TNFAIP6

 

Full name: TNF alpha induced protein 6 Alias Symbol: TSG6|TSG-6
Type: protein-coding gene Cytoband: 2q23.3
Entrez ID: 7130 HGNC ID: HGNC:11898 Ensembl Gene: ENSG00000123610 OMIM ID: 600410
Drug and gene relationship at DGIdb

 

Expression of TNFAIP6:

 

Dataset Gene EntrezID Probe Log2FC Adj.pValue Expression
GSE17351 TNFAIP6 7130 206026_s_at 1.3667 0.2614
GSE20347 TNFAIP6 7130 206025_s_at 2.2265 0.0000
GSE23400 TNFAIP6 7130 206026_s_at 0.5402 0.0000
GSE26886 TNFAIP6 7130 206025_s_at 1.4198 0.0008
GSE29001 TNFAIP6 7130 206026_s_at 1.2412 0.0084
GSE38129 TNFAIP6 7130 206025_s_at 1.9182 0.0000
GSE45670 TNFAIP6 7130 206026_s_at 0.4449 0.5354
GSE53622 TNFAIP6 7130 54732 2.3407 0.0000
GSE53624 TNFAIP6 7130 54732 2.6022 0.0000
GSE63941 TNFAIP6 7130 206025_s_at -6.0354 0.0000
GSE77861 TNFAIP6 7130 206025_s_at 0.6304 0.0456
GSE97050 TNFAIP6 7130 A_23_P165624 1.0930 0.1012
SRP007169 TNFAIP6 7130 RNAseq 5.5463 0.0000
SRP008496 TNFAIP6 7130 RNAseq 4.5738 0.0000
SRP064894 TNFAIP6 7130 RNAseq 2.0644 0.0001
SRP133303 TNFAIP6 7130 RNAseq 2.9058 0.0000
SRP193095 TNFAIP6 7130 RNAseq 5.0260 0.0000
SRP219564 TNFAIP6 7130 RNAseq 2.4160 0.0067
TCGA TNFAIP6 7130 RNAseq 0.7723 0.0001

Upregulated datasets: 12; Downregulated datasets: 1.  

 

Survival by TNFAIP6 expression:

 

GSE53622GSE53624TCGA

 

Note: Click image to view full size file.  

Copy number change of TNFAIP6:

 

Dataset Gene EntrezID Gain Loss Normal Detail
GSE15526 TNFAIP6 7130 3 2 25
GSE20123 TNFAIP6 7130 3 2 25
GSE43470 TNFAIP6 7130 3 1 39
GSE46452 TNFAIP6 7130 1 4 54
GSE47630 TNFAIP6 7130 5 3 32
GSE54993 TNFAIP6 7130 0 5 65
GSE54994 TNFAIP6 7130 11 2 40
GSE60625 TNFAIP6 7130 0 3 8
GSE74703 TNFAIP6 7130 2 1 33
GSE74704 TNFAIP6 7130 2 0 18
TCGA TNFAIP6 7130 20 8 68

Total number of gains: 50; Total number of losses: 31; Total Number of normals: 407.  

 

Somatic mutations of TNFAIP6:

 

Generating mutation plots.

 

Highly correlated genes for TNFAIP6:

 

Showing top 20/1384 corelated genes with mean PCC>0.5.
Gene1 Gene2 Mean PCC Num. Datasets Num. PCC<0 Num. PCC>0.5
TNFAIP6FCGR3A0.842764303
TNFAIP6LRRC8C0.810497303
TNFAIP6VCAN0.80141113013
TNFAIP6RAB340.800901303
TNFAIP6FADS10.799719303
TNFAIP6FAP0.78857311011
TNFAIP6COL6A30.78176613013
TNFAIP6CHN10.77763813013
TNFAIP6PDGFRB0.77481412012
TNFAIP6SPARC0.77368513013
TNFAIP6MRGPRF0.771608303
TNFAIP6CDH110.77053813013
TNFAIP6POSTN0.76866213012
TNFAIP6THY10.76773713013
TNFAIP6MMD0.76530113013
TNFAIP6COL3A10.76425712011
TNFAIP6CALU0.76332812011
TNFAIP6MGAT50.761198404
TNFAIP6C11orf960.75688404
TNFAIP6TK20.755952303

For details and further investigation, click here