| Full name: MYB binding protein 1a | Alias Symbol: P160|PAP2|FLJ37886|Pol5 | ||
| Type: protein-coding gene | Cytoband: 17p13.2 | ||
| Entrez ID: 10514 | HGNC ID: HGNC:7546 | Ensembl Gene: ENSG00000132382 | OMIM ID: 604885 |
| Drug and gene relationship at DGIdb | |||
Screen Evidence:
| |||
Expression of MYBBP1A:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | MYBBP1A | 10514 | 219098_at | 0.7500 | 0.0896 | |
| GSE20347 | MYBBP1A | 10514 | 219098_at | 0.2050 | 0.0778 | |
| GSE23400 | MYBBP1A | 10514 | 219098_at | 0.4849 | 0.0000 | |
| GSE26886 | MYBBP1A | 10514 | 219098_at | 0.8424 | 0.0000 | |
| GSE29001 | MYBBP1A | 10514 | 219098_at | 0.3331 | 0.1011 | |
| GSE38129 | MYBBP1A | 10514 | 219098_at | 0.3526 | 0.0061 | |
| GSE45670 | MYBBP1A | 10514 | 219098_at | 0.3351 | 0.0013 | |
| GSE53622 | MYBBP1A | 10514 | 116284 | 0.4984 | 0.0000 | |
| GSE53624 | MYBBP1A | 10514 | 149948 | 0.6857 | 0.0000 | |
| GSE63941 | MYBBP1A | 10514 | 219098_at | 0.6605 | 0.0338 | |
| GSE77861 | MYBBP1A | 10514 | 219098_at | 0.3176 | 0.0225 | |
| GSE97050 | MYBBP1A | 10514 | A_23_P78170 | 0.4354 | 0.2532 | |
| SRP007169 | MYBBP1A | 10514 | RNAseq | 0.9440 | 0.0210 | |
| SRP008496 | MYBBP1A | 10514 | RNAseq | 0.7000 | 0.0236 | |
| SRP064894 | MYBBP1A | 10514 | RNAseq | 0.1489 | 0.4096 | |
| SRP133303 | MYBBP1A | 10514 | RNAseq | -0.0997 | 0.4690 | |
| SRP159526 | MYBBP1A | 10514 | RNAseq | 0.4608 | 0.0861 | |
| SRP193095 | MYBBP1A | 10514 | RNAseq | 0.2535 | 0.0837 | |
| SRP219564 | MYBBP1A | 10514 | RNAseq | 0.4385 | 0.4111 | |
| TCGA | MYBBP1A | 10514 | RNAseq | 0.2336 | 0.0000 |
Upregulated datasets: 0; Downregulated datasets: 0.
Survival by MYBBP1A expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of MYBBP1A:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | MYBBP1A | 10514 | 5 | 2 | 23 | |
| GSE20123 | MYBBP1A | 10514 | 5 | 3 | 22 | |
| GSE43470 | MYBBP1A | 10514 | 1 | 6 | 36 | |
| GSE46452 | MYBBP1A | 10514 | 34 | 1 | 24 | |
| GSE47630 | MYBBP1A | 10514 | 7 | 1 | 32 | |
| GSE54993 | MYBBP1A | 10514 | 4 | 3 | 63 | |
| GSE54994 | MYBBP1A | 10514 | 5 | 9 | 39 | |
| GSE60625 | MYBBP1A | 10514 | 4 | 0 | 7 | |
| GSE74703 | MYBBP1A | 10514 | 1 | 3 | 32 | |
| GSE74704 | MYBBP1A | 10514 | 3 | 1 | 16 | |
| TCGA | MYBBP1A | 10514 | 18 | 21 | 57 |
Total number of gains: 87; Total number of losses: 50; Total Number of normals: 351.
Somatic mutations of MYBBP1A:
Generating mutation plots.
Highly correlated genes for MYBBP1A:
Showing top 20/1017 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| MYBBP1A | BOP1 | 0.774606 | 3 | 0 | 3 |
| MYBBP1A | PIM3 | 0.750359 | 3 | 0 | 3 |
| MYBBP1A | MNT | 0.739237 | 3 | 0 | 3 |
| MYBBP1A | F11R | 0.721842 | 5 | 0 | 5 |
| MYBBP1A | FERMT3 | 0.707897 | 3 | 0 | 3 |
| MYBBP1A | PLA2G15 | 0.703214 | 5 | 0 | 3 |
| MYBBP1A | ZFYVE27 | 0.695228 | 3 | 0 | 3 |
| MYBBP1A | GRHL2 | 0.691023 | 3 | 0 | 3 |
| MYBBP1A | HEATR1 | 0.689886 | 9 | 0 | 8 |
| MYBBP1A | MZB1 | 0.688157 | 3 | 0 | 3 |
| MYBBP1A | FBRSL1 | 0.687023 | 5 | 0 | 4 |
| MYBBP1A | FAM160B2 | 0.684317 | 4 | 0 | 4 |
| MYBBP1A | XXYLT1 | 0.682839 | 3 | 0 | 3 |
| MYBBP1A | ZMYND15 | 0.67555 | 4 | 0 | 3 |
| MYBBP1A | COTL1 | 0.674624 | 3 | 0 | 3 |
| MYBBP1A | NOP58 | 0.666953 | 7 | 0 | 7 |
| MYBBP1A | PODXL2 | 0.664551 | 3 | 0 | 3 |
| MYBBP1A | NIFK | 0.664323 | 6 | 0 | 6 |
| MYBBP1A | DNLZ | 0.661243 | 3 | 0 | 3 |
| MYBBP1A | DHX33 | 0.660028 | 7 | 0 | 5 |
For details and further investigation, click here
