| Full name: mitochondrial elongation factor 1 | Alias Symbol: FLJ20232|MiD51 | ||
| Type: protein-coding gene | Cytoband: 22q13.1 | ||
| Entrez ID: 54471 | HGNC ID: HGNC:25979 | Ensembl Gene: ENSG00000100335 | OMIM ID: 615497 |
| Drug and gene relationship at DGIdb | |||
Expression of MIEF1:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | MIEF1 | 54471 | 221516_s_at | 0.7657 | 0.0127 | |
| GSE20347 | MIEF1 | 54471 | 221516_s_at | 0.3237 | 0.0216 | |
| GSE23400 | MIEF1 | 54471 | 221516_s_at | 0.2202 | 0.0000 | |
| GSE26886 | MIEF1 | 54471 | 221516_s_at | -0.4147 | 0.0170 | |
| GSE29001 | MIEF1 | 54471 | 221516_s_at | 0.3071 | 0.3649 | |
| GSE38129 | MIEF1 | 54471 | 221516_s_at | 0.3278 | 0.0321 | |
| GSE45670 | MIEF1 | 54471 | 221516_s_at | 0.4348 | 0.0038 | |
| GSE53622 | MIEF1 | 54471 | 112616 | 0.2560 | 0.0000 | |
| GSE53624 | MIEF1 | 54471 | 150617 | 0.4666 | 0.0000 | |
| GSE63941 | MIEF1 | 54471 | 221516_s_at | 0.3439 | 0.3031 | |
| GSE77861 | MIEF1 | 54471 | 221516_s_at | 0.7243 | 0.0524 | |
| SRP007169 | MIEF1 | 54471 | RNAseq | 1.2619 | 0.0006 | |
| SRP008496 | MIEF1 | 54471 | RNAseq | 1.1072 | 0.0011 | |
| SRP064894 | MIEF1 | 54471 | RNAseq | 0.5152 | 0.0004 | |
| SRP133303 | MIEF1 | 54471 | RNAseq | 0.2179 | 0.1648 | |
| SRP159526 | MIEF1 | 54471 | RNAseq | 0.5046 | 0.0921 | |
| SRP193095 | MIEF1 | 54471 | RNAseq | 0.3342 | 0.0011 | |
| SRP219564 | MIEF1 | 54471 | RNAseq | 0.5362 | 0.1187 |
Upregulated datasets: 2; Downregulated datasets: 0.
Survival by MIEF1 expression:
 |  |
| GSE53622 | GSE53624 |
Note: Click image to view full size file.
Copy number change of MIEF1:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | MIEF1 | 54471 | 6 | 5 | 19 | |
| GSE20123 | MIEF1 | 54471 | 6 | 4 | 20 | |
| GSE43470 | MIEF1 | 54471 | 5 | 6 | 32 | |
| GSE46452 | MIEF1 | 54471 | 32 | 2 | 25 | |
| GSE47630 | MIEF1 | 54471 | 9 | 4 | 27 | |
| GSE54993 | MIEF1 | 54471 | 3 | 6 | 61 | |
| GSE54994 | MIEF1 | 54471 | 10 | 7 | 36 | |
| GSE60625 | MIEF1 | 54471 | 5 | 0 | 6 | |
| GSE74703 | MIEF1 | 54471 | 5 | 4 | 27 | |
| GSE74704 | MIEF1 | 54471 | 3 | 2 | 15 |
Total number of gains: 84; Total number of losses: 40; Total Number of normals: 268.
Somatic mutations of MIEF1:
Generating mutation plots.
Highly correlated genes for MIEF1:
Showing top 20/423 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| MIEF1 | POLR1A | 0.764462 | 3 | 0 | 3 |
| MIEF1 | TFR2 | 0.722811 | 3 | 0 | 3 |
| MIEF1 | BRI3BP | 0.703887 | 3 | 0 | 3 |
| MIEF1 | VMA21 | 0.689351 | 3 | 0 | 3 |
| MIEF1 | ELK4 | 0.678273 | 4 | 0 | 4 |
| MIEF1 | LRP8 | 0.675053 | 6 | 0 | 5 |
| MIEF1 | LRRC58 | 0.657372 | 3 | 0 | 3 |
| MIEF1 | CXXC1 | 0.656428 | 4 | 0 | 3 |
| MIEF1 | CDCA5 | 0.653918 | 5 | 0 | 4 |
| MIEF1 | TATDN2 | 0.651396 | 3 | 0 | 3 |
| MIEF1 | TSEN15 | 0.636372 | 4 | 0 | 4 |
| MIEF1 | PHF5A | 0.630865 | 7 | 0 | 4 |
| MIEF1 | SLC25A44 | 0.629946 | 5 | 0 | 3 |
| MIEF1 | TTK | 0.628423 | 8 | 0 | 7 |
| MIEF1 | TOP2A | 0.627629 | 8 | 0 | 8 |
| MIEF1 | CCDC117 | 0.626612 | 4 | 0 | 3 |
| MIEF1 | SLC25A17 | 0.623441 | 9 | 0 | 7 |
| MIEF1 | RAB3IP | 0.622187 | 4 | 0 | 3 |
| MIEF1 | NUFIP2 | 0.621444 | 3 | 0 | 3 |
| MIEF1 | SURF6 | 0.619833 | 3 | 0 | 3 |
For details and further investigation, click here
