PHF5A

 

Full name: PHD finger protein 5A Alias Symbol: MGC1346|SF3b14b|INI|bK223H9.2|Rds3|SAP14b|SF3B7
Type: protein-coding gene Cytoband: 22q13.2
Entrez ID: 84844 HGNC ID: HGNC:18000 Ensembl Gene: ENSG00000100410 OMIM ID: 617846
Drug and gene relationship at DGIdb

 

Expression of PHF5A:

 

Dataset Gene EntrezID Probe Log2FC Adj.pValue Expression
GSE17351 PHF5A 84844 225309_at 0.5717 0.0426
GSE26886 PHF5A 84844 225309_at 0.2549 0.2402
GSE45670 PHF5A 84844 225309_at 0.5311 0.0015
GSE53622 PHF5A 84844 139156 0.5033 0.0000
GSE53624 PHF5A 84844 139156 0.5352 0.0000
GSE63941 PHF5A 84844 225309_at 0.6883 0.0219
GSE77861 PHF5A 84844 225309_at 0.7478 0.0074
GSE97050 PHF5A 84844 A_23_P253571 0.5409 0.1296
SRP007169 PHF5A 84844 RNAseq 0.7049 0.0298
SRP008496 PHF5A 84844 RNAseq 0.6548 0.0167
SRP064894 PHF5A 84844 RNAseq 0.6099 0.0074
SRP133303 PHF5A 84844 RNAseq 0.5209 0.0067
SRP159526 PHF5A 84844 RNAseq 0.6192 0.0003
SRP193095 PHF5A 84844 RNAseq 0.2303 0.0951
SRP219564 PHF5A 84844 RNAseq 0.5730 0.1300
TCGA PHF5A 84844 RNAseq 0.2983 0.0000

Upregulated datasets: 0; Downregulated datasets: 0.  

 

Survival by PHF5A expression:

 

GSE53622GSE53624TCGA

 

Note: Click image to view full size file.  

Copy number change of PHF5A:

 

Dataset Gene EntrezID Gain Loss Normal Detail
GSE15526 PHF5A 84844 6 5 19
GSE20123 PHF5A 84844 6 4 20
GSE43470 PHF5A 84844 5 6 32
GSE46452 PHF5A 84844 31 2 26
GSE47630 PHF5A 84844 9 4 27
GSE54993 PHF5A 84844 3 6 61
GSE54994 PHF5A 84844 11 8 34
GSE60625 PHF5A 84844 5 0 6
GSE74703 PHF5A 84844 5 4 27
GSE74704 PHF5A 84844 3 2 15
TCGA PHF5A 84844 27 14 55

Total number of gains: 111; Total number of losses: 55; Total Number of normals: 322.  

 

Somatic mutations of PHF5A:

 

Generating mutation plots.

 

Highly correlated genes for PHF5A:

 

Showing top 20/1486 corelated genes with mean PCC>0.5.
Gene1 Gene2 Mean PCC Num. Datasets Num. PCC<0 Num. PCC>0.5
PHF5ADONSON0.800155404
PHF5APDPR0.784802303
PHF5ANUP430.775395303
PHF5AFAM32A0.767899303
PHF5APSMG30.764672505
PHF5AUSP420.761828404
PHF5APTCD30.758975404
PHF5AYWHAG0.75835404
PHF5ADSCC10.750034505
PHF5AA4GALT0.745181303
PHF5ASLC25A170.740135808
PHF5ACHST120.739177403
PHF5AMMS22L0.736163303
PHF5AINO80B0.734873303
PHF5ARNASEH10.729855707
PHF5ASETX0.729281303
PHF5ADTYMK0.728822505
PHF5AMAGOHB0.726979505
PHF5ACEP1520.725428404
PHF5ANIPA20.72462404

For details and further investigation, click here