| Full name: coiled-coil domain containing 117 | Alias Symbol: FLJ33814 | ||
| Type: protein-coding gene | Cytoband: 22q12.1 | ||
| Entrez ID: 150275 | HGNC ID: HGNC:26599 | Ensembl Gene: ENSG00000159873 | OMIM ID: |
| Drug and gene relationship at DGIdb | |||
Expression of CCDC117:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | CCDC117 | 150275 | 225644_at | 0.3625 | 0.3244 | |
| GSE26886 | CCDC117 | 150275 | 225644_at | -1.3182 | 0.0000 | |
| GSE45670 | CCDC117 | 150275 | 225644_at | 0.6082 | 0.0119 | |
| GSE63941 | CCDC117 | 150275 | 225644_at | -0.2112 | 0.5723 | |
| GSE77861 | CCDC117 | 150275 | 225644_at | 0.6727 | 0.0314 | |
| GSE97050 | CCDC117 | 150275 | A_23_P432034 | 0.3746 | 0.2049 | |
| SRP007169 | CCDC117 | 150275 | RNAseq | 1.0277 | 0.0010 | |
| SRP008496 | CCDC117 | 150275 | RNAseq | 0.8571 | 0.0002 | |
| SRP064894 | CCDC117 | 150275 | RNAseq | 0.3511 | 0.0212 | |
| SRP133303 | CCDC117 | 150275 | RNAseq | 0.4887 | 0.0005 | |
| SRP159526 | CCDC117 | 150275 | RNAseq | 0.6165 | 0.0011 | |
| SRP193095 | CCDC117 | 150275 | RNAseq | 0.2797 | 0.0062 | |
| SRP219564 | CCDC117 | 150275 | RNAseq | 0.2525 | 0.4161 | |
| TCGA | CCDC117 | 150275 | RNAseq | 0.0082 | 0.8723 |
Upregulated datasets: 1; Downregulated datasets: 1.
Survival by CCDC117 expression:
 |
| TCGA |
Note: Click image to view full size file.
Copy number change of CCDC117:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | CCDC117 | 150275 | 3 | 3 | 24 | |
| GSE20123 | CCDC117 | 150275 | 3 | 2 | 25 | |
| GSE43470 | CCDC117 | 150275 | 3 | 6 | 34 | |
| GSE46452 | CCDC117 | 150275 | 31 | 1 | 27 | |
| GSE47630 | CCDC117 | 150275 | 8 | 5 | 27 | |
| GSE54993 | CCDC117 | 150275 | 3 | 6 | 61 | |
| GSE54994 | CCDC117 | 150275 | 11 | 8 | 34 | |
| GSE60625 | CCDC117 | 150275 | 5 | 0 | 6 | |
| GSE74703 | CCDC117 | 150275 | 3 | 5 | 28 | |
| GSE74704 | CCDC117 | 150275 | 0 | 1 | 19 | |
| TCGA | CCDC117 | 150275 | 26 | 15 | 55 |
Total number of gains: 96; Total number of losses: 52; Total Number of normals: 340.
Somatic mutations of CCDC117:
Generating mutation plots.
Highly correlated genes for CCDC117:
Showing top 20/394 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| CCDC117 | RNPS1 | 0.797331 | 3 | 0 | 3 |
| CCDC117 | SNRNP40 | 0.773617 | 3 | 0 | 3 |
| CCDC117 | LAMTOR1 | 0.756332 | 3 | 0 | 3 |
| CCDC117 | TRIB2 | 0.751742 | 3 | 0 | 3 |
| CCDC117 | B4GALT4 | 0.748425 | 3 | 0 | 3 |
| CCDC117 | MCU | 0.748157 | 3 | 0 | 3 |
| CCDC117 | ARPC5 | 0.746739 | 3 | 0 | 3 |
| CCDC117 | C18orf54 | 0.742309 | 3 | 0 | 3 |
| CCDC117 | CCT4 | 0.733277 | 4 | 0 | 4 |
| CCDC117 | AMMECR1L | 0.732934 | 3 | 0 | 3 |
| CCDC117 | EZH2 | 0.729311 | 4 | 0 | 4 |
| CCDC117 | UTP20 | 0.725845 | 3 | 0 | 3 |
| CCDC117 | PLEKHG1 | 0.723101 | 3 | 0 | 3 |
| CCDC117 | MGAT2 | 0.721114 | 4 | 0 | 4 |
| CCDC117 | EMG1 | 0.719985 | 3 | 0 | 3 |
| CCDC117 | ABCF3 | 0.717687 | 3 | 0 | 3 |
| CCDC117 | SNX17 | 0.717184 | 3 | 0 | 3 |
| CCDC117 | RALGAPB | 0.713006 | 3 | 0 | 3 |
| CCDC117 | USP37 | 0.711786 | 5 | 0 | 5 |
| CCDC117 | SENP2 | 0.711603 | 4 | 0 | 4 |
For details and further investigation, click here
