| Full name: formin homology 2 domain containing 1 | Alias Symbol: FHOS | ||
| Type: protein-coding gene | Cytoband: 16q22.1 | ||
| Entrez ID: 29109 | HGNC ID: HGNC:17905 | Ensembl Gene: ENSG00000135723 | OMIM ID: 606881 |
| Drug and gene relationship at DGIdb | |||
Expression of FHOD1:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | FHOD1 | 29109 | 218530_at | 0.9773 | 0.0541 | |
| GSE20347 | FHOD1 | 29109 | 218530_at | 0.7832 | 0.0000 | |
| GSE23400 | FHOD1 | 29109 | 218530_at | 0.4907 | 0.0000 | |
| GSE26886 | FHOD1 | 29109 | 218530_at | 0.6610 | 0.0001 | |
| GSE29001 | FHOD1 | 29109 | 218530_at | 0.4287 | 0.0048 | |
| GSE38129 | FHOD1 | 29109 | 218530_at | 0.5842 | 0.0000 | |
| GSE45670 | FHOD1 | 29109 | 218530_at | 0.5598 | 0.0030 | |
| GSE53622 | FHOD1 | 29109 | 96507 | 0.8127 | 0.0000 | |
| GSE53624 | FHOD1 | 29109 | 96507 | 0.9940 | 0.0000 | |
| GSE63941 | FHOD1 | 29109 | 218530_at | -0.7176 | 0.0765 | |
| GSE77861 | FHOD1 | 29109 | 218530_at | 0.2577 | 0.1097 | |
| GSE97050 | FHOD1 | 29109 | A_23_P37778 | 0.4145 | 0.2948 | |
| SRP007169 | FHOD1 | 29109 | RNAseq | 2.1045 | 0.0001 | |
| SRP008496 | FHOD1 | 29109 | RNAseq | 1.8311 | 0.0000 | |
| SRP064894 | FHOD1 | 29109 | RNAseq | 1.2985 | 0.0000 | |
| SRP133303 | FHOD1 | 29109 | RNAseq | 0.5536 | 0.0016 | |
| SRP159526 | FHOD1 | 29109 | RNAseq | 1.0051 | 0.0064 | |
| SRP193095 | FHOD1 | 29109 | RNAseq | 1.3634 | 0.0000 | |
| SRP219564 | FHOD1 | 29109 | RNAseq | 1.0376 | 0.0041 | |
| TCGA | FHOD1 | 29109 | RNAseq | 0.2442 | 0.0003 |
Upregulated datasets: 6; Downregulated datasets: 0.
Survival by FHOD1 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of FHOD1:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | FHOD1 | 29109 | 9 | 2 | 19 | |
| GSE20123 | FHOD1 | 29109 | 9 | 2 | 19 | |
| GSE43470 | FHOD1 | 29109 | 1 | 9 | 33 | |
| GSE46452 | FHOD1 | 29109 | 38 | 1 | 20 | |
| GSE47630 | FHOD1 | 29109 | 10 | 8 | 22 | |
| GSE54993 | FHOD1 | 29109 | 2 | 4 | 64 | |
| GSE54994 | FHOD1 | 29109 | 8 | 10 | 35 | |
| GSE60625 | FHOD1 | 29109 | 4 | 0 | 7 | |
| GSE74703 | FHOD1 | 29109 | 1 | 6 | 29 | |
| GSE74704 | FHOD1 | 29109 | 5 | 1 | 14 | |
| TCGA | FHOD1 | 29109 | 29 | 12 | 55 |
Total number of gains: 116; Total number of losses: 55; Total Number of normals: 317.
Somatic mutations of FHOD1:
Generating mutation plots.
Highly correlated genes for FHOD1:
Showing top 20/1683 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| FHOD1 | ROMO1 | 0.789755 | 3 | 0 | 3 |
| FHOD1 | USB1 | 0.77658 | 11 | 0 | 11 |
| FHOD1 | WDR54 | 0.755521 | 7 | 0 | 7 |
| FHOD1 | FBLIM1 | 0.748982 | 7 | 0 | 7 |
| FHOD1 | TESK1 | 0.748029 | 3 | 0 | 3 |
| FHOD1 | SPON2 | 0.741135 | 3 | 0 | 3 |
| FHOD1 | LRRC8C | 0.736985 | 3 | 0 | 3 |
| FHOD1 | HOMER3 | 0.73595 | 12 | 0 | 11 |
| FHOD1 | FAM89A | 0.733201 | 3 | 0 | 3 |
| FHOD1 | MSN | 0.730898 | 11 | 0 | 11 |
| FHOD1 | ITGA3 | 0.730658 | 12 | 0 | 12 |
| FHOD1 | RTKN | 0.730193 | 7 | 0 | 7 |
| FHOD1 | PLEKHB2 | 0.723084 | 3 | 0 | 3 |
| FHOD1 | B3GNT9 | 0.721296 | 7 | 0 | 7 |
| FHOD1 | SERPINE1 | 0.720317 | 12 | 0 | 12 |
| FHOD1 | EBNA1BP2 | 0.718055 | 3 | 0 | 3 |
| FHOD1 | SH3PXD2B | 0.717933 | 8 | 0 | 8 |
| FHOD1 | MMP1 | 0.716105 | 11 | 0 | 10 |
| FHOD1 | ARPC1B | 0.714866 | 12 | 0 | 12 |
| FHOD1 | CCM2 | 0.714682 | 9 | 0 | 7 |
For details and further investigation, click here
