DUSP12

 

Full name: dual specificity phosphatase 12 Alias Symbol: YVH1|DUSP1
Type: protein-coding gene Cytoband: 1q23.3
Entrez ID: 11266 HGNC ID: HGNC:3067 Ensembl Gene: ENSG00000081721 OMIM ID: 604835
Drug and gene relationship at DGIdb

 

Expression of DUSP12:

 

Dataset Gene EntrezID Probe Log2FC Adj.pValue Expression
GSE17351 DUSP12 11266 218576_s_at 0.2836 0.3338
GSE20347 DUSP12 11266 218576_s_at 0.8445 0.0000
GSE23400 DUSP12 11266 218576_s_at 0.5093 0.0000
GSE26886 DUSP12 11266 218576_s_at 0.9425 0.0000
GSE29001 DUSP12 11266 218576_s_at 0.6420 0.0117
GSE38129 DUSP12 11266 218576_s_at 0.8117 0.0000
GSE45670 DUSP12 11266 218576_s_at 0.1963 0.2122
GSE53622 DUSP12 11266 16308 0.4025 0.0000
GSE53624 DUSP12 11266 16308 0.6950 0.0000
GSE63941 DUSP12 11266 218576_s_at 0.4436 0.3395
GSE77861 DUSP12 11266 218576_s_at 0.9506 0.0011
GSE97050 DUSP12 11266 A_23_P51508 0.3444 0.1832
SRP007169 DUSP12 11266 RNAseq 1.0142 0.0548
SRP008496 DUSP12 11266 RNAseq 0.9469 0.0109
SRP064894 DUSP12 11266 RNAseq 0.3336 0.0201
SRP133303 DUSP12 11266 RNAseq 0.8004 0.0000
SRP159526 DUSP12 11266 RNAseq 0.6833 0.0012
SRP193095 DUSP12 11266 RNAseq 0.5392 0.0000
SRP219564 DUSP12 11266 RNAseq 0.4418 0.2027
TCGA DUSP12 11266 RNAseq 0.1524 0.0144

Upregulated datasets: 0; Downregulated datasets: 0.  

 

Survival by DUSP12 expression:

 

GSE53622GSE53624TCGA

 

Note: Click image to view full size file.  

Copy number change of DUSP12:

 

Dataset Gene EntrezID Gain Loss Normal Detail
GSE15526 DUSP12 11266 10 0 20
GSE20123 DUSP12 11266 10 0 20
GSE43470 DUSP12 11266 7 2 34
GSE46452 DUSP12 11266 2 1 56
GSE47630 DUSP12 11266 14 0 26
GSE54993 DUSP12 11266 0 5 65
GSE54994 DUSP12 11266 16 0 37
GSE60625 DUSP12 11266 0 0 11
GSE74703 DUSP12 11266 7 2 27
GSE74704 DUSP12 11266 4 0 16
TCGA DUSP12 11266 43 4 49

Total number of gains: 113; Total number of losses: 14; Total Number of normals: 361.  

 

Somatic mutations of DUSP12:

 

Generating mutation plots.

 

Highly correlated genes for DUSP12:

 

Showing top 20/1850 corelated genes with mean PCC>0.5.
Gene1 Gene2 Mean PCC Num. Datasets Num. PCC<0 Num. PCC>0.5
DUSP12CDCA20.751235404
DUSP12ANP32E0.74328411011
DUSP12DESI20.7415521009
DUSP12CKS1B0.7395212012
DUSP12RFC40.73899112011
DUSP12CBX30.72907410010
DUSP12PSMB40.72629212012
DUSP12LINC006740.72591303
DUSP12PFDN20.72121612012
DUSP12SLC25A320.71797311011
DUSP12U2SURP0.712091908
DUSP12DNAJC20.71148310010
DUSP12SLC38A60.709862909
DUSP12CCT30.70680712012
DUSP12MCM60.70489412010
DUSP12SNRPE0.70406212010
DUSP12CENPL0.703578707
DUSP12RHPN20.703072303
DUSP12ZNF2810.70297912011
DUSP12CAD0.7019331009

For details and further investigation, click here