| Full name: leucine rich repeat containing 10B | Alias Symbol: | ||
| Type: protein-coding gene | Cytoband: 11q12.2 | ||
| Entrez ID: 390205 | HGNC ID: HGNC:37215 | Ensembl Gene: ENSG00000204950 | OMIM ID: |
| Drug and gene relationship at DGIdb | |||
Expression of LRRC10B:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | LRRC10B | 390205 | 236666_s_at | -0.1629 | 0.6051 | |
| GSE26886 | LRRC10B | 390205 | 236666_s_at | 0.1252 | 0.5815 | |
| GSE45670 | LRRC10B | 390205 | 236666_s_at | 0.0046 | 0.9789 | |
| GSE53622 | LRRC10B | 390205 | 11125 | 0.3367 | 0.0000 | |
| GSE53624 | LRRC10B | 390205 | 11125 | 0.4917 | 0.0000 | |
| GSE63941 | LRRC10B | 390205 | 236666_s_at | 0.1602 | 0.7744 | |
| GSE77861 | LRRC10B | 390205 | 236666_s_at | 0.0127 | 0.9466 | |
| GSE97050 | LRRC10B | 390205 | A_33_P3334348 | 0.3581 | 0.1920 | |
| SRP219564 | LRRC10B | 390205 | RNAseq | 0.0737 | 0.9241 | |
| TCGA | LRRC10B | 390205 | RNAseq | -0.4240 | 0.2011 |
Upregulated datasets: 0; Downregulated datasets: 0.
Survival by LRRC10B expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of LRRC10B:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | LRRC10B | 390205 | 4 | 5 | 21 | |
| GSE20123 | LRRC10B | 390205 | 4 | 5 | 21 | |
| GSE43470 | LRRC10B | 390205 | 2 | 6 | 35 | |
| GSE46452 | LRRC10B | 390205 | 8 | 4 | 47 | |
| GSE47630 | LRRC10B | 390205 | 3 | 8 | 29 | |
| GSE54993 | LRRC10B | 390205 | 3 | 0 | 67 | |
| GSE54994 | LRRC10B | 390205 | 5 | 5 | 43 | |
| GSE60625 | LRRC10B | 390205 | 0 | 3 | 8 | |
| GSE74703 | LRRC10B | 390205 | 2 | 3 | 31 | |
| GSE74704 | LRRC10B | 390205 | 3 | 3 | 14 | |
| TCGA | LRRC10B | 390205 | 15 | 10 | 71 |
Total number of gains: 49; Total number of losses: 52; Total Number of normals: 387.
Somatic mutations of LRRC10B:
Generating mutation plots.
Highly correlated genes for LRRC10B:
Showing top 20/112 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| LRRC10B | RNASE2 | 0.747442 | 3 | 0 | 3 |
| LRRC10B | SLC3A2 | 0.668955 | 3 | 0 | 3 |
| LRRC10B | PTHLH | 0.662499 | 3 | 0 | 3 |
| LRRC10B | MFSD12 | 0.657519 | 3 | 0 | 3 |
| LRRC10B | MMP1 | 0.653444 | 3 | 0 | 3 |
| LRRC10B | LAPTM4B | 0.626729 | 3 | 0 | 3 |
| LRRC10B | LILRB3 | 0.626165 | 3 | 0 | 3 |
| LRRC10B | INSM2 | 0.625022 | 3 | 0 | 3 |
| LRRC10B | DDX39A | 0.619114 | 3 | 0 | 3 |
| LRRC10B | DNAJB11 | 0.611644 | 3 | 0 | 3 |
| LRRC10B | FSCN1 | 0.61083 | 3 | 0 | 3 |
| LRRC10B | NME1 | 0.606719 | 3 | 0 | 3 |
| LRRC10B | CD163 | 0.605006 | 3 | 0 | 3 |
| LRRC10B | DNAI2 | 0.604898 | 3 | 0 | 3 |
| LRRC10B | KLHL17 | 0.604207 | 3 | 0 | 3 |
| LRRC10B | SERPINE1 | 0.603693 | 4 | 0 | 3 |
| LRRC10B | PSMB3 | 0.603578 | 3 | 0 | 3 |
| LRRC10B | VMP1 | 0.601387 | 3 | 0 | 3 |
| LRRC10B | HSP90AB1 | 0.60121 | 3 | 0 | 3 |
| LRRC10B | TFRC | 0.600489 | 3 | 0 | 3 |
For details and further investigation, click here
