
| MFSD12 | FHOD1 | 0.670237 | 9 | 0 | 8 |
| MFSD12 | SPRED3 | 0.667701 | 3 | 0 | 3 |
| MFSD12 | PPP1R18 | 0.665381 | 4 | 0 | 4 |
| MFSD12 | NDUFB9 | 0.665293 | 3 | 0 | 3 |
| MFSD12 | ACY1 | 0.66331 | 3 | 0 | 3 |
| MFSD12 | ZNF469 | 0.662407 | 4 | 0 | 3 |
| MFSD12 | RIMS4 | 0.66105 | 4 | 0 | 3 |
| MFSD12 | CTPS1 | 0.660101 | 4 | 0 | 3 |
| MFSD12 | LRRC10B | 0.657519 | 3 | 0 | 3 |
| MFSD12 | TMEM138 | 0.653973 | 3 | 0 | 3 |
| MFSD12 | SYCE1L | 0.651491 | 3 | 0 | 3 |
| MFSD12 | CHERP | 0.650192 | 5 | 0 | 4 |
| MFSD12 | BAIAP2L2 | 0.648055 | 4 | 0 | 3 |
| MFSD12 | CCM2 | 0.645334 | 4 | 0 | 4 |
For details and further investigation, click here
