| Full name: heterogeneous nuclear ribonucleoprotein U | Alias Symbol: SAF-A|hnRNPU|FLJ37978|FLJ30202 | ||
| Type: protein-coding gene | Cytoband: 1q44 | ||
| Entrez ID: 3192 | HGNC ID: HGNC:5048 | Ensembl Gene: ENSG00000153187 | OMIM ID: 602869 |
| Drug and gene relationship at DGIdb | |||
Screen Evidence:
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Expression of HNRNPU:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | HNRNPU | 3192 | 200594_x_at | 0.4124 | 0.1285 | |
| GSE20347 | HNRNPU | 3192 | 200594_x_at | 0.5565 | 0.0000 | |
| GSE23400 | HNRNPU | 3192 | 200594_x_at | 0.6255 | 0.0000 | |
| GSE26886 | HNRNPU | 3192 | 200594_x_at | 0.0679 | 0.7351 | |
| GSE29001 | HNRNPU | 3192 | 200594_x_at | 0.4867 | 0.0786 | |
| GSE38129 | HNRNPU | 3192 | 200594_x_at | 0.4858 | 0.0000 | |
| GSE45670 | HNRNPU | 3192 | 200594_x_at | 0.4163 | 0.0005 | |
| GSE53622 | HNRNPU | 3192 | 27981 | 0.1258 | 0.0277 | |
| GSE53624 | HNRNPU | 3192 | 27981 | 0.2851 | 0.0000 | |
| GSE63941 | HNRNPU | 3192 | 200594_x_at | -0.1262 | 0.5794 | |
| GSE77861 | HNRNPU | 3192 | 200594_x_at | 0.7325 | 0.0006 | |
| GSE97050 | HNRNPU | 3192 | A_23_P160862 | 0.1666 | 0.4503 | |
| SRP007169 | HNRNPU | 3192 | RNAseq | 1.5508 | 0.0000 | |
| SRP008496 | HNRNPU | 3192 | RNAseq | 1.4940 | 0.0000 | |
| SRP064894 | HNRNPU | 3192 | RNAseq | 0.2778 | 0.0265 | |
| SRP133303 | HNRNPU | 3192 | RNAseq | 0.4056 | 0.0000 | |
| SRP159526 | HNRNPU | 3192 | RNAseq | 0.4667 | 0.0169 | |
| SRP193095 | HNRNPU | 3192 | RNAseq | 0.2798 | 0.0004 | |
| SRP219564 | HNRNPU | 3192 | RNAseq | 0.4025 | 0.0675 | |
| TCGA | HNRNPU | 3192 | RNAseq | 0.0842 | 0.0224 |
Upregulated datasets: 2; Downregulated datasets: 0.
Survival by HNRNPU expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of HNRNPU:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | HNRNPU | 3192 | 7 | 1 | 22 | |
| GSE20123 | HNRNPU | 3192 | 7 | 1 | 22 | |
| GSE43470 | HNRNPU | 3192 | 6 | 2 | 35 | |
| GSE46452 | HNRNPU | 3192 | 4 | 2 | 53 | |
| GSE47630 | HNRNPU | 3192 | 15 | 0 | 25 | |
| GSE54993 | HNRNPU | 3192 | 0 | 6 | 64 | |
| GSE54994 | HNRNPU | 3192 | 18 | 0 | 35 | |
| GSE60625 | HNRNPU | 3192 | 0 | 0 | 11 | |
| GSE74703 | HNRNPU | 3192 | 6 | 1 | 29 | |
| GSE74704 | HNRNPU | 3192 | 2 | 0 | 18 | |
| TCGA | HNRNPU | 3192 | 46 | 4 | 46 |
Total number of gains: 111; Total number of losses: 17; Total Number of normals: 360.
Somatic mutations of HNRNPU:
Generating mutation plots.
Highly correlated genes for HNRNPU:
Showing top 20/1367 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| HNRNPU | SLC39A13 | 0.798364 | 3 | 0 | 3 |
| HNRNPU | IPO9 | 0.796036 | 7 | 0 | 7 |
| HNRNPU | WDR66 | 0.768783 | 3 | 0 | 3 |
| HNRNPU | SLC39A3 | 0.760662 | 3 | 0 | 3 |
| HNRNPU | ZC3H18 | 0.754341 | 4 | 0 | 4 |
| HNRNPU | SERPINH1 | 0.745774 | 8 | 0 | 7 |
| HNRNPU | PFDN2 | 0.740562 | 9 | 0 | 8 |
| HNRNPU | RFTN1 | 0.739559 | 3 | 0 | 3 |
| HNRNPU | LPCAT1 | 0.734086 | 9 | 0 | 8 |
| HNRNPU | BRAT1 | 0.733816 | 4 | 0 | 4 |
| HNRNPU | FUS | 0.727441 | 10 | 0 | 9 |
| HNRNPU | ELOF1 | 0.725256 | 3 | 0 | 3 |
| HNRNPU | PRICKLE1 | 0.72397 | 4 | 0 | 3 |
| HNRNPU | RPF2 | 0.722531 | 3 | 0 | 3 |
| HNRNPU | HNRNPC | 0.719022 | 10 | 0 | 9 |
| HNRNPU | RTKN | 0.718663 | 4 | 0 | 4 |
| HNRNPU | MTERF3 | 0.717191 | 6 | 0 | 6 |
| HNRNPU | BOLA3 | 0.716167 | 5 | 0 | 5 |
| HNRNPU | IL17RD | 0.71597 | 3 | 0 | 3 |
| HNRNPU | CERS2 | 0.715703 | 8 | 0 | 7 |
For details and further investigation, click here
