| Full name: BRI3 binding protein | Alias Symbol: BNAS1|KG19|HCCR-2|HCCRBP-3 | ||
| Type: protein-coding gene | Cytoband: 12q24.31 | ||
| Entrez ID: 140707 | HGNC ID: HGNC:14251 | Ensembl Gene: ENSG00000184992 | OMIM ID: 615627 |
| Drug and gene relationship at DGIdb | |||
Screen Evidence:
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Expression of BRI3BP:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | BRI3BP | 140707 | 225716_at | 1.0842 | 0.1942 | |
| GSE26886 | BRI3BP | 140707 | 225716_at | -0.9520 | 0.0004 | |
| GSE45670 | BRI3BP | 140707 | 225716_at | 0.4542 | 0.0128 | |
| GSE53622 | BRI3BP | 140707 | 95407 | -0.0500 | 0.6104 | |
| GSE53624 | BRI3BP | 140707 | 95407 | 0.0650 | 0.5205 | |
| GSE63941 | BRI3BP | 140707 | 225716_at | 1.1307 | 0.0388 | |
| GSE77861 | BRI3BP | 140707 | 225716_at | 0.2989 | 0.1957 | |
| GSE97050 | BRI3BP | 140707 | A_32_P831181 | 0.7709 | 0.1752 | |
| SRP007169 | BRI3BP | 140707 | RNAseq | 0.4444 | 0.2770 | |
| SRP008496 | BRI3BP | 140707 | RNAseq | 0.0448 | 0.8354 | |
| SRP064894 | BRI3BP | 140707 | RNAseq | 0.2504 | 0.2466 | |
| SRP133303 | BRI3BP | 140707 | RNAseq | 0.3907 | 0.0677 | |
| SRP159526 | BRI3BP | 140707 | RNAseq | 0.4051 | 0.0751 | |
| SRP193095 | BRI3BP | 140707 | RNAseq | -0.1918 | 0.0841 | |
| SRP219564 | BRI3BP | 140707 | RNAseq | 0.3837 | 0.4394 | |
| TCGA | BRI3BP | 140707 | RNAseq | 0.2085 | 0.0155 |
Upregulated datasets: 1; Downregulated datasets: 0.
Survival by BRI3BP expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of BRI3BP:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | BRI3BP | 140707 | 4 | 5 | 21 | |
| GSE20123 | BRI3BP | 140707 | 4 | 5 | 21 | |
| GSE43470 | BRI3BP | 140707 | 2 | 0 | 41 | |
| GSE46452 | BRI3BP | 140707 | 9 | 1 | 49 | |
| GSE47630 | BRI3BP | 140707 | 9 | 3 | 28 | |
| GSE54993 | BRI3BP | 140707 | 0 | 5 | 65 | |
| GSE54994 | BRI3BP | 140707 | 4 | 8 | 41 | |
| GSE60625 | BRI3BP | 140707 | 0 | 0 | 11 | |
| GSE74703 | BRI3BP | 140707 | 2 | 0 | 34 | |
| GSE74704 | BRI3BP | 140707 | 2 | 3 | 15 | |
| TCGA | BRI3BP | 140707 | 21 | 12 | 63 |
Total number of gains: 57; Total number of losses: 42; Total Number of normals: 389.
Somatic mutations of BRI3BP:
Generating mutation plots.
Highly correlated genes for BRI3BP:
Showing top 20/273 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| BRI3BP | BROX | 0.794542 | 3 | 0 | 3 |
| BRI3BP | PPP2R1B | 0.727818 | 3 | 0 | 3 |
| BRI3BP | ETNK1 | 0.724349 | 3 | 0 | 3 |
| BRI3BP | UTP18 | 0.703968 | 3 | 0 | 3 |
| BRI3BP | MIEF1 | 0.703887 | 3 | 0 | 3 |
| BRI3BP | MKI67 | 0.695542 | 5 | 0 | 4 |
| BRI3BP | SRSF9 | 0.69046 | 3 | 0 | 3 |
| BRI3BP | POLR2B | 0.690395 | 3 | 0 | 3 |
| BRI3BP | RUSC1 | 0.680412 | 3 | 0 | 3 |
| BRI3BP | HNRNPF | 0.676859 | 4 | 0 | 4 |
| BRI3BP | GINS1 | 0.673692 | 5 | 0 | 5 |
| BRI3BP | RCC2 | 0.673345 | 4 | 0 | 3 |
| BRI3BP | SRSF10 | 0.673012 | 3 | 0 | 3 |
| BRI3BP | AASDH | 0.671178 | 3 | 0 | 3 |
| BRI3BP | TRUB1 | 0.670687 | 3 | 0 | 3 |
| BRI3BP | SFPQ | 0.669273 | 3 | 0 | 3 |
| BRI3BP | COTL1 | 0.666969 | 3 | 0 | 3 |
| BRI3BP | CA2 | 0.663172 | 3 | 0 | 3 |
| BRI3BP | CKAP2 | 0.661782 | 3 | 0 | 3 |
| BRI3BP | TSTA3 | 0.65643 | 4 | 0 | 3 |
For details and further investigation, click here
