| Full name: hyaluronan synthase 2 | Alias Symbol: | ||
| Type: protein-coding gene | Cytoband: 8q24.13 | ||
| Entrez ID: 3037 | HGNC ID: HGNC:4819 | Ensembl Gene: ENSG00000170961 | OMIM ID: 601636 |
| Drug and gene relationship at DGIdb | |||
Expression of HAS2:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | HAS2 | 3037 | 230372_at | 0.4424 | 0.3972 | |
| GSE20347 | HAS2 | 3037 | 206432_at | 0.8741 | 0.0023 | |
| GSE23400 | HAS2 | 3037 | 206432_at | 0.3233 | 0.0015 | |
| GSE26886 | HAS2 | 3037 | 230372_at | 1.6036 | 0.0024 | |
| GSE29001 | HAS2 | 3037 | 206432_at | 1.1695 | 0.0256 | |
| GSE38129 | HAS2 | 3037 | 206432_at | 0.7741 | 0.0040 | |
| GSE45670 | HAS2 | 3037 | 230372_at | 0.2305 | 0.7285 | |
| GSE53622 | HAS2 | 3037 | 25472 | 1.2875 | 0.0000 | |
| GSE53624 | HAS2 | 3037 | 25472 | 1.4720 | 0.0000 | |
| GSE63941 | HAS2 | 3037 | 230372_at | -1.7311 | 0.0921 | |
| GSE77861 | HAS2 | 3037 | 230372_at | 0.2823 | 0.3505 | |
| GSE97050 | HAS2 | 3037 | A_23_P10206 | 0.9927 | 0.1316 | |
| SRP007169 | HAS2 | 3037 | RNAseq | 2.9584 | 0.0000 | |
| SRP008496 | HAS2 | 3037 | RNAseq | 3.9916 | 0.0000 | |
| SRP064894 | HAS2 | 3037 | RNAseq | 1.0250 | 0.0209 | |
| SRP133303 | HAS2 | 3037 | RNAseq | 1.4273 | 0.0000 | |
| SRP159526 | HAS2 | 3037 | RNAseq | 2.0895 | 0.0000 | |
| SRP193095 | HAS2 | 3037 | RNAseq | 3.3353 | 0.0000 | |
| SRP219564 | HAS2 | 3037 | RNAseq | 1.8624 | 0.0146 | |
| TCGA | HAS2 | 3037 | RNAseq | 0.1341 | 0.4689 |
Upregulated datasets: 11; Downregulated datasets: 0.
Survival by HAS2 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of HAS2:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | HAS2 | 3037 | 19 | 1 | 10 | |
| GSE20123 | HAS2 | 3037 | 20 | 1 | 9 | |
| GSE43470 | HAS2 | 3037 | 23 | 0 | 20 | |
| GSE46452 | HAS2 | 3037 | 27 | 0 | 32 | |
| GSE47630 | HAS2 | 3037 | 24 | 0 | 16 | |
| GSE54993 | HAS2 | 3037 | 0 | 21 | 49 | |
| GSE54994 | HAS2 | 3037 | 37 | 1 | 15 | |
| GSE60625 | HAS2 | 3037 | 0 | 4 | 7 | |
| GSE74703 | HAS2 | 3037 | 19 | 0 | 17 | |
| GSE74704 | HAS2 | 3037 | 13 | 1 | 6 | |
| TCGA | HAS2 | 3037 | 67 | 2 | 27 |
Total number of gains: 249; Total number of losses: 31; Total Number of normals: 208.
Somatic mutations of HAS2:
Generating mutation plots.
Highly correlated genes for HAS2:
Showing top 20/881 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| HAS2 | LRRC8C | 0.767445 | 3 | 0 | 3 |
| HAS2 | MGAT5 | 0.765005 | 4 | 0 | 4 |
| HAS2 | MSC | 0.758824 | 8 | 0 | 8 |
| HAS2 | MCM3AP | 0.746179 | 3 | 0 | 3 |
| HAS2 | ALPK2 | 0.72869 | 3 | 0 | 3 |
| HAS2 | GPX8 | 0.724305 | 6 | 0 | 6 |
| HAS2 | TNFAIP6 | 0.723013 | 12 | 0 | 11 |
| HAS2 | NNMT | 0.722941 | 3 | 0 | 3 |
| HAS2 | FCGR3A | 0.715116 | 3 | 0 | 3 |
| HAS2 | LRRC34 | 0.709592 | 3 | 0 | 3 |
| HAS2 | SLC35B1 | 0.693485 | 3 | 0 | 3 |
| HAS2 | CDH11 | 0.690248 | 13 | 0 | 12 |
| HAS2 | SLC6A15 | 0.687116 | 4 | 0 | 3 |
| HAS2 | MAPK6 | 0.686418 | 3 | 0 | 3 |
| HAS2 | SPON2 | 0.681545 | 3 | 0 | 3 |
| HAS2 | ADAMTS12 | 0.679544 | 8 | 0 | 8 |
| HAS2 | CHSY3 | 0.677054 | 7 | 0 | 6 |
| HAS2 | ANGPT2 | 0.67634 | 7 | 0 | 6 |
| HAS2 | PDCD1LG2 | 0.675824 | 5 | 0 | 4 |
| HAS2 | ELFN1 | 0.672994 | 4 | 0 | 3 |
For details and further investigation, click here
