| Full name: MOK protein kinase | Alias Symbol: RAGE1|STK30 | ||
| Type: protein-coding gene | Cytoband: 14q32.31 | ||
| Entrez ID: 5891 | HGNC ID: HGNC:9833 | Ensembl Gene: ENSG00000080823 | OMIM ID: 605762 |
| Drug and gene relationship at DGIdb | |||
Expression of MOK:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | MOK | 5891 | 205130_at | 0.0728 | 0.8982 | |
| GSE20347 | MOK | 5891 | 205130_at | 0.1201 | 0.5368 | |
| GSE23400 | MOK | 5891 | 205130_at | 0.0501 | 0.4867 | |
| GSE26886 | MOK | 5891 | 205130_at | 1.2085 | 0.0034 | |
| GSE29001 | MOK | 5891 | 205130_at | 0.4462 | 0.1941 | |
| GSE38129 | MOK | 5891 | 205130_at | 0.0999 | 0.5630 | |
| GSE45670 | MOK | 5891 | 205130_at | 0.3873 | 0.1080 | |
| GSE53622 | MOK | 5891 | 9167 | 0.5033 | 0.0000 | |
| GSE53624 | MOK | 5891 | 85431 | 0.4763 | 0.0000 | |
| GSE63941 | MOK | 5891 | 205130_at | 1.0707 | 0.2542 | |
| GSE77861 | MOK | 5891 | 205130_at | -0.0848 | 0.5862 | |
| GSE97050 | MOK | 5891 | A_23_P76731 | 0.2329 | 0.4621 | |
| SRP007169 | MOK | 5891 | RNAseq | 2.6311 | 0.0014 | |
| SRP064894 | MOK | 5891 | RNAseq | 0.7741 | 0.0005 | |
| SRP133303 | MOK | 5891 | RNAseq | 0.1253 | 0.3141 | |
| SRP159526 | MOK | 5891 | RNAseq | 0.9813 | 0.0461 | |
| SRP193095 | MOK | 5891 | RNAseq | 0.6040 | 0.0040 | |
| SRP219564 | MOK | 5891 | RNAseq | 0.1691 | 0.7434 |
Upregulated datasets: 2; Downregulated datasets: 0.
Survival by MOK expression:
 |  |
| GSE53622 | GSE53624 |
Note: Click image to view full size file.
Copy number change of MOK:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | MOK | 5891 | 11 | 5 | 14 | |
| GSE20123 | MOK | 5891 | 10 | 4 | 16 | |
| GSE43470 | MOK | 5891 | 7 | 4 | 32 | |
| GSE46452 | MOK | 5891 | 18 | 4 | 37 | |
| GSE47630 | MOK | 5891 | 10 | 9 | 21 | |
| GSE54993 | MOK | 5891 | 3 | 8 | 59 | |
| GSE54994 | MOK | 5891 | 21 | 4 | 28 | |
| GSE60625 | MOK | 5891 | 0 | 2 | 9 | |
| GSE74703 | MOK | 5891 | 6 | 3 | 27 | |
| GSE74704 | MOK | 5891 | 5 | 3 | 12 | |
| TCGA | MOK | 5891 | 32 | 19 | 45 |
Total number of gains: 123; Total number of losses: 65; Total Number of normals: 300.
Somatic mutations of MOK:
Generating mutation plots.
Highly correlated genes for MOK:
Showing top 20/137 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| MOK | AMPD2 | 0.734817 | 3 | 0 | 3 |
| MOK | UROD | 0.718817 | 3 | 0 | 3 |
| MOK | PHF1 | 0.702314 | 3 | 0 | 3 |
| MOK | DOHH | 0.690013 | 3 | 0 | 3 |
| MOK | CDR2L | 0.689414 | 3 | 0 | 3 |
| MOK | ZNF428 | 0.67783 | 3 | 0 | 3 |
| MOK | EDA | 0.676797 | 4 | 0 | 4 |
| MOK | OR7A17 | 0.665618 | 3 | 0 | 3 |
| MOK | ZNF205 | 0.660325 | 4 | 0 | 4 |
| MOK | ZBTB46 | 0.658792 | 3 | 0 | 3 |
| MOK | KRTAP3-1 | 0.655184 | 3 | 0 | 3 |
| MOK | TIMM22 | 0.646814 | 4 | 0 | 3 |
| MOK | RASGEF1A | 0.646313 | 3 | 0 | 3 |
| MOK | NPM2 | 0.644982 | 4 | 0 | 4 |
| MOK | KLHL26 | 0.640416 | 4 | 0 | 3 |
| MOK | LAT | 0.639772 | 3 | 0 | 3 |
| MOK | WNT9A | 0.63757 | 4 | 0 | 3 |
| MOK | IFITM5 | 0.635105 | 3 | 0 | 3 |
| MOK | BLACE | 0.629767 | 3 | 0 | 3 |
| MOK | PRR7 | 0.627509 | 4 | 0 | 3 |
For details and further investigation, click here
