| Full name: G protein-coupled receptor 84 | Alias Symbol: EX33 | ||
| Type: protein-coding gene | Cytoband: 12q13.13 | ||
| Entrez ID: 53831 | HGNC ID: HGNC:4535 | Ensembl Gene: ENSG00000139572 | OMIM ID: 606383 |
| Drug and gene relationship at DGIdb | |||
Expression of GPR84:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | GPR84 | 53831 | 223767_at | 0.5968 | 0.2419 | |
| GSE26886 | GPR84 | 53831 | 223767_at | -0.0961 | 0.6837 | |
| GSE45670 | GPR84 | 53831 | 223767_at | 0.6903 | 0.0001 | |
| GSE53622 | GPR84 | 53831 | 59323 | 1.2061 | 0.0000 | |
| GSE53624 | GPR84 | 53831 | 59323 | 1.2450 | 0.0000 | |
| GSE63941 | GPR84 | 53831 | 223767_at | 0.2433 | 0.1046 | |
| GSE77861 | GPR84 | 53831 | 223767_at | 0.1218 | 0.2394 | |
| GSE97050 | GPR84 | 53831 | A_23_P25155 | 0.2454 | 0.3381 | |
| SRP064894 | GPR84 | 53831 | RNAseq | 2.1911 | 0.0000 | |
| SRP133303 | GPR84 | 53831 | RNAseq | 1.5208 | 0.0007 | |
| TCGA | GPR84 | 53831 | RNAseq | 2.3285 | 0.0000 |
Upregulated datasets: 5; Downregulated datasets: 0.
Survival by GPR84 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of GPR84:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | GPR84 | 53831 | 4 | 1 | 25 | |
| GSE20123 | GPR84 | 53831 | 4 | 1 | 25 | |
| GSE43470 | GPR84 | 53831 | 3 | 0 | 40 | |
| GSE46452 | GPR84 | 53831 | 7 | 1 | 51 | |
| GSE47630 | GPR84 | 53831 | 10 | 2 | 28 | |
| GSE54993 | GPR84 | 53831 | 0 | 5 | 65 | |
| GSE54994 | GPR84 | 53831 | 4 | 1 | 48 | |
| GSE60625 | GPR84 | 53831 | 0 | 0 | 11 | |
| GSE74703 | GPR84 | 53831 | 3 | 0 | 33 | |
| GSE74704 | GPR84 | 53831 | 3 | 1 | 16 | |
| TCGA | GPR84 | 53831 | 15 | 11 | 70 |
Total number of gains: 53; Total number of losses: 23; Total Number of normals: 412.
Somatic mutations of GPR84:
Generating mutation plots.
Highly correlated genes for GPR84:
Showing top 20/574 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| GPR84 | LRRC15 | 0.760151 | 3 | 0 | 3 |
| GPR84 | CCRL2 | 0.744392 | 4 | 0 | 4 |
| GPR84 | ANGPT2 | 0.718233 | 4 | 0 | 4 |
| GPR84 | MCEMP1 | 0.70204 | 4 | 0 | 4 |
| GPR84 | C1QTNF6 | 0.700772 | 4 | 0 | 3 |
| GPR84 | TRAM2 | 0.691438 | 5 | 0 | 5 |
| GPR84 | ENPEP | 0.68969 | 3 | 0 | 3 |
| GPR84 | OLR1 | 0.689173 | 4 | 0 | 3 |
| GPR84 | IRF9 | 0.686471 | 3 | 0 | 3 |
| GPR84 | CLEC5A | 0.684445 | 4 | 0 | 3 |
| GPR84 | TDO2 | 0.682425 | 5 | 0 | 4 |
| GPR84 | RNASE2 | 0.68083 | 4 | 0 | 3 |
| GPR84 | MFSD12 | 0.679127 | 3 | 0 | 3 |
| GPR84 | FCER1G | 0.676744 | 5 | 0 | 4 |
| GPR84 | PPP1R18 | 0.676357 | 6 | 0 | 6 |
| GPR84 | SIGLEC12 | 0.671117 | 3 | 0 | 3 |
| GPR84 | NFKBIE | 0.665789 | 4 | 0 | 4 |
| GPR84 | FMNL2 | 0.663994 | 5 | 0 | 5 |
| GPR84 | MMP12 | 0.662917 | 7 | 0 | 6 |
| GPR84 | CHRNA1 | 0.662506 | 4 | 0 | 3 |
For details and further investigation, click here
