| Full name: DDB1 and CUL4 associated factor 6 | Alias Symbol: PC326 | ||
| Type: protein-coding gene | Cytoband: 1q24.2 | ||
| Entrez ID: 55827 | HGNC ID: HGNC:30002 | Ensembl Gene: ENSG00000143164 | OMIM ID: 610494 |
| Drug and gene relationship at DGIdb | |||
Expression of DCAF6:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | DCAF6 | 55827 | 217908_s_at | 0.2263 | 0.5441 | |
| GSE20347 | DCAF6 | 55827 | 217908_s_at | 0.2768 | 0.0841 | |
| GSE23400 | DCAF6 | 55827 | 217908_s_at | 0.2764 | 0.0002 | |
| GSE26886 | DCAF6 | 55827 | 217908_s_at | 0.0666 | 0.7831 | |
| GSE29001 | DCAF6 | 55827 | 217908_s_at | 0.5497 | 0.1279 | |
| GSE38129 | DCAF6 | 55827 | 217908_s_at | 0.2593 | 0.0537 | |
| GSE45670 | DCAF6 | 55827 | 217908_s_at | 0.1302 | 0.3628 | |
| GSE53622 | DCAF6 | 55827 | 167561 | 0.1149 | 0.1154 | |
| GSE53624 | DCAF6 | 55827 | 13068 | 0.2612 | 0.0000 | |
| GSE63941 | DCAF6 | 55827 | 217908_s_at | -0.8551 | 0.0532 | |
| GSE77861 | DCAF6 | 55827 | 217908_s_at | 0.3714 | 0.1944 | |
| GSE97050 | DCAF6 | 55827 | A_33_P3294449 | -0.4476 | 0.2499 | |
| SRP007169 | DCAF6 | 55827 | RNAseq | 1.0099 | 0.0138 | |
| SRP008496 | DCAF6 | 55827 | RNAseq | 1.1423 | 0.0000 | |
| SRP064894 | DCAF6 | 55827 | RNAseq | 0.2377 | 0.0151 | |
| SRP133303 | DCAF6 | 55827 | RNAseq | 0.4652 | 0.0024 | |
| SRP159526 | DCAF6 | 55827 | RNAseq | 0.2025 | 0.4668 | |
| SRP193095 | DCAF6 | 55827 | RNAseq | 0.2851 | 0.0008 | |
| SRP219564 | DCAF6 | 55827 | RNAseq | -0.1869 | 0.6521 | |
| TCGA | DCAF6 | 55827 | RNAseq | -0.1261 | 0.0046 |
Upregulated datasets: 2; Downregulated datasets: 0.
Survival by DCAF6 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of DCAF6:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | DCAF6 | 55827 | 11 | 1 | 18 | |
| GSE20123 | DCAF6 | 55827 | 11 | 1 | 18 | |
| GSE43470 | DCAF6 | 55827 | 7 | 2 | 34 | |
| GSE46452 | DCAF6 | 55827 | 3 | 1 | 55 | |
| GSE47630 | DCAF6 | 55827 | 14 | 0 | 26 | |
| GSE54993 | DCAF6 | 55827 | 0 | 6 | 64 | |
| GSE54994 | DCAF6 | 55827 | 16 | 0 | 37 | |
| GSE60625 | DCAF6 | 55827 | 0 | 0 | 11 | |
| GSE74703 | DCAF6 | 55827 | 7 | 2 | 27 | |
| GSE74704 | DCAF6 | 55827 | 5 | 0 | 15 | |
| TCGA | DCAF6 | 55827 | 44 | 3 | 49 |
Total number of gains: 118; Total number of losses: 16; Total Number of normals: 354.
Somatic mutations of DCAF6:
Generating mutation plots.
Highly correlated genes for DCAF6:
Showing top 20/465 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| DCAF6 | IRF9 | 0.722384 | 3 | 0 | 3 |
| DCAF6 | NOM1 | 0.688924 | 3 | 0 | 3 |
| DCAF6 | MYLIP | 0.67697 | 3 | 0 | 3 |
| DCAF6 | CARS2 | 0.67285 | 3 | 0 | 3 |
| DCAF6 | ZNF251 | 0.670305 | 4 | 0 | 3 |
| DCAF6 | MYC | 0.665783 | 3 | 0 | 3 |
| DCAF6 | CHIC1 | 0.665311 | 5 | 0 | 4 |
| DCAF6 | BRD9 | 0.664298 | 3 | 0 | 3 |
| DCAF6 | AGPAT4 | 0.659526 | 3 | 0 | 3 |
| DCAF6 | TRIM35 | 0.659043 | 3 | 0 | 3 |
| DCAF6 | AUH | 0.655766 | 3 | 0 | 3 |
| DCAF6 | TERF2IP | 0.653186 | 5 | 0 | 4 |
| DCAF6 | PSMC1 | 0.648557 | 4 | 0 | 3 |
| DCAF6 | ATP6V1H | 0.648064 | 4 | 0 | 3 |
| DCAF6 | PRKAR1A | 0.647747 | 3 | 0 | 3 |
| DCAF6 | CIR1 | 0.64436 | 4 | 0 | 3 |
| DCAF6 | EXOC8 | 0.644148 | 5 | 0 | 4 |
| DCAF6 | NEDD8 | 0.64196 | 4 | 0 | 3 |
| DCAF6 | KLHDC2 | 0.640248 | 4 | 0 | 3 |
| DCAF6 | NUB1 | 0.639375 | 4 | 0 | 3 |
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