| Full name: polypeptide N-acetylgalactosaminyltransferase 18 | Alias Symbol: MGC71806|GALNT15|GalNAc-T18 | ||
| Type: protein-coding gene | Cytoband: 11p15.4 | ||
| Entrez ID: 374378 | HGNC ID: HGNC:30488 | Ensembl Gene: ENSG00000110328 | OMIM ID: 615136 |
| Drug and gene relationship at DGIdb | |||
Expression of GALNT18:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | GALNT18 | 374378 | 1554079_at | 0.6409 | 0.3377 | |
| GSE26886 | GALNT18 | 374378 | 1554079_at | 1.9193 | 0.0000 | |
| GSE45670 | GALNT18 | 374378 | 1554079_at | 1.3258 | 0.0008 | |
| GSE53622 | GALNT18 | 374378 | 29712 | 1.2348 | 0.0000 | |
| GSE53624 | GALNT18 | 374378 | 29712 | 1.6704 | 0.0000 | |
| GSE63941 | GALNT18 | 374378 | 1554079_at | 1.0209 | 0.2086 | |
| GSE77861 | GALNT18 | 374378 | 1554079_at | 1.4384 | 0.0156 | |
| SRP007169 | GALNT18 | 374378 | RNAseq | 2.8124 | 0.0000 | |
| SRP008496 | GALNT18 | 374378 | RNAseq | 3.3333 | 0.0000 | |
| SRP064894 | GALNT18 | 374378 | RNAseq | 1.3626 | 0.0000 | |
| SRP133303 | GALNT18 | 374378 | RNAseq | 1.5825 | 0.0000 | |
| SRP159526 | GALNT18 | 374378 | RNAseq | 1.6071 | 0.0001 | |
| SRP193095 | GALNT18 | 374378 | RNAseq | 2.1305 | 0.0000 | |
| SRP219564 | GALNT18 | 374378 | RNAseq | 0.1250 | 0.8440 |
Upregulated datasets: 11; Downregulated datasets: 0.
Survival by GALNT18 expression:
 |  |
| GSE53622 | GSE53624 |
Note: Click image to view full size file.
Copy number change of GALNT18:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | GALNT18 | 374378 | 0 | 9 | 21 | |
| GSE20123 | GALNT18 | 374378 | 0 | 9 | 21 | |
| GSE43470 | GALNT18 | 374378 | 1 | 6 | 36 | |
| GSE46452 | GALNT18 | 374378 | 7 | 5 | 47 | |
| GSE47630 | GALNT18 | 374378 | 3 | 11 | 26 | |
| GSE54993 | GALNT18 | 374378 | 3 | 1 | 66 | |
| GSE54994 | GALNT18 | 374378 | 4 | 12 | 37 | |
| GSE60625 | GALNT18 | 374378 | 0 | 0 | 11 | |
| GSE74703 | GALNT18 | 374378 | 1 | 4 | 31 | |
| GSE74704 | GALNT18 | 374378 | 0 | 7 | 13 | |
| TCGA | GALNT18 | 374378 | 11 | 34 | 51 |
Total number of gains: 30; Total number of losses: 98; Total Number of normals: 360.
Somatic mutations of GALNT18:
Generating mutation plots.
Highly correlated genes for GALNT18:
Showing top 20/1548 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| GALNT18 | CPT1A | 0.810262 | 3 | 0 | 3 |
| GALNT18 | WDR54 | 0.80374 | 6 | 0 | 6 |
| GALNT18 | SLC38A6 | 0.782532 | 3 | 0 | 3 |
| GALNT18 | GNA12 | 0.776641 | 6 | 0 | 6 |
| GALNT18 | XPR1 | 0.775038 | 6 | 0 | 6 |
| GALNT18 | RAB32 | 0.764771 | 6 | 0 | 6 |
| GALNT18 | ACVR1 | 0.757583 | 6 | 0 | 6 |
| GALNT18 | SH3PXD2B | 0.756476 | 6 | 0 | 6 |
| GALNT18 | TGFBI | 0.750384 | 6 | 0 | 6 |
| GALNT18 | TMEM184B | 0.749577 | 6 | 0 | 6 |
| GALNT18 | SLCO1B3 | 0.748623 | 3 | 0 | 3 |
| GALNT18 | ARPC1B | 0.746565 | 6 | 0 | 6 |
| GALNT18 | C11orf24 | 0.741506 | 6 | 0 | 6 |
| GALNT18 | SLC3A2 | 0.739956 | 6 | 0 | 6 |
| GALNT18 | EXT1 | 0.737909 | 5 | 0 | 5 |
| GALNT18 | FSCN1 | 0.736741 | 7 | 0 | 7 |
| GALNT18 | LRP12 | 0.736282 | 6 | 0 | 6 |
| GALNT18 | FMNL2 | 0.736172 | 6 | 0 | 6 |
| GALNT18 | SERPINH1 | 0.735801 | 6 | 0 | 6 |
| GALNT18 | LRRC8D | 0.735701 | 6 | 0 | 6 |
For details and further investigation, click here
